# l(3)62 Lethals in thirteen complementation groups isolated in the region uncovered by Df(3L)R-R2 = Df(3L)62B2-4;62D3-5 (Sliter, Henrich, Tucker, and Gilbert, 1989, Genetics 123: 327-36). genetic cytological locus location location included in excluded from synonym __________________________________________________________________ l(3)62Ba 3-{1.5} 62B2-9 Df(3L)R-R2 Df(3L)R-G7 l(3)dre1 l(3)62Bb 3-{1.5} 62B2-9 Df(3L)R-R2 Df(3L)R-G7 l(3)dre9 l(3)62Bc 3-{1.5} 62B2-9 Df(3L)R-R2 Df(3L)R-G7 l(3)dre2 l(3)62Bd 3-{1.5} 62B2-9 Df(3L)R-R2 Df(3L)R-G7 l(3)dre3 l(3)62Be 3-{1.5} 62B2-9 Df(3L)R-R2 Df(3L)R-G7 l(3)neo7 l(3)62Bf 3-1.4 62B8-9 Df(3L)R-G7 Df(3L)R-G2 R l(3)62Bg 3-{1.5} 62B8-12 Df(3L)R-G7 Df(3L)R-G2 l(3)dre4 l(3)62Bh 3-{1.5} 62B8-12 Df(3L)R-G7 Df(3L)R-G2 l(3)dre5 l(3)62Bi 3-{1.5} 62B11-C1 Df(3L)R-G2 Df(3L)R-E l(3)dre6 l(3)62Bj 3-{1.5} 62B11-C1 Df(3L)R-G2 Df(3L)R-E l(3)dre7 l(3)62Ca 3-{1.5} 62B12-D1 Df(3L)R-E Df(3L)R-G5 l(3)dre8 l(3)62Da 3-{1.5} 62B11-C1 Df(3L)R-G5 Df(3L)R-R2 l(3)dre10 l(3)62Db 3-{1.5} 62B11-C1 Df(3L)R-G5 Df(3L)R-R2 ecd allele origin comments ___________________________________ l(3)62Ba1 EMS L3-P l(3)62Ba2 EMS also l(3)Bb1 l(3)62Ba3 / ray L3-P l(3)62Bb1 EMS L2; also l(3)Ba2 l(3)62Bb2 EMS L2 l(3)62Bb3 EMS L2 # l(3)62Bc phenotype: Hemizygous lethal; larvae die in the third instar, with one allele occasionally able to proceed into the prepupal stage. Mature larvae discless; in addition, larval brain, but not the ventral ganglion, greatly reduced in size. allele origin synonym comments ___________________________________________ l(3)62Bc1 EMS l(3)62Bc2 EMS l(3)62Bc3 / ray dre2g17 In(3L)62B2-7;63F # l(3)62Bd phenotype: Hemizygotes die in first larval instar, with one of seven alleles tested occasionally surviving until the second instar. allele origin ___________________ l(3)62Bd1-5 EMS l(3)62Bd6-7 / ray allele origin synonym comments _______________________________________ l(3)62Be1 P l(3)neo71 ( L2; L2/3 l(3)62Be2 EMS l(3)neo7e43 P-A ( Cooley, Kelly, and Spradling, 1988, Science 239: 1121-28. # l(3)62Bg phenotype: Locus displays ca 80 times the mutation rate of most of the other loci in the region, and it is relatively more sensitive to / irradiation than to EMS mutagenesis than other loci (by a factor of six); in addition, none of the alleles is associated with a gross chromosome rearrangement. Hemizygotes are arrested in the first larval instar, where they remain robust and active. One allele temperature sensitive; develop- mental arrest takes place shortly after shift up in tempera- ture at several stages. allele origin ____________________ l(3)62Bg1-18 EMS l(3)62Bg19-74 / ray # l(3) 62Bh phenotype: Hemizygous larvae die during the third instar; one allele displays occasional escapers into the second instar. allele origin comments ________________________________________ l(3)62Bh1 EMS l(3)62Bh2 EMS l(3)62Bh3 EMS l(3)62Bh4 EMS l(3)62Bh5 / ray l(3)62Bi1 EMS temperature sensitive; dies as pharate adult l(3)62Bj1 / ray L1 # l(3)62Ca phenotype: Hemizygotes for seventeen of nineteen alleles die during the first larval instar; four of these show some escape into the second instar; two alleles cause lethality in the pupal-adult stage. allele origin comments _____________________________________________ l(3)62Ca1-12 EMS L1 l(3)62Ca13 / ray L1; T(2;3)27E-F;62C2-D1 l(3)62Ca14 / ray P-A l(3)62Ca15 / ray P-A l(3)62Ca16-19 / ray L1 l(3)62Da1 HD L2 #*l(3)62g origin: Spontaneous. discoverer: Paik. references: 1963, Proc. Intern. Congr. Genet., 11th., Vol. 1: 163-64. other information: A series of 65 lethals recovered from Korean wild populations. # DEFICIENCY MAP OF REGION 62 side breakpoint variant ________________________________ left 62A10-B1 Df(3L)R-G5 left 62B2-4 Df(3L)R-R2 left 62B2-4 Df(3L)R-G2 l(3)62Ba l(3)62Bb l(3)62Bc l(3)62Bd l(3)62Be left 62B8-9 Df(3L)R-E left 62B8-9 Df(3L)R-G7 R Aprt l(3)62Bf l(3)62Bg right 62B11-12 Df(3L)R-G2 l(3)62Bh l(3)62Bi right 62B12-C1 Df(3L)R-E l(3)62Ca right 62C4-D1 Df(3L)R-G5 l(3)62Da ecd right 62D3-5 Df(3L)R-R2 right 62F2-5 Df(3L)R-G7 # l(3)63 Results of saturation mutagenesis of the region of Hsp83 (Wohlwill and Bonner). cytological locus location included in excluded from synonym _______________________________________________________________ l(3)63Aa 63A8-B6 Df(3L)HR218 Df(3L)HR298 l(3)63Ab 63A8-B6 Df(3L)HR218 Df(3L)HR298 l(3)63Ba 63B6-C1 Df(3L)HR218 Df(3L)HR232 l(3)63Bb 63B6-C1 Df(3L)HR218 Df(3L)HR232 l(3)63Bc 63B6-C1 Df(3L)HR218 Df(3L)HR232 l(3)63Bd 63B6-C1 Df(3L)HR218 Df(3L)HR232 l(3)63Be 63B6-C1 Df(3L)HR218 Df(3L)HR232 l(3)63Bf 63B6-C1 Df(3L)HR218 Df(3L)HR232 M(3)63B, M(3)LS3 l(3)63Ea 63D3-F1 Df(3L)HR119 Df(3L)HR232 l(3)63Eb 63D3-F1 Df(3L)HR119 Df(3L)HR232 allele origin discoverer synonym comments _____________________________________________________ l(3)63Aa1 EMS Wohlwill E-33 l(3)63Ab1 EMS Wohlwill E-13 995 l(3)63Ab2 EMS Wohlwill 18-4 l(3)63Ba1 EMS Wohlwill E25-299 l(3)63Bb1 DEB Wohlwill D32-187 l(3)63Bb2 DEB Wohlwill D27-1159 l(3)63Bb3 EMS Wohlwill 9-9 l(3)63Bb4 EMS Wohlwill 9-1 l(3)63Bb5 EMS Wohlwill 1-7 l(3)63Bc1 EMS Wohlwill E-13 564 l(3)63Bc2 EMS Wohlwill 29-12 l(3)63Bc3 EMS Wohlwill 79 l(3)63Bc4 EMS Wohlwill 14-7 l(3)63Bc5 EMS Wohlwill 23-16 leaky l(3)63Bd1 EMS Wohlwill 5-5 l(3)63Bd2 EMS Wohlwill 12-1 l(3)63Be1 EMS Wohlwill 8-1 l(3)63Be2 EMS Wohlwill 1-1 l(3)63Be3 EMS Wohlwill 29-17 l(3)63Be4 EMS Wohlwill 10-5 leaky l(3)63Ea1 EMS Wohlwill 164 l(3)63Eb1 EMS Wohlwill 203 # DEFICIENCY MAP OF REGION 63A-C side breakpoint variant _________________________________ left 62B Dp(3;3)BK14 left 62C1 Dp(3;3)BK7 left 63A1 Df(3L)HR370 left 63A1 Dp(3;3)BK116 left 63B6 Df(3L)HR218 l(3)63Aa l(3)63Ab left 63B6 Df(3L)HR298 l(3)63Ba l(3)63Bb l(3)63Bc l(3)63Bd l(3)63Be M(3)63B left 63C1 Df(3L)HR232 left 63B12-C1 Df(3L)HR277 left 63C6 Df(3L)HR119 left 63C6 Dp(3;3)M2 left 63C6 Dp(3;3)M28 right 63D1 Df(3L)HR218 right 63D1 Df(3L)HR370 right 63D3 Df(3L)HR232 l(3)63Ea l(3)63Eb right 63E9 Df(3L)HR119 right 64A6 Df(3L)HR298 right 64B7 Dp(3;3)M2 right 64B10 Dp(3;3)BK14 right 64B10-12 Dp(3;3)BK116 right 64B10-12 Dp(3;3)BK7 right 64B12 Df(3L)HR277 right 65A Dp(3;3)M28 # l(3)67 Results of saturation mutagenesis experiments in the region uncovered by Df(3L)AC1 = Df(3L)67A2;67D11-13 plus additional saturation of its region of overlap with Df(3L)29A6 = Df(3L)66F3;67B1 (Leicht and Bonner, 1988, Genet- ics 119: 579-93). # l(3)67A Five complementation groups of unknown order; two are included in the cytologically invisible deficiency, Df(3L)e146, whose position in 67A is undetermined. genetic cytological locus location location included in excluded from ________________________________________________________ l(3)67Aa 3-{27} 67A2-B1 Df(3L)29A6 Df(3L)e146 Df(3L)AC1 l(3)67Ab 3-{27} 67A2-B1 Df(3L)29A6 Df(3L)e146 Df(3L)AC1 l(3)67Ac 3-{27} 67A2-B1 Df(3L)e146 l(3)67Ad 3-{27} 67A2-B1 Df(3L)e146 l(3)67Ae 3-{27} 67A2-B1 Df(3L)29A6 Df(3L)e146 Df(3L)AC1 l(3)67Af 3-{27} 67A2-B1 Df(3L)29A6 Df(3L)e146 Df(3L)AC1 allele origin discoverer synonym comments ( _______________________________________________________ l(3)67Aa1 DEB Leicht l(3)d37A1 P-A l(3)67Aa2 DEB Leicht l(3)d174B5 P-A l(3)67Aa3 DEB Leicht l(3)d232A2 P-A l(3)67Aa4 EMS Leicht l(3)e73B3 P-A l(3)67Aa5 EMS Leicht l(3)e106C3 P-A l(3)67Aa6 EMS Matthews l(3)E1.1 P-A l(3)67Ab1 DEB Leicht l(3)d236A1 pharate adults l(3)67Ab2 EMS Leicht l(3)e61c pharate adults l(3)67Ab3 EMS Leicht l(3)e76A1 pharate adults l(3)67Ac1 EMS Leicht l(3)e78B4 young adult | l(3)67Ad1 DEB Leicht l(3)d189B2 L l(3)67Ad2 EMS Leicht l(3)e152C4 L l(3)67Ae1 EMS Leicht l(3)e72A2 L l(3)67Af1 EMS Matthews l(3)e17 E ( Lethal phase of hemizygotes. | Smaller and rougher eyes than wild type; some individuals also have held-back wings. # l(3)67BD Eighteen lethally mutable complementation groups including M(3)67C. Linear order of loci undetermined. genetic cytological locus location location included in excluded from synonym ________________________________________________________________________ l(3)67BDa 3-{28} 67B1-D13 Df(3L)AC1 Df(3L)29A6 l(3)67BDb 3-{28} 67B1-D13 Df(3L)AC1 Df(3L)29A6 l(3)67BDc 3-{28} 67B1-D13 Df(3L)AC1 Df(3L)29A6 l(3)67BDd 3-{28} 67B1-D13 Df(3L)AC1 Df(3L)29A6 l(3)67BDe 3-{28} 67B1-D13 Df(3L)AC1 Df(3L)29A6 l(3)67BDf 3-{28} 67B1-D13 Df(3L)AC1 Df(3L)29A6 l(3)67BDg 3-{28} 67B1-D13 Df(3L)AC1 Df(3L)29A6 l(3)67BDh 3-{28} 67B1-D13 Df(3L)AC1 Df(3L)29A6 l(3)67BDi 3-{28} 67B1-D13 Df(3L)AC1 Df(3L)29A6 l(3)67BDj 3-{28} 67B1-D13 Df(3L)AC1 Df(3L)29A6 l(3)67BDk 3-{28} 67B1-D13 Df(3L)AC1 Df(3L)29A6 l(3)67BDl 3-{28} 67B1-D13 Df(3L)AC1 Df(3L)29A6 l(3)67BDm 3-{28} 67B1-D13 Df(3L)AC1 Df(3L)29A6 l(3)67BDn 3-{28} 67B1-D13 Df(3L)AC1 Df(3L)29A6 l(3)67BDo 3-{28} 67B1-D13 Df(3L)AC1 Df(3L)29A6 M(3)67C, M(3)i l(3)67BDp 3-{28} 67B1-D13 Df(3L)AC1 Df(3L)29A6 l(3)67BDq 3-{28} 67B1-D13 Df(3L)AC1 Df(3L)29A6 l(3)67BDr 3-{28} 67B1-D13 Df(3L)AC1 Df(3L)29A6 allele origin discoverer synonym comments ( ___________________________________________________________ l(3)67BDa1 DEB Leicht l(3)d4d2 l(3)67BDa2 DEB Leicht l(3)d7A5 l(3)67BDa3 DEB Leicht l(3)d17A6 L l(3)67BDa4 DEB Leicht l(3)d36A7 l(3)67BDa5 DEB Leicht l(3)d38A5 l(3)67BDa6 DEB Leicht l(3)d38B5 l(3)67BDa7 DEB Leicht l(3)d54A7 l(3)67BDa8 DEB Leicht l(3)d58A7 weak allele l(3)67BDa9 EMS Leicht l(3)e64A1 P-A l(3)67BDa10 EMS Leicht l(3)e77A5 P-A l(3)67BDa11 EMS Leicht l(3)e81B4 P-A l(3)67BDa12 EMS Leicht l(3)e86D1-1 l(3)67BDa13 EMS Leicht l(3)e105B2 L l(3)67BDa14 EMS Leicht l(3)e122A7 l(3)67BDa15 EMS Leicht l(3)e138A6 l(3)67BDa16 EMS Leicht l(3)e142A2 L l(3)67BDa17 EMS Leicht l(3)e143A1 l(3)67BDa18 EMS Leicht l(3)e153A6 l(3)67BDa19 EMS Leicht l(3)e154B3 P-A l(3)67BDb1 DEB Leicht l(3)d5A1 l(3)67BDb2 DEB Leicht l(3)d7A6 l(3)67BDb3 DEB Leicht l(3)d10A3 E l(3)67BDb4 DEB Leicht l(3)d49A5 E l(3)67BDb5 EMS Leicht l(3)e66A5 l(3)67BDb6 EMS Leicht l(3)e75B4 P-A l(3)67BDb7 EMS Leicht l(3)e86D1-2 E l(3)67BDb8 EMS Leicht l(3)e113A1-2 L-P l(3)67BDb9 EMS Leicht l(3)e132A7 pharate adults l(3)67BDc1 DEB Leicht l(3)d8A1 l(3)67BDc2 DEB Leicht l(3)d14A3 L l(3)67BDc3 DEB Leicht l(3)d49A3 l(3)67BDc4 EMS Leicht l(3)e90C3 L-P l(3)67BDc5 EMS Leicht l(3)e97B3 L l(3)67BDd1 DEB Leicht l(3)d44A2 l(3)67BDd2 DEB Leicht l(3)d48A6 L l(3)67BDd3 EMS Leicht l(3)e78A1 L l(3)67BDd4 EMS Leicht l(3)e113A1-1 L l(3)67BDd5 EMS Leicht l(3)e154A1 L l(3)67BDe1 DEB Leicht l(3)d10A5 L l(3)67BDe2 DEB Leicht l(3)d14A5 l(3)67BDe3 DEB Leicht l(3)d49A4 l(3)67BDe4 EMS Leicht l(3)E150C4 L l(3)67BDf1 DEB Leicht l(3)d23A3 l(3)67BDf2 DEB Leicht l(3)d35A6 E l(3)67BDf3 EMS Leicht l(3)e2J187 L l(3)67BDg1 DEB Leicht l(3)d7A3 l(3)67BDg2 DEB Leicht l(3)d19A3 L-P l(3)67BDg3 EMS Leicht l(3)e88B2 P-A l(3)67BDg4 EMS Leicht l(3)e94A5 L-P l(3)67BDh1 DEB Leicht l(3)d14A7 l(3)67BDh2 DEB Leicht l(3)d45C2 L l(3)67BDh3 EMS Leicht l(3)e94D1 homozygotes die as adults l(3)67BDh4 EMS Leicht l(3)e140B1 homozygotes die as adults l(3)67BDi1 DEB Leicht l(3)d4A3 l(3)67BDi2 DEB Leicht l(3)d51B2 L-P l(3)67BDj1 DEB Leicht l(3)e73B2 P-A l(3)67BDk1 DEB Leicht l(3)d11A5 l(3)67BDl1 DEB Leicht l(3)d33A3 l(3)67BDl2 EMS Leicht l(3)e154A2 L l(3)67BDm1 DEB Leicht l(3)d47B5 L-P l(3)67BDn1 DEB Leicht l(3)d50A1 P-A l(3)67BDp1 EMS Leicht l(3)e105A3 l(3)67BDq1 EMS Leicht l(3)e83A1 P-A l(3)67BDr1 EMS Leicht l(3)e97C2 P-A ( Lethal phase of hemizygotes. # DEFICIENCY MAP OF REGION 67 side breakpoint variant ________________________________ left 66F3 Df(3L)29A6 left 67A2 Df(3L)AC1 l(3)67Aa l(3)67Ab l(3)67Ac l(3)67Ad l(3)67Ae l(3)67Af right 67B1 Df(3L)29A6 l(3)67BDa l(3)67BDb l(3)67BDc l(3)67BDd l(3)67BDe l(3)67BDf l(3)67BDg l(3)67BDh l(3)67BDi l(3)67BDj l(3)67BDk l(3)67BDl l(3)67BDm l(3)67BDn M(3)67C l(3)67BDp l(3)67BDq l(3)67BDr right 67D11-13 Df(3L)AC1 left 67F Df(3L)P20 left 67E1-2 Df(3L)Ez6 67E1-4 E(z) left 67E3-4 Df(3L)Ez3 right 67E3-5 Df(3L)Ez6 right 67E6-7 Df(3L)Ez3 left 67F2-3 Df(3L)vin2 # l(3)68 A collection of chemically-induced lethals in the region flanking the 68C glu gene cluster on chromosome three (Crosby and Meyerowitz, l986, Genetics 112: 785-802). They have been mapped with deficiencies as well as recombinationally. The order of loci reflects the map order of the mutants except for l(3)68Am, which has not been recombinationally mapped. Hoogwerf, Akam, and Roberts (unpublished) have extended the analysis through 68F. An independent sample of chemically- induced lethal mutations uncovered by Df(3L)lxd9 was selected and complementation mapped by Campbell, Hilliker, and Phillips (1986, Genetics, 112: 205-15). The latter sample of mutants has not been tested against those of Crosby and Meyerowitz, and the breakpoints of Df(3L)lxd9 and the lxd locus are the only points shared by the analysis with the other two. Since gene order was determined using recombination by Crosby and Meyerowitz, their map is used as standard; the findings of Campbell, Hilliker, and Phillips are noted in the deficiency map of the region. genetic cytological locus location location included in excluded from synonym __________________________________________________________________________ l(3)68Aa 3-{35} 68A3-4 Df(3L)vin5 Df(3L)lxd9 l(3)C288 l(3)68Ab 3-{35} 68A3-4 Df(3L)vin5 Df(3L)lxd9 l(3)C493 l(3)68Ac 3-{35} 68A4-6 Df(3L)lxd8 l(3)C117 Df(3L)lxd9 l(3)68Ad 3-35.7 68A5-9 Df(3L)lxd9 Df(3L)lxd8 l(3)517 l(3)68Ae 3-{35} 68A5-9 Df(3L)lxd9 Df(3L)lxd8 l(3)C178 l(3)68Af 3-{35} 68A5-9 Df(3L)lxd9 Df(3L)lxd8 l(3)C206 l(3)68Ag 3-{35} 68A5-9 Df(3L)lxd9 Df(3L)lxd8 l(3)C404 l(3)68Ah 3-{35} 68A5-9 Df(3L)lxd9 Df(3L)lxd8 l(3)C11 l(3)68Ai 3-{35} 68A5-9 Df(3L)lxd9 Df(3L)lxd8 l(3)C46 l(3)68Aj 3-{35} 68A5-9 Df(3L)lxd9 Df(3L)lxd8 l(3)C141 l(3)68Ak 3-{35} 68A5-9 Df(3L)lxd9 Df(3L)lxd8 l(3)C557 l(3)68Al 3-{35} 68A5-9 Df(3L)lxd9 Df(3L)lxd8 l(3)C28 l(3)68Am 3-{35} 68A5-9 Df(3L)lxd9 Df(3L)lxd8 l(3)B76 allele origin discoverer synonym ref ( comments ________________________________________________________________________ l(3)68Aa1 EMS Crosby l(3)C288a 1 L3 l(3)68Aa2 EMS Crosby l(3)C288b 1 l(3)68Aa3 EMS Crosby l(3)C288c 1 l(3)68Aa4 EMS Crosby l(3)C288d 1 l(3)68Aa5 ENU Villenueve l(3)C288e 1 semilethal; adults with thin bristles l(3)68Aa6 ENU Villenueve l(3)C288f 1 l(3)68Aa7 ENU Villenueve l(3)C288g 1 l(3)68Aa8 DEB Crosby l(3)C288h 1 l(3)68Aa9 DEB Crosby l(3)C288i 1 l(3)68Ab1 DEB Crosby l(3)C493a 1 L1 l(3)68Ab2 EMS Crosby l(3)C493b 1 l(3)68Ab3 EMS Crosby l(3)C493c 1 l(3)68Ab4 EMS Crosby l(3)C493d 1 semilethal; adults with rough eyes l(3)68Ac1 EMS Crosby l(3)C117a 1 L2 l(3)68Ac2 ENU Crosby l(3)C117b 1 l(3)68Ac3 ENU Villenueve l(3)C117c 1 l(3)68Ac4 EMS Crosby l(3)C117d 1 ( 1 = Crosby and Meyerowitz, 1986, Genetics 112: 785-802. # l(3)68Ad phenotype: Homozygote lethal at prepupal stage; imaginal discs small. Mitotic figures normal (Gatti). allele origin discoverer synonym ref ( comments _______________________________________________________________________________ l(3)68Ad1 NNG Shearn l(1)517 2 L3-EP l(3)68Ad2 EMS Crosby l(3)517b 1 L3 l(3)68Ad3 EMS Crosby l(3)517c 1 l(3)68Ad4 EMS Crosby l(3)517d 1 semilethal; adults with dusky wings l(3)68Ae1 EMS Crosby l(3)C178a 1 EP l(3)68Ae2 ENU Villenueve l(3)C178b 1 l(3)68Ae3 ENU Villenueve l(3)C178c 1 semilethal; adults with small wings, malformed legs; variable penetrance l(3)68Ae4 DEB Crosby l(3)C178d 1 l(3)68Ae5 DEB Martin l(3)C178e 1 l(3)68Af1 ENU Crosby l(3)C206a 1 EP l(3)68Af2 ENU Villenueve l(3)C206b 1 l(3)68Ag1 ENU Villenueve l(3)C404a 1 L2 l(3)68Ag2 ENU Villenueve l(3)C404b 1 l(3)68Ag3 ENU Villenueve l(3)C404c 1 l(3)68Ag4 ENU Villenueve l(3)C404d 1 l(3)68Ag5 EMS Crosby l(3)C404e 1 semilethal; adults with small, thin bristles l(3)68Ah1 EMS Crosby l(3)C11a 1 E l(3)68Ah2 ENU Crosby l(3)C11b 1 l(3)68Ai1 EMS Crosby l(3)C46a 1 L1-L2 l(3)68Ai2 EMS Crosby l(3)C46b 1 l(3)68Ai3 EMS Crosby l(3)C46c 1 l(3)68Ai4 EMS Crosby l(3)C46d 1 semilethal; adults with upright or outspread wings; variable penetrance; female sterile l(3)68Ai5 ENU Villenueve l(3)C46e 1 l(3)68Ai6 ENU Villenueve l(3)C46f 1 l(3)68Ai7 ENU Villenueve l(3)C46g 1 l(3)68Ai8 ENU Villenueve l(3)C46h 1 same as l(3)68Ai4 l(3)68Ai9 DEB Crosby l(3)C46i 1 l(3)68Aj1 EMS Crosby l(3)C141a 1 EP l(3)68Aj2 EMS Crosby l(3)C141b 1 l(3)68Aj3 DEB Crosby l(3)C141c 1 l(3)68Ak1 ENU Villenueve l(3)C57a 1 EP ( 1 = Crosby and Meyerowitz, 1986, Genetics 112: 785-802. 2 = Shearn, Rice, Garen, and Gehring, 1971, Proc. Nat. Acad. Sci. USA 68: 2594-98. # l(3)68Al Alleles at this locus exhibit complex complementation rela- tions. allele origin discoverer synonym ref ( comments ____________________________________________________________________________ l(3)68Al1 EMS Crosby l(3)C28a1 1 l(3)68Al2 EMS Crosby l(3)C28a2 1 l(3)68Al3 EMS Crosby l(3)C28b1 1 E-L l(3)68Al4 EMS Crosby l(3)C28b2 1 temperature sensitive l(3)68Al5 EMS Crosby l(3)C28c1 1 E-L l(3)68Al6 EMS Crosby l(3)C28c2 1 l(3)68Al7 ENU Villenueve l(3)C28c3 1 l(3)68Al8 ENU Crosby l(3)C28c4 1 l(3)68Al9 EMS Crosby l(3)C28d1 1 l(3)68Al10 ENU Villenueve l(3)C28e1 1 ( 1 = Crosby and Meyerowitz, 1986, Genetics 112: 785-802. # l(3)68Am phenotype: Semilethal; polyphasic. Adults with malformed legs, less often stunted wings; variable penetrance. allele origin discoverer synonym ref ( comments _____________________________________________________________ l(3)68Am1 EMS Roberts l(3)B76 1, 3 L-P l(3)68Am2 EMS Crosby l(3)B76b 2 LP-A ( 1 = Akam, Roberts, Richards, and Ashburner, l978, Cell 13: 215-25; 2 = Crosby and Meyerowitz, 1986, Genetics 112: 785-802. 3 = Roberts and Evans-Roberts, 1976, Mol. Gen. Genet. 148: 57-64. genetic cytological locus location location included in excluded from synonym __________________________________________________________________________ l(3)68Ca 3-{36} 68C8-11 Df(3L)vin3 Df(3L)vin7 l(3)v4-2 l(3)68Cb 3-{36} 68C8-11 Df(3L)vin7 Df(3L)vin6 l(3)C605 l(3)68Cc 3-{36} 68C8-11 Df(3L)vin7 Df(3L)vin6 l(3)C70 l(3)68Cd 3-{36} 68C8-D3 Df(3L)vin6 l(3)rsg3 Df(3L)vin66 l(3)68Ce 3-{36} 68C8-D3 Df(3L)vin6 l(3)rsg4 Df(3L)vin66 l(3)68Cf 3-{36} 68C8-D3 Df(3L)vin6 l(3)rsg5 Df(3L)vin66 l(3)68Cg 3-{36} 68C8-D3 Df(3L)vin6 l(3)rsg6 Df(3L)vin66 l(3)68Ch 3-{36} 68C8-D3 Df(3L)vin6 l(3)rsg7 Df(3L)vin66 allele origin discoverer synonym ref ( comments ________________________________________________________________________ l(3)68Ca1 EMS Akam l(3)v4-2 1 P-A; semilethal temperature sensitive l(3)68Cb1 EMS Crosby l(3)C605 2 L3 l(3)68Cb2 DEB Martin l(3)C605 2 l(3)68Cc1 EMS Crosby l(3)C70 2 P-A; semilethal; adults with dusky wings, thin bristles l(3)68Cd1 EMS l(3)V4-3 1, 3 l(3)68Cd2 EMS l(3)BID 3 l(3)68Ce1 EMS l(3)V7-1 1, 3 l(3)68Cf1 EMS l(3)154 3 l(3)68Cg1 EMS l(3)27-2 3 l(3)68Cg2 EMS l(3)90 3 l(3)68Cg3 EMS Meyerowitz l(3)113.178 3 l(3)68Cg4 EMS Meyerowitz l(3)113.253 3 l(3)68Ch1 EMS Meyerowitz l(3)112.10 3 l(3)68Ch2 EMS Meyerowitz l(3)112.204 3 l(3)68Ch3 EMS Meyerowitz l(3)113.441 3 ( 1 = Akam, Roberts, Richards, and Ashburner, l978, Cell 13: 215-25; 2 = Crosby and Meyerowitz, 1986, Genetics 112: 785-802; 3 = Hoogwerf, Akam, and Roberts, 1988, Genetics 118: 665-70. genetic cytological locus location location included in excluded from synonym ___________________________________________________________________________ l(3)68Da 3-{36} 68D3-6 Df(3L)vin2 Df(3L)vin66 l(3)rsg8 l(3)68Db 3-{36} 68D3-6 Df(3L)vin2 Df(3L)vin66 l(3)rsg9 l(3)68Dc 3-{36} 68D3-6 Df(3L)vin2 Df(3L)vin66 l(3)rsg10 allele origin synonym ref ( ______________________________________ l(3)68Da1 EMS l(3)1.4 1 l(3)68Db1 EMS l(3)12.5B 1 l(3)68Dc1 EMS l(3)146 1 l(3)68Dc2 EMS l(3)155 1 ( 1 = Hoogwerf, Akam, and Roberts, 1988, Genetics 118: 665- 70. genetic cytological locus location location included in excluded from synonym _________________________________________________________________________________ l(3)68Ea 3-{36} 68D6-E4 Df(3L)vin3 Df(3L)vin2 CycA, l(3)rsg11 l(3)68Eb 3-{36} 68D6-E4 Df(3L)vin3 Df(3L)vin2 l(3)rsg12 l(3)68Ec 3-{36} 68D6-E4 Df(3L)vin3 Df(3L)vin2 l(3)rsg13 l(3)68Ed 3-{36} 68D6-E4 Df(3L)vin3 Df(3L)vin2 l(3)rsg14 l(3)68Ee 3-{36} 68D6-E4 Df(3L)vin3 Df(3L)vin2 l(3)rsg15 l(3)68Ef 3-{37} 68E3-4 Df(3L)P20 Df(3L)vin3 l(3)rsg16 l(3)68Eg 3-{37} 68E3-4 Df(3L)P20 Df(3L)vin3 l(3)rsg17 allele origin discoverer synonym ref ( comments ______________________________________________________________________ l(3)68Eb1 EMS l(3)107 2 l(3)68Ec1 EMS Meyerowitz l(3)106.19 2 l(3)68Ed1 EMS l(3)5 2 l(3)68Ee1 EMS l(3)137 2 l(3)68Ee2 EMS l(3)141A 2 l(3)68Ef1 EMS l(3)16-2 2 l(3)68Eg1 X ray l(3)P20 2 associated with Tp(3;3)UbxP20 ( 1 = Akam, Roberts, Richards, and Ashburner, 1978, Cell 13: 215-25; 2 = Hoogwerf, Akam, and Roberts, 1988, Genetics 118: 665-70. genetic cytological locus location location included in excluded from synonym ___________________________________________________________________________ l(3)68Fa 3-{37} 68E3-6 Df(3L)vin4 Df(3L)P20 l(3)rsg18 l(3)68Fb 3-{37} 68E3-6 Df(3L)vin4 Df(3L)P20 l(3)rsg19 l(3)68Fc 3-{37} 68E3-6 Df(3L)vin4 Df(3L)P20 l(3)rsg20 l(3)68Fd 3-{37} 68E3-6 Df(3L)vin4 Df(3L)P20 l(3)rsg21 l(3)68Fe 3-{37} 68E3-6 Df(3L)vin8 Df(3L)vin4 l(3)rsg22 l(3)68Ff 3-{37} 68E3-6 Df(3L)vin8 Df(3L)vin4 l(3)rsg23 allele origin discoverer synonym ref ( _____________________________________________________ l(3)68Fa1 EMS l(3)FII 2 l(3)68Fa2 EMS l(3)V4-1 1, 2 l(3)68Fa3 EMS l(3)V4-5ts 1, 2 l(3)68Fa4 ICR170 Shearn l(3)VII-5 2, 3 l(3)68Fb1 EMS l(3)49 2 l(3)68Fc1 EMS l(3)BIP 2 l(3)68Fc2 spont l(3)igh 2 l(3)68Fd1 EMS l(3)1B 2 l(3)68Fe1 EMS l(3)69 2 l(3)68Fe2 EMS Meyerowitz l(3)112.226 2 l(3)68Fe3 EMS l(3)113 2 l(3)68Ff1 EMS l(3)21-2 2 l(3)68Ff2 EMS Meyerowitz l(3)112.139 2 l(3)68Ff3 EMS Meyerowitz l(3)112.143 2 l(3)68Ff4 EMS Meyerowitz l(3)112.186 2 l(3)68Ff5 EMS Meyerowitz l(3)112.25 2 l(3)68Ff6 EMS l(3)DII 2 ( 1 = Akam, Roberts, Richards, and Ashburner, 1978, Cell 13: 215-25; 2 = Hoogwerf, Akam, and Roberts, 1988, Genetics 118: 665-70; 3 = Shearn, 1974, Genetics 77: 115-25. # DEFICIENCY MAP OF REGION 68 side breakpoint variant ( variant | ________________________________________________________ left 67E Df(3L)lxd15 left Df(3L)lxd6 left 67F Df(3L)P20 left 67F2-3 Df(3L)vin2 rs left 68A2-3 Df(3L)lxd2 left 68A2-3 Df(3L)lxd8 left 68A2-3 Df(3L)vin5 left 68A2-3 Df(3L)vin66 l(3)68Aa l(3)68Ab left 68A3-4 Df(3L)h1 left 68A3-4 Df(3L)lxd9 Df(3L)lxd9 l(3)68Ac H = l(3)68Ac (1) left 68A3-4 Df(3L)h5 left 68A3-4 Df(3L)h8 left invisible Df(3L)h9 lxd lxd left Df(3L)h2 left Df(3L)h76 l(3)68Ad D = l(3)68Ad (4) right 68A5-6 Df(3L)lxd8 left invisible Df(3L)h9 J = l(3)68Ae (1) cSod = l(3)68Af (1) E = l(3)68Ag (4) l(3)68Ad l(3)68Ae l(3)68Af l(3)68Ag l(3)68Ah l(3)68Ai l(3)68Aj l(3)68Ak l(3)68Al l(3)68Am left 68A8-B1 Df(3L)l-3 right Df(3L)h76 A = l(3)68Ba (2) B = l(3)68Bb (4) I = l(3)68Bc (2) F = l(3)68Bd (4) right Df(3L)h2 C = l(3)68Be (4) left 68A8-9 or Df(3L)vin4 68B1-3? right 68B4-C1 Df(3L)h1 right 68B4-C1 Df(3L)lxd9 Df(3L)lxd9 right 68B4-C1 Df(3L)h5 right 68B4-C1 Df(3L)h8 right 68B4-C1 Df(3L)l-3 right 68C1-2 Df(3L)lxd6 right Df(3L)lxd2 left 68C2-3 Df(3L)vin8 Sgs3 left Df(3L)BK9 left Df(3L)Est6-1 left 68C5-6 Df(3L)vin9 left 68C8-11 Df(3L)vin3 l(3)68Ca left 68C8-11 Df(3L)vin7 l(3)68Cb rt l(3)68Cc left 68C8-11 Df(3L)vin6 right 68C10-15 Df(3L)lxd15 l(3)68Cd l(3)68Ce l(3)68Cf l(3)68Cg l(3)68Ch vin right 68D3 Df(3L)vin66 l(3)68Da l(3)68Db l(3)68Dc right 68D6 Df(3L)vin2 l(3)68Ea l(3)68Eb l(3)68Ec l(3)68Ed l(3)68Ee right 68E3-4 Df(3L)vin3 l(3)68Ef l(3)68Eg right 68E3-4 Df(3L)P20 l(3)68Fa l(3)68Fb l(3)68Fc l(3)68Fd Lsp2 right 68F3-6 Df(3L)vin4 l(3)68Fe left invisible Df(3L)vin10 l(3)68Ff right Df(3L)BK9 right Df(3L)Est6-1 right 68F3-6 Df(3L)vin8 ( Crosby and Meyerowitz, l986, Genetics 112: 785-802; Hoogwerf, Akam, and Roberts, 1988, Genetics 118: 665-70. | Campbell, Hilliker, and Phillips, l986, Genetics 112: 205- 15; the letters preceeding mutant designations are the ori- ginal symbols used by the authors, and the numbers in parentheses following represent the numbers of alleles recovered. Variants common to the two studies occupy the same lines. # l(3)69A-B The extension of the saturation mutagenesis investigation of the region around Lsp of Hoogwerf, Akam, and Roberts (1988, Genetics 118: 665-70). genetic cytological locus location location included in excluded from synonym _____________________________________________________________________________ l(3)69Aa 3-{37} 68F3-69A3 Df(3L)vin5 Df(3L)vin8 l(3)rsg24 l(3)69Ab 3-{37} 68F3-69A3 Df(3L)vin5 Df(3L)vin8 l(3)rsg25 l(3)69Ac 3-{38} 69A1-5 Df(3L)vin6 Df(3L)vin5 l(3)rsg26 l(3)69Ad 3-{38} 69A1-5 Df(3L)vin6 Df(3L)vin5 l(3)rsg27 l(3)69Ae 3-{38} 69A4-B1 Df(3L)vin9 Df(3L)vin6 l(3)rsg28 l(3)69Af 3-{38} 69A4-B1 Df(3L)vin9 Df(3L)vin6 l(3)rsg29 l(3)69Ag ( 3-{38} 69A4-B1 Df(3L)vin9 Df(3L)vin6 l(3)rsg30 ( No mutant allele recovered; lethally-mutable locus inferred from the inability of Df(3L)vin10 to complement Df(3L)vin9, although complementing both l(3)69Ae and l(3)69Af alleles. allele origin synonym ref ( _____________________________________ l(3)69Aa1 EMS l(3)145 1 l(3)69Ab1 EMS l(3)58-2 1 l(3)69Ac1 EMS l(3)163 1 l(3)69Ad1 EMS l(3)62-2 1 l(3)69Ae1 EMS l(3)N24 1 l(3)69Af1 EMS l(3)21b 1 ( 1 = Hoogwerf, Akam, and Roberts, 1988, Genetics 118: 665- 70. genetic cytological locus location location included in excluded from synonym ___________________________________________________________________________ l(3)69Ba 3-{38} 69A5-B5 Df(3L)vin7 Df(3L)vin9 l(3)rsg31 l(3)69Bb 3-{38} 69A5-B5 Df(3L)vin7 Df(3L)vin9 l(3)rsg32 l(3)69Bc 3-{38} 69A5-B5 Df(3L)vin7 Df(3L)vin9 l(3)rsg33 l(3)69Bd 3-{38} 69A5-B5 Df(3L)vin7 Df(3L)vin9 l(3)rsg34 allele origin synonym ref ( _____________________________________ l(3)69Ba1 EMS l(3)74 1 l(3)69Ba2 EMS l(3)141 1 l(3)69Bb1 EMS l(3)12-5 1 l(3)69Bc1 EMS l(3)47 1 l(3)69Bd1 EMS l(3)13 1 ( 1 = Hoogwerf, Akam, and Roberts, 1988, Genetics 118: 665- 70. # DEFICIENCY MAP OF REGION 69A-B side breakpoint variant ________________________________ right 68F3-6 Df(3L)vin8 l(3)69Aa right invisible Df(3L)vin10 l(3)69Ab right 69A1-3 Df(3L)vin5 app Est6 l(3)69Ac l(3)69Ad right 69A4-5 Df(3L)vin6 l(3)69Ae l(3)69Af left invisible Df(3L)vin11 l(3)69Ag right 69A5-B1 Df(3L)vin9 l(3)69Ba right invisible Df(3L)vin11 l(3)69Bb l(3)69Bc l(3)69Bd right 69B4-5 Df(3L)vin7 gv eyg # l(3)70Aa Four interallelic complementation groups as follows: (alleles 5 and 7) (allele1) (allele3) (allele4); alleles 2 and 6 are noncomplementing except that l(3)70Aa6 complements l(3)70Aa4 at 30. genetic cytological locus location location included in synonym _________________________________________________________ l(3)70Aa 3-40.5 70A2-6 Df(3L)Ly l(3)ZF1 l(3)70Ab 3-40.5 70A2-6 Df(3L)Ly l(3)ZF2 l(3)70Ac 3-40.5 70A2-6 Df(3L)Ly l(3)ZF3 allele origin synonym ref ( _______________________________________ l(3)70Aa1 EMS l(3)ZF1A1 1 l(3)70Aa2 EMS l(3)ZF1G1 1 l(3)70Aa3 EMS l(3)ZF1G2 1 l(3)70Aa4 EMS l(3)ZF1F15 1 l(3)70Aa5 EMS l(3)ZF1F83 1 l(3)70Aa6 EMS l(3)ZF1F85 1 l(3)70Aa7 EMS l(3)ZF1F86 1 l(3)70Ab1 EMS l(3)ZF2F16 1 l(3)70Ab2 EMS l(3)ZF2F22 1 l(3)70Ac1 EMS l(3)ZF3A2 1 ( 1 = Zhimulev and Feldman, l982, DIS 58: 152. # l(3)72A-D (J.A. Kennison) Twenty one lethally mutable loci, including arl, brm and th defined by complementation analysis of 95 ethyl-methanesulfo- nate-induced recessive lethal mutations uncovered by Df(3L)th102 (Kennison and Brizuela). genetic cytological locus location location included in excluded from synonym _________________________________________________________________ l(3)72Aa 3-43.0 71F-72B1 Df(3L)th1-2 Df(3L)th117 brm l(3)72Ab 3-{43} 71F-72B1 Df(3L)th1-2 Df(3L)th117 l(3)72Ac 3-{43} 71F-72B1 Df(3L)th1-2 Df(3L)th117 l(3)72Ad 3-{43} 71F-72B1 Df(3L)th1-2 Df(3L)th117 l(3)72Ae 3-{43} 71F-72B1 Df(3L)th1-2 Df(3L)th117 arl allele origin discoverer comments ___________________________________________ l(3)72Ab1 EMS Kennison l(3)72Ab2 EMS Kennison l(3)72Ab3 EMS Kennison l(3)72Ab4 EMS Kennison l(3)72Ab5 EMS Kennison l(3)72Ab6 EMS Kennison l(3)72Ac1 EMS Kennison l(3)72Ac2 EMS Kennison l(3)72Ac3 EMS Kennison l(3)72Ac4 EMS Kennison l(3)72Ac5 EMS Kennison l(3)72Ac6 EMS Kennison l(3)72Ac7 EMS Kennison l(3)72Ac8 EMS Kennison l(3)72Ad1 EMS Kennison l(3)72Ad2 EMS Brizuela mutant for brm genetic cytological locus location location included in excluded from synonym __________________________________________________________________ l(3)72Da 3-{43} 72D1-5 Df(3L)st-g24 Df(3L)st-e4 Df(3L)brm11 l(3)72Db 3-{43} 72D1-5 Df(3L)st-g24 Df(3L)st-e4 Df(3L)brm11 l(3)72Dc 3-43.2 72D1-5 Df(3L)st-g24 Df(3L)st-e4 th Df(3L)brm11 l(3)72Dd 3-{43} 72D5 Df(3L)st-e4 Df(3L)brm11 Df(3L)th117 l(3)72De 3-{43} 72D5-11 Df(3L)st-e4 Df(3L)st4 l(3)72Df 3-{43} 72D5-11 Df(3L)st-e4 Df(3L)st4 l(3)72Dg 3-{43} 72D5-11 Df(3L)st-e4 Df(3L)st4 l(3)72Dh 3-{43} 72D5-11 Df(3L)st-e4 Df(3L)st4 l(3)72Di 3-{43} 72D5-11 Df(3L)st-e4 Df(3L)st4 l(3)72Dj 3-{43} 72D5-11 Df(3L)st-e4 Df(3L)st4 l(3)72Dk 3-{43} 72D5-11 Df(3L)st-e4 Df(3L)st4 l(3)72Dl 3-{43} 72D5-11 Df(3L)st-e4 Df(3L)st4 l(3)72Dm 3-{43} 72D5-11 Df(3L)st-e4 Df(3L)st4 l(3)72Dn 3-{43} 72D7-11 Df(3L)st4 Df(3L)st-b11 l(3)72Do 3-{43} 72D7-11 Df(3L)st4 Df(3L)st-b11 l(3)72Dp 3-{43} 72D10-12 Df(3L)st-b11 Df(3L)th102 allele origin discoverer comments __________________________________________________ l(3)72Da1 EMS Kennison l(3)72Da2 EMS Kennison l(3)72Da3 EMS Kennison l(3)72Da4 EMS Brizuela semi-lethal l(3)72Db1 EMS Kennison l(3)72Db2 EMS Kennison l(3)72Db3 EMS Kennison l(3)72Db4 EMS Kennison l(3)72Db5 EMS Kennison l(3)72Db6 EMS Kennison l(3)72Db7 EMS Kennison l(3)72Db8 EMS Kennison l(3)72Db9 EMS Brizuela l(3)72Db10 EMS Brizuela l(3)72Db11 EMS Brizuela l(3)72Db12 EMS Brizuela l(3)72Db13 EMS Brizuela l(3)72Db14 EMS Brizuela l(3)72Db15 EMS Brizuela l(3)72Db16 EMS Brizuela l(3)72Db17 EMS Brizuela l(3)72Db18 EMS Brizuela l(3)72Db19 EMS Brizuela l(3)72Db20 EMS Brizuela l(3)72Db21 EMS Brizuela l(3)72Db22 EMS Brizuela l(3)72Db23 __2-3 Kennison haplo-speific lethal l(3)72Dd1 EMS Kennison l(3)72Dd2 EMS Kennison l(3)72Dd3 EMS Brizuela l(3)72Dd4 EMS Brizuela l(3)72Dd5 EMS Brizuela l(3)72Dd6 EMS Brizuela l(3)72De1 EMS Kennison l(3)72De2 EMS Kennison l(3)72De3 EMS Kennison l(3)72De4 EMS Kennison l(3)72De5 EMS Kennison l(3)72De6 EMS Brizuela l(3)72Df1 EMS Kennison l(3)72Df2 EMS Kennison l(3)72Df3 EMS Kennison l(3)72Df4 EMS Kennison l(3)72Df5 EMS Kennison l(3)72Df6 EMS Brizuela l(3)72Dg1 EMS Kennison l(3)72Dg2 EMS Kennison l(3)72Dg3 EMS Kennison l(3)72Dg4 EMS Kennison l(3)72Dh1 EMS Kennison l(3)72Di1 EMS Kennison l(3)72Dj1 EMS Kennison l(3)72Dk1 EMS Brizuela l(3)72Dl1 EMS Kennison l(3)72Dl2 EMS Brizuela l(3)72Dm1 EMS Kennison l(3)72Dm2 EMS Kennison l(3)72Dn1 EMS Kennison l(3)72Dn2 EMS Brizuela l(3)72Do1 EMS Kennison l(3)72Dp1 EMS Kennison l(3)72Dp2 EMS Kennison l(3)72Dp3 EMS Kennison l(3)72Dp4 EMS Kennison # DEFICIENCY MAP OF REGION 72A-72D side breakpoint variant _________________________________ left 71F Df(3L)brm11 left 71F-72A1 Df(3L)th102 brm l(3)72Aa l(3)72Ab l(3)72Ac l(3)72Ad arl left 72B1 Df(3L)th117 left 72C1-D1 Df(3L)st-f13 left 72D1-2 Df(3L)st-g24 l(3)72Da l(3)72Db th right 72D2-5 Df(3L)brm11 left 72D5-10 Df(3L)st-er l(3)72Dd right 72D5 Df(3L)th117 l(3)72De l(3)72Df l(3)72Dg l(3)72Dh l(3)72Di l(3)72Dj l(3)72Dk l(3)72Dl l(3)72Dm left 72D7-11 Df(3L)st4 l(3)72Dn l(3)72Do left 72D10-11 Df(3L)st-b11 l(3)72Dp right 72D12 Df(3L)th102 # l(3)73 Two groups active in inducing mutations in this region; McKeown and Belote in their studies of tra, and Hoffman in his investigation of Abl (Belote, Hoffmann, McKeown, Chorsky, and Baker, 1990, Genetics 125: 783-93). genetic cytological locus location location included in excluded from synonym _________________________________________________________________________ l(3)73Aa 3-{44} 73A2-3 Df(3L)st-f13 Df(3L)st-a20 l(3)std6 l(3)73Ab 3-{44} 73A3-4 Df(3L)st-a20 l(3)133.37 Df(3L)st-f13 l(3)73Ac 3-{44} 73A4-7 Df(3L)st7P Df(3L)st-f13 l(3)std2 l(3)73Ad 3-{44} 73A4-7 Df(3L)st7P Df(3L)st-f13 l(3)std8 l(3)73Ae 3-{44} 73A4-7 Df(3L)st7P Df(3L)st-f13 l(3)std18 l(3)73Af 3-{44} 73A4-7 Df(3L)st7P Df(3L)st-f13 l(3)133.52 l(3)73Ag 3-{44} 73A4-7 Df(3L)st7P Df(3L)st-f13 l(3)133.59 l(3)73Ah 3-{44} 73A7-9 Df(3L)st-E52 Df(3L)st7P l(3)133.18 l(3)73Ai 3-{44} 73A9-10 Df(3L)st-g24 Df(3L)st-E52 l(3)DTS5 l(3)73Aj 3-{44} 73A10-B1 Df(3L)st-j7 Df(3L)st-g24 l(3)std4 l(3)73Ba 3-{44} 73A10-B1 Df(3L)st-E34 Df(3L)st-j7 Abl l(3)73Bb 3-{44} 73B1-2 Df(3L)st-E34 Df(3L)st-j7 l(3)std10 l(3)73Bc 3-{44} 73B1-5 Df(3L)std100.62 Df(3L)st-E34 l(3)std5 l(3)73Bd 3-{44} 73C1 Df(3L)st4 Df(3L)st100.62 l(3)73Be 3-{44} 73B1-5 Df(3L)st100.62 Df(3L)st4 dab l(3)73Ca 3-{44} 73C1-D2 Df(3L)st81k Df(3L)st4 l(3)73Cd 3-{44} 73C1-D2 Df(3L)st81k Df(3L)st4 allele origin discoverer synonym comments _______________________________________________________________ l(3)73Aa1 X ray Belote, McKeown l(3)std6 P, PA l(3)73Aa2 X ray Belote, McKeown l(3)std12 l(3)73Aa3 X ray Belote, McKeown l(3)std13 l(3)73Aa4 X ray Belote, McKeown l(3)std15 l(3)73Aa5 X ray Belote, McKeown l(3)std16 l(3)73Aa6 X ray Belote, McKeown l(3)std17 T(2;3)40-41; 73A2-3 l(3)73Aa7 X ray Belote, McKeown l(3)std19 l(3)73Aa8 X ray Belote, McKeown l(3)std20 l(3)73Aa9 X ray Belote, McKeown l(3)std21 l(3)73Aa10 EMS Hoffmann l(3)132.23 l(3)73Aa11 EMS Hoffmann l(3)133.36 l(3)73Aa12 EMS Hoffmann l(3)133.45 l(3)73Aa13 EMS Hoffmann l(3)133.7 l(3)73Aa14 EMS l(3)73Aa15 EMS l(3)73Ab1 EMS Hoffmann l(3)132.10 P, PA l(3)73Ab2 EMS Hoffmann l(3)133.1 l(3)73Ab3 EMS Hoffmann l(3)133.12 l(3)73Ab4 EMS Hoffmann l(3)133.37 L3 ( l(3)73Ab5 EMS Hoffmann l(3)134.22 l(3)73Ab6 EMS Hoffmann l(3)134.43 l(3)73Ab7 EMS l(3)73Ab8 EMS l(3)73Ac1 X ray Belote, McKeown l(3)std2 L l(3)73Ac2 EMS Hoffmann l(3)133.34 l(3)73Ac3 EMS l(3)73Ac4 EMS l(3)73Ac5 EMS l(3)73Ad1 X ray Belote, McKeown l(3)std8 L l(3)73Ae1 X ray Belote, McKeown l(3)std18 L l(3)73Af1 EMS Hoffmann l(3)133.52 L l(3)73Af2 EMS l(3)73Af3 EMS l(3)73Af4 EMS l(3)73Ag1 EMS Hoffmann l(3)133.59 P, PA; tergites fail to develop l(3)73Ah1 EMS Hoffmann l(3)133.18 L3, P l(3)73Ai1 EMS Suzuki l(3)DTS5 L-P; hfw-like; dominant temperature sensitive l(3)73Ai2 EMS Hoffmann l(3)133.16 L l(3)73Ai3 EMS Hoffmann l(3)133.29 L l(3)73Aj1 X ray Belote, McKeown l(3)std4 E; small deletion l(3)73Bb1 X ray Belote, McKeown l(3)std10 E; T(Y;2;3)Y; 44C2-4; 54B10-15; 73B1-2 l(3)73Bb2 EMS l(3)73Bb3 EMS l(3)73Bb4 EMS l(3)73Bc1 X ray Belote, McKeown l(3)std5 E l(3)73Bc2 EMS l(3)73Bd1 EMS l(3)73Bd2 EMS l(3)73Bd3 EMS l(3)73Ca1 EMS ( Abnormal mitosis; sex transformation in tra2/+; tra/l(3)73Ab4 females (Andrew, 1987, PhD Thesis, University of California, San Diego). | YP|54B10-44C4|54B15-60. YD|73B2-100|21-44C2|73B1-61. # DEFICIENCY MAP OF REGION 73A DNA ( side breakpoint variant coordinates __________________________________________________ 73A2-3 l(1)73Aa < -90 left 73A3 Df(3L)st-a20 -40 73A3-4 l(3)73Ab left 73A3-4 In(3LR)st-a27 0 73A3-4 st 0 right 73A3-4 Df(3L)st-f13 left 73A4 Df(3L)tra right 73A3-4 Df(3L)st-a20 right 73A5 Df(3L)st-e4 60 73A5-9 l(3)73Ac 73A5-9 l(3)73Ad 73A5-9 l(3)73Ae 73A5-9 l(3)73Af 73A5-9 l(3)73Ag right 73A7-9 Df(3L)st7P 80 73A7-10 l(3)73Ah 73A7-10 tra right 73A7-9 Df(3R)st-E52 90 l(3)73Ai 73A10-B1 mfs(3)73A right Df(3L)st-g24 105 73A10-B1 l(3)73Aj 3 Abl left 73A10-11 Df(3R)std11 right 73B1-2 Df(3R)st-E36 110 right 73B1-2 Df(3R)st-j7 140 5 Abl 73B1-2 l(3)73Bb right 73B3 Df(3L)st-E34 73B1-5 l(3)73Bc right 73B3-5 Df(3L)st62 right 73B4 Df(3L)st8P left dab right 73C1-2 Df(3L)st100;62 right dab l(3)73Bd right 73C1 Df(3L)st4 l(3)73Ca l(3)73Cd db plk right 73D1-2 Df(3L)st81k ( Coordinates in kilobases from the left breakpoint of In(3L)st-a27. # l(3)80F-81F A series of ethyl-methanesulfonate-induced lethals detected by failure to complement proximal heterochromatic deficiencies in 3L or 3R, which resulted from detachments, i.e., reconsti- tutions of normal third chromosomes, from irradiated C(3L)RM/C(3R)RM-bearing females; a large set of such proximal heterochromatic deficiencies was employed in deficiency map- ping of these lethals (Marchant and Holm, 1988, Genetics 120: 519-32). genetic locus location included in excluded from synonym ______________________________________________________ l(3)80Fa 3-{47} Df(3L)1-16 Df(3L)5-84 l(3)Lh8 l(3)80Fb 3-{47} Df(3L)5-84 Df(3L)10-58 l(3)Lh7 l(3)80Fc 3-{47} Df(3L)10-58 Df(3L)10-39 l(3)Lh6 l(3)80Fd 3-{47} Df(3L)10-39 Df(3L)8A-80 l(3)Lh5 l(3)80Fe 3-{47} Df(3L)10-39 Df(3L)8A-80 l(3)Lh5 l(3)80Ff 3-{47} Df(3L)8A-80 Df(3L)1-166 l(3)Lh4B l(3)80Fg 3-{47} Df(3L)1-166 Df(3L)2-66 l(3)Lh4A l(3)80Fh 3-{47} Df(3L)2-66 Df(3L)9-56 l(3)Lh3 l(3)80Fi 3-{47} Df(3L)9-56 Df(3L)3-9 l(3)Lh2 l(3)80Fj 3-{47} Df(3L)3-9 l(3)Lh1 l(3)81Fa 3-{47} Df(3R)10-65 l(3)Rh1 l(3)81Fb 3-{47} Df(3)4-7 Df(3R)10-65 l(3)Rh2 allele origin synonym comments ( __________________________________________________ l(3)80Fa1 EMS 1-16-2 l(3)80Fa2 EMS 1-16-10 l(3)80Fa3 EMS 1-16-30 l(3)80Fb1 EMS 1-16-29 group 1 l(3)80Fb2 EMS 1-16-36 group 2 + 3 l(3)80Fb3 EMS 1-16-37 group 1 l(3)80Fb4 EMS 1-16-38 group 2 l(3)80Fb5 EMS 1-16-40 group 1 + 2 l(3)80Fc1 EMS 1-16-18 l(3)80Fc2 EMS 1-16-28 l(3)80Fd1 EMS 1-16-16 l(3)80Fd2 EMS 1-16-19 l(3)80Fd3 EMS 1-16-26 l(3)80Fd4 EMS 1-16-34 l(3)80Fe1 EMS 1-16-27 l(3)80Ff1 EMS 1-16-4 l(3)80Ff2 EMS 1-16-7 l(3)80Ff3 EMS 1-16-8 l(3)80Ff4 EMS 1-16-11 l(3)80Ff5 EMS 1-16-12 l(3)80Ff6 EMS 1-16-13 l(3)80Ff7 EMS 1-16-17 l(3)80Ff8 EMS 1-16-20 l(3)80Ff9 EMS 1-16-21 l(3)80Ff10 EMS 1-16-22 l(3)80Ff11 EMS 1-16-23 l(3)80Ff12 EMS 1-16-24 l(3)80Ff13 EMS 1-16-25 l(3)80Ff14 EMS 1-16-31 l(3)80Ff15 EMS 1-16-32 l(3)80Ff16 EMS 1-16-35 l(3)80Ff17 EMS 1-16-41 l(3)80Ff18 EMS 1-16-43 l(3)80Ff19 EMS 1-16-44 l(3)80Ff20 EMS 1-16-45 l(3)80Fg1 EMS 1-16-15 l(3)80Fg2 EMS 1-16-42 l(3)80Fg3 EMS 1-166-5 heat-sensitive allele l(3)80Fg4 EMS 1-166-8 l(3)80Fg5 EMS 1-166-9 l(3)80Fg6 EMS 1-166-14 l(3)80Fg7 EMS 1-166-18 l(3)80Fg8 EMS 1-166-26 l(3)80Fg9 EMS 1-166-32 l(3)80Fg10 EMS 1-166-44 l(3)80Fh1 EMS 1-166-38 l(3)80Fh2 EMS 1-166-39 l(3)80Fi1 EMS 1-166-13 l(3)80Fi2 EMS 1-166-33 l(3)80Fi3 EMS 1-166-37 l(3)80Fj1 EMS 1-166-1 l(3)80Fj2 EMS 1-166-2 l(3)80Fj3 EMS 1-166-3 l(3)80Fj4 EMS 1-166-22 l(3)80Fj5 EMS 1-166-27 l(3)80Fj6 EMS 1-166-29 l(3)80Fj7 EMS 1-166-34 l(3)80Fj8 EMS 1-166-40 l(3)80Fj9 EMS 1-166-45 l(3)81Fa1 EMS 4-75-12 l(3)81Fa2 EMS 4-75-17 l(3)81Fa3 EMS 10-65-2 l(3)81Fa4 EMS 10-65-6 l(3)81Fb1 EMS 4-75-3 group 1 l(3)81Fb2 EMS 4-75-4 group 1 + 2 l(3)81Fb3 EMS 4-75-5 group 2 l(3)81Fb4 EMS 4-75-6 group 1 + 2 l(3)81Fb5 EMS 4-75-7 group 1 + 2 l(3)81Fb6 EMS 4-75-9 group 2 l(3)81Fb7 EMS 4-75-13 group 1 + 2 l(3)81Fb8 EMS 4-75-14 group 1 + 2 l(3)81Fb9 EMS 4-75-15 group 2 l(3)81Fb10 EMS 4-75-16 group 2 ( Complementation groups indicated for cases of interallelic complementation. # DEFICIENCY MAP OF REGION 80F side variant _________________________ left Df(3L)1-16 left Df(3L)1-104 left Df(3L)8-15 left Df(3L)9-52 l(3)80Fa left Df(3L)2-85 left Df(3L)3-52 left Df(3L)5-84 l(3)80Fb left Df(3L)10-58 left Df(3L)10-33 l(3)80Fc left Df(3L)1-17 left Df(3L)3-10 left Df(3L)3-109 left Df(3L)3-135 left Df(3L)3-164 left Df(3L)4-134 left Df(3L)6-53 left Df(3L)6-61 left Df(3L)8-68 left Df(3L)9-2 left Df(3L)9-7 left Df(3L)10-14 left Df(3L)10-39 left Df(3L)10-210 left Df(3L)12-2 left Df(3L)12-123 right Df(3L)10-33 l(3)80Fd l(3)80Fe left Df(3L)4A-6 left Df(3L)6-21 left Df(3L)8A-80 left Df(3L)9-37 left Df(3L)10-26 left Df(3L)10-109 right Df(3L)1-104 right Df(3L)2-85 right Df(3L)3-109 right Df(3L)3-164 right Df(3L)5-84 right Df(3L)6-53 right Df(3L)6-61 right Df(3L)9-2 right Df(3L)9-7 right Df(3L)9-52 right Df(3L)10-14 right Df(3L)10-39 right Df(3L)10-210 right Df(3L)12-2 right Df(3L)12-123 l(3)80Ff left Df(3L)1-166 left Df(3L)6-18 l(3)80Fg left Df(3L)1-166-12 ( left Df(3L)1-166-46 ( left Df(3L)2-66 left Df(3L)3-30 left Df(3L)4-76 left Df(3L)4-184 left Df(3L)4A-48 right Df(3L)1-16 right Df(3L)1-17 right Df(3L)3-10 right Df(3L)3-52 right Df(3L)3-135 right Df(3L)4-134 right Df(3L)4A-6 right Df(3L)8-15 right Df(3L)8-68 right Df(3L)8A-80 right Df(3L)10-26 right Df(3L)10-58 right Df(3L)10-109 l(3)80Fh left Df(3L)9-10 left Df(3L)9-56 right Df(3L)3-30 l(3)80Fi left Df(3L)2-30 left Df(3L)3-9 left Df(3L)8A-49 left Df(3L)10-39 right Df(3L)1-166-12 ( right Df(3L)4-76 right Df(3L)4-184 right Df(3L)4A-48 l(3)80Fj right Df(3L)1-166 right Df(3L)1-166-46 ( right Df(3L)2-30 right Df(3L)2-66 right Df(3L)3-9 right Df(3L)8A-49 right Df(3L)9-10 right Df(3L)9-56 right Df(3L)10-39 CENTROMERE left Df(3R)4-75 left Df(3R)4-75-08 ( left Df(3R)5-53 left Df(3R)7-53 left Df(3R)7-93 left Df(3R)10-65 left Df(3R)10-73 left Df(3R)10-120 left Df(3R)12-68 left Df(3R)12-122 l(3)81Fa right Df(3R)7-53 right Df(3R)7-93 right Df(3R)10-65 right Df(3R)10-73 right Df(3R)10-120 right Df(3R)12-68 right Df(3R)12-122 l(3)81Fb right Df(3R)4-75 right Df(3R)4-75-08 ( right Df(3R)5-53 ( Deletions induced in normal third chromosomes with ethyl methanesulfonate. # l(3)84 Comprised primarily of components of the Antennapedia Com- plex, ANTC. genetic cytological locus location location included in excluded from synonym _________________________________________________________________ l(3)84Aa 3-{47} 84A1-6 Df(3R)Scr Df(3R)Antp17 twr l(3)84Ab 3-{47} 84A1-6 Df(3R)Scr Df(3R)Antp17 cel l(3)84Ac 3-{47} 84A1-6 Df(3R)Scr Df(3R)Antp17 lab l(3)84Ad 3-{47} 84A1-6 Df(3R)Scr Df(3R)Antp17 zen l(3)84Ae 3-47.5 84A6-B1 Df(3R)Scr Df(3R)Hu Dfd Df(3R)Antp17 l(3)84Af 3-47.5 84A6-B1 Df(3R)Scr Scr Df(3R)Antp17 l(3)84Ag 3-47.5 84A6-B1 Df(3R)Scr Df(3R)Hu ftz Df(3R)Antp17 # l(3)84Ab phenotype: Cell lethal; dies as normal-appearing second instar larva. references: Lewis, Wakimoto, Denell, and Kaufman, 1980, Genet- ics 95: 367-81. alleles: allele origin discoverer synonym _____________________________________ l(3)84Ab1 EMS Wakimoto EfW1 l(3)84Ab2 EMS Wakimoto EfW14 l(3)84Ab3 X ray Abbot a12 l(3)84Ab4 EMS Lambert c29 l(3)84Ab5 EMS Lambert c59 l(3)84Ab6 EMS Fornili f32 l(3)84Ab7 EMS Fornili f35 l(3)84Ab8 EMS Fornili f39 l(3)84Ab9 EMS Fornili f44 l(3)84Ab10 EMS Fornili f45 l(3)84Ab11 EMS Fornili f67 l(3)84Ab12 EMS Fornili f72 l(3)84Ab13 EMS Fornili f77 l(3)84Ab14 X ray Lopez L5 l(3)84Ab15 EMS Merrill V11 # l(3)84B-C The region within Df(3R)Antp17; subjected to eight satura- tion mutagenesis experiments; mutants recovered subject to deficiency and complementation mapping. references: Lewis, Kaufman, Denell, and Tallerico, 1980, Genet- ics 95: 367-81. Cavener, Otteson, and Kaufman, 1986, Genetics 114: 111-23. genetic cytological locus location location included in excluded from synonym __________________________________________________________________ l(3)84Ba 3-47.5 84B1-2 Df(3R)A41 Antp Df(3R)A3 l(3)84Bb 3-{47} 84B2-C2 Df(3R)30c76 Df(3R)Scr l(3)84Bc 3-{47} 84B2-C2 Df(3R)Win3 Df(3R)30c76 l(3)84Bd 3-47.8 84B2-C2 Df(3R)Scx2 Df(3R)Win3 ( Tub84B l(3)84Be 3-{47} 84B2-C2 Df(3R)Scx2 Df(3R)Win3 stk allele origin discoverer synonym ____________________________________ l(3)84Bb1 EMS Denell l(3)d5 l(3)84Bb2 EMS Kaufman l(3)k3 l(3)84Bb3 EMS Kaufman l(3)k12 l(3)84Bb4 EMS R. Lewis l(3)r7 l(3)84Bb5 EMS R. Lewis l(3)r10 l(3)84Bb6 EMS R. Lewis l(3)r15 l(3)84Bc1 EMS R. Lewis l(3)r14 genetic cytological locus location location included in excluded from synonym _________________________________________________________________ l(3)84Ca 3-{47} 84C1-6 Df(3R)Antp1 Df(3R)Scx2 hat l(3)84Cb 3-{47} 84C1-6 Df(3R)Antp1 Df(3R)Scx2 l(3)84Cc 3-{47} 84C1-6 Df(3R)Antp1 Df(3R)Scx2 l(3)84Cd 3-{47} 84C1-6 Df(3R)Antp1 Df(3R)Scx2 sas l(3)84Ce 3-{47} 84C5-8 Df(3R)A40 Df(3R)Antp1 Df(3R)dsx29 l(3)84Cf 3-{47} 84C5-8 Df(3R)A40 Df(3R)Antp1 ted Df(3R)dsx29 l(3)84Cg 3-48 84C8-D1 Df(3R)dsx29 Df(3R)D6 Gld # l(3)84Cb phenotype: Pupal lethal. allele origin discoverer synonym ref ( comments ___________________________________________________________________ l(3)84Cb1 EMS Cavener l(3)g6 1 complements l(3)84Cb3 l(3)84Cb2 EMS R. Lewis l(3)r8 1 non-complementing allele l(3)84Cb3 EMS R. Lewis l(3)r15 1 complements l(3)84Cb1 ( 1 = Cavener, Otteson, and Kaufman, 1986, Genetics 114: 111-23. # l(3)84Cc phenotype: Pupal lethal. allele origin discoverer synonym ref ( __________________________________________ l(3)84Cc1 EMS Cavener l(3)g4 1 l(3)84Cc2 EMS l(3)k9 1 l(3)84Cc3 EMS R. Lewis l(3)r6 1 ( 1 = Cavener, Otteson, and Kaufman, 1986, Genetics 114: 111-23. # l(3)84Ce phenotype: l(3)84Ce1 partially complements both l(3)84Ce2 and Df(3R)dsx2; l(3)84Ce1/Df(3R)dsx2 eclose successfully, but can- not fly or walk normally. l(3)84Ce2/Df(3R)Scx4 exhibit half- out phenotype characteristic of hat. allele origin discoverer synonym ref ( comments ____________________________________________________________________________ l(3)84Ce1 EMS Grigliatti l(3)2.1 1 partially complements l(3)84Ce2 l(3)84Ce2 EMS Kaufman l(3)k2 1 ( 1 = Cavener, Otteson, and Kaufman, 1986, Genetics 114: 111-23. # l(3)84D-F The region within Df(3R)dsx2D subjected to saturation mutagenesis with ethyl methanesulfonate by Baker, Hoff, Kauf- man, Wolfner, and Hazelrigg (Genetics, in press). genetic cytological locus location location included in excluded from _________________________________________________________ l(3)84Da 3-{48} 84D11-12 Df(3R)dsx2D Df(3R)10D l(3)84Db 3-{48} 84D13-14 Df(3R)dsx43 Df(3R)Antp17 l(3)84Dc 3-{48} 84D13-14 Df(3R)dsx43 Df(3R)Antp17 l(3)84Dd 3-{48} 84D13-14 Df(3R)dsx43 Df(3R)Antp17 # l(3)84Da phenotype: Hemizygotes for l(3)84Da1 semilethal when the test deficiency extends distally as far as 84F6-7 [e.g. Df(3R)dsx29] and lethal when the deficiency extends as far as 84F16 [e.g. Df(3R)dsx2D]. l(3)84Da2 not extensively tested for this behavior. alleles: allele synonym ___________________ l(3)84Da1 k5 l(3)84Da2 k21 l(3)84Db1 bD10 l(3)84Db2 bR24 l(3)84Db3 cK1 l(3)84Db4 dK4 l(3)84Db5 dR9 l(3)84Db6 dR11 l(3)84Db7 dR23 l(3)84Db8 H7 l(3)84Db9 H23 l(3)84Db10 Ns+R72 l(3)84Dc1 bR4 l(3)84Dc2 bR14 l(3)84Dc3 cK3 l(3)84Dc4 K25 l(3)84Dd1 H34 # l(3)84E genetic cytological locus location location included in excluded from _________________________________________________________ l(3)84Ea 3-{48} 84E1-8 Df(3R)dsx43 Df(3R)dsx2M l(3)84Eb 3-{48} 84E1-8 Df(3R)dsx43 Df(3R)dsx2M l(3)84Ec 3-{48} 84E6-9 Df(3R)dsx21 Df(3R)dsx43 l(3)84Ed 3-{48} 84E6-9 Df(3R)dsx21 Df(3R)dsx43 l(3)84Ee 3-{48} 84E6-9 Df(3R)dsx21 Df(3R)dsx43 l(3)84Ef 3-{48} 84E8-9 Df(3R)dsx21 Df(3R)p40 l(3)84Eg 3-{48} 84E8-9 Df(3R)dsx21 Df(3R)p40 l(3)84Eh 3-{48} 84E8-F1 Df(3R)p40 Df(3R)p13 l(3)84Ei 3-{48} 84E8-F1 Df(3R)p40 Df(3R)p13 allele synonym ________________ l(3)Ea1 H5 l(3)Ea2 H18 l(3)Ea3 H38 l(3)Ea4 H56 l(3)Eb1 Es l(3)Eb2 H4 l(3)Eb3 H20 l(3)Eb4 K2 l(3)Ec1 H8 l(3)Ed1 H13 l(3)Ee1 H60 l(3)Ef1 bR5 l(3)Ef2 H36 l(3)Ef3 K1 l(3)Eg1 H l(3)Eg2 223 l(3)Eg3 H12 l(3)Eg4 H19 l(3)Eg5 H24 l(3)Eg6 H61 l(3)Eg7 K41 l(3)Eh1 K10 l(3)Eh2 K19 l(3)Eh3 K36 l(3)Ei1 K40 # l(3)84F genetic cytological locus location location included in excluded from _________________________________________________________ l(3)84Fa 3-{48} 84F1-2 Df(3R)p13 Df(3R)dsx10M l(3)84Fb 3-{48} 84F1-2 Df(3R)dsx3 Df(3R)dsx10M l(3)84Fc 3-{48} 84F1-2 Df(3R)dsx3 Df(3R)dsx10M l(3)84Fd 3-{48} 84F1-2 Df(3R)D7 Df(3R)dsx3 l(3)84Fe 3-{48} 84F1-7 Df(3R)dsx29 Df(3R)10M l(3)84Ff 3-{48} 84F1-7 Df(3R)dsx29 Df(3R)D7 l(3)84Fg 3-{48} 84F1-7 Df(3R)dsx29 Df(3R)D7 l(3)84Fh 3-{48} 84F10-16 Df(3R)p30 Df(3R)D6 l(3)84Fi 3-{48} 84F10-16 Df(3R)p30 Df(3R)D6 l(3)84Fj 3-{48} 84F10-16 Df(3R)p30 Df(3R)D6 l(3)84Fk 3-{48} 84F13-16 Df(3R)2D Df(3R)D6 l(3)84Fl 3-{48} 84F13-16 Df(3R)2D Df(3R)D6 l(3)84Fm 3-{48} 84F13-16 Df(3R)2D Df(3R)D6 allele synonym __________________ l(3)84Fa1 H10 l(3)84Fa2 K18 l(3)84Fb1 H27 l(3)84Fb2 H28 l(3)84Fb3 H44 l(3)84Fc1 H40 l(3)84Fd1 K9 l(3)84Fd2 K13 l(3)84Fd3 K38 l(3)84Fe1 H17 l(3)84Ff1 H11 l(3)84Ff2 H57 l(3)84Fh1 K23 l(3)84Fi1 K29 l(3)84Fj1 dR1 l(3)84Fj2 H15 l(3)84Fk1 H2 l(3)84Fk2 H33 l(3)84Fl1 dK13 l(3)84Fm1 434.12 l(3)84Fm2 H37 l(3)84Fm3 K3 # DEFICIENCY MAP OF REGION 84 side breakpoint variant ________________________________________________ left 84A4-5 Df(3R)Antp3 left 84A4-5 Df(3R)Antp4 left 84A1-2 Df(3R)Scr 84A1-6 twr 84A1-6 l(3)84Ab 84A1-6 lab left 84A4-5 Df(3R)Scx2 84A4-6 bcd 84A4-6 pb 84A1-6 zen left Df(3R)29c76+Dp(3;3)Dfdrv1 left Df(3R)30c76+Dp(3;3)Dfdrv1 left 84A6 Df(3R)Antp17 84A6-B1 Dfd right 84A6-B1 Df(3R)26b77+Dp(3;3)Dfdrv1 84A6-B1 Scr right 84A4-5 Df(3R)29c76+Dp(3;3)Dfdrv1 84A6-B1 ftz left 84B1-2 Df(3R)A41 5 84B1-2 Antp left Df(3R)A60 left Df(3R)IP right Df(3R)Scr left Df(3R)A75 left Df(3R)BDR3 right Df(3R)1274 3 Antp right 84B1-2 Df(3R)Antp3 right 84B1-2 Df(3R)Antp4 right 84B1-2 Df(3R)30c76+Dp(3;3)Dfdrv1 right 84B2-3 Df(3R)Antp73a 84B3 l(3)84Ba right 84B3-6 Df(3R)30c76 84B3 l(3)84Bb right 84B1-2 Df(3R)Win3 84B1-2 ( Tub84B mab left T(2;3)Ta1 stk left 84C1-2 Df(3R)Antp1 left 84C1-2 Df(3R)dsx2Ma right 84B1-2 Df(3R)Scx2a 84C1-6 hat right T(2;3)TaL 84C1-6 l(3)84Cb 84C1-6 l(3)84Cc 84C1-6 rue 84C1-6 sas right 84C5-6 Df(3R)Antp73b 84C5-8 l(3)84Ce 84C5-8 ted left 84C8-D1 Df(3R)dsx29 84C8-D1 Gld right 84D1-2 Df(3R)A41 left 84D2-3 Df(3R)D6 roe left 84D3 Df(3R)dsx10M rn Est-C left 84D5 Df(3R)D7 left 84D8-9 Df(3R)dsx11 left 84D11 Df(3R)dsx2D left 84D11-12 Df(3R)dsx21 l(3)84Da left 84D11-12 Df(3R)dsx10D left 84D10-11 Df(3R)dsx15 left 84D11-14 Df(3R)dsx3 left 84D13-14 Df(3R)dsx43 l(3)84Db l(3)84Dc l(3)84Dd right 84D13-14 Df(3R)Antp17 right 84E1-2 Df(3R)dsx2M dsx l(3)84Ea l(3)84Eb right 84E6-8 Df(3R)dsx43 right 84E8 Df(3R)dsx15 l(3)84Ec l(3)84Ed l(3)84Ee right 84E8-9 Df(3R)dsx21 l(3)84Ef l(3)84Eg left 84E8-9 Df(3R)p40 l(3)84Eh l(3)84Ei left 84F1 Df(3R)p13 l(3)84Fa right 84F1-2 Df(3R)dsx10M l(3)84Fb l(3)84Fc right 84E12-13 Df(3R)dsx3 l(3)84Fd right 84F1-2 Df(3R)D7 l(3)84Fe l(3)84Ff l(3)84Fg right 84F6-7 Df(3R)dsx29 left 84F8-10 Df(3R)p30 l(3)84Fh l(3)84Fi l(3)84Fj right 84F13-16 Df(3R)D6 l(3)84Fk l(3)84Fl l(3)84Fm right 84F16 Df(3R)dsx2D ( Df(3R)Scx2 and Df(3R)dsx2M overlap by ten kb and the trans heterozygote is lethal. T(2;3)TaL breakpoint is in the 10 kb segment and may define a lethally mutable locus between stk and hat. # l(3)85A A series of eight lethally mutable loci, all but one of which were first recorded in a saturation mutagenesis screen of the region uncovered by Df(3R)p25 (Bender, Turner, and Kaufman, 1986, Dev. Biol. 119: 418-32). Either ethyl methanesulfonate or diepoxybutane used as the mutagenic agent. Two more loci inferred from the lethality of overlapping defi- ciencies by Jones and Rawls (1988, Genetics 120: 733-42). The right most of these loci is that of hb; the rest were pre- viously unrecorded. Deficiency analysis of Bender et al. updated by Jones and Rawls with additional deficiencies. genetic cytological locus location location included in excluded from synonym _______________________________________________________________________ l(3)85Aa 3-{48} 85A1-4 Df(3R)p25 Df(3R)dsx11 L1 l(3)85Ab 3-{48} 85A3-4 Df(3R)D8 L2 Df(3R)Dhod-G1 l(3)85Ac 3-{48} 85A6-11 Df(3R)CA4B L3 Df(3R)CA1 l(3)85Ad 3-{48} 85A6-11 Df(3R)V8 Df(3R)CA1 L4 l(3)85Ae 3-{48} 85A6-11 Df(3R)p16 Df(3R)V8 L5 l(3)85Af 3-{48} 85A6-11 Df(3R)p16 Df(3R)V8 L6 l(3)85Ag 3-{48} 85A6-11 Df(3R)Dhod-G1 Df(3R)p16 L7 l(3)85Ah 3-48 85A6-11 Df(3R)p25 Df(3R)Dhod-G1 hb, Rg-pbx l(3)85Ai 3-{48} 85A4-5 Df(3R)Dhod-G1 Df(3R)V2 l(3)85Aj 3-{48} 85A6-11 Df(3R)p5 alleles: allele ____________ l(3)85Aa1-4 l(3)85Ab1 l(3)85Ac1-7 l(3)85Ad1 l(3)85Ae1-3 l(3)85Af1-7 l(3)85Ag1-3 # l(3)85D-F A collection of lethals recovered from saturation mutagenesis screens in three different laboratories (Cheney, Matthews, and Maroni). genetic cytological locus location location included in excluded from _________________________________________________________ l(3)85Da 3-{49} 85D8-13 Df(3R)by10 Df(3R)GB104 l(3)85Db 3-{49} 85D11-12 Df(3R)GB104 Df(3R)by416 l(3)85Dc 3-{49} 85D10-14 Df(3R)by416 Df(3R)by62 l(3)85Dd 3-{49} 85D11-E3 Df(3R)by62 Df(3R)by416 l(3)85De 3-{49} 85D11-E3 Df(3R)by62 Df(3R)by416 l(3)85Df 3-{49} 85D11-E3 Df(3R)by62 Df(3R)by416 l(3)85Dg 3-{49} 85D11-E3 Df(3R)by62 Df(3R)by416 l(3)85Dh 3-{49} 85D11-E3 Df(3R)by62 Df(3R)by416 l(3)85Di 3-{49} 85D11-E3 Df(3R)by62 Df(3R)by416 l(3)85Dj 3-{49} 85D11-E3 Df(3R)by62 Df(3R)by416 alleles: allele origin discoverer synonym _____________________________________ *l(3)85Da1 X ray Maroni l(3)M7 *l(3)85Da2 X ray Maroni l(3)M13 *l(3)85Da3 X ray Maroni l(3)M16 *l(3)85Db1 X ray Maroni l(3)M1 *l(3)85Db2 X ray Maroni l(3)M10 *l(3)85Dc1 X ray Maroni l(3)M17 *l(3)85Dd1 EMS Matthews l(3)E4 *l(3)85De1 EMS Matthews l(3)E10 *l(3)85Df1 X ray Maroni l(3)M4 *l(3)85Dg1 X ray Maroni l(3)M5 *l(3)85Dh1 EMS Matthews l(3)E7 *l(3)85Dh2 X ray Maroni l(3)M6 *l(3)85Dh3 X ray Maroni l(3)M9 *l(3)85Di1 EMS Matthews l(3)E11 *l(3)85Di2 X ray Maroni l(3)M12 *l(3)85Di3 X ray Maroni l(3)M14 l(3)85Dj1 EMS Matthews l(3)32 # l(3)85E These lethals fall into two segments of 85E; order l(3)85Ec Scm l(3)85Eb l(3)85Ea established by Cheney; l(3)85Ed and l(3)85Ee placed to the left of l(3)85Ea by Matthews. Neither l(3)85Ed nor l(3)85Ee tested for complementation with l(3)85Eb. genetic cytological locus location location included in excluded from synonym _________________________________________________________________ l(3)85Ea 3-49.0 85E1-10 Df(3R)GB104 Df(3R)by416 l(3)C43 Df(3R)by62 l(3)85Eb 3-49.2 85E1-10 Df(3R)GB104 Df(3R)by416 l(3)J5 Df(3R)by62 l(3)85Ec 3-49.8 85E1-10 Df(3R)GB104 Df(3R)by416 l(3)WG89 Df(3R)by62 l(3)85Ed 3-{49} 85E1-10 Df(3R)GB104 Df(3R)by416 l(3)KM19 Df(3R)by62 l(3)85Ee 3-49 85E1-10 Df(3R)GB104 Df(3R)by416 Df(3R)by62 l(3)85Ef 3-48.5 85E1-10 Df(3R)GB104 Df(3R)by416 Scm Df(3R)by62 l(3)85Eg 3-49 85E1-10 Df(3R)GB104 Df(3R)by416 knk Df(3R)by62 l(3)85Eh 3-{49} 85E10-F1 Df(3R)by10 Df(3R)GB104 Df(3R)by62 l(3)85Ei 3-{49} 85E10-F1 Df(3R)by10 Df(3R)GB104 Df(3R)by62 l(3)85Ej 3-{49} 85E10-F1 Df(3R)by10 Df(3R)GB104 Df(3R)by62 # l(3)85Ea phenotype: l(3)85Ea1 is a heat-sensitive allele. At 20 about half the expected number of homozygotes eclose, the remainder dying as pharate adults; those that emerge are sterile, ovaries failing to mature, testes appearing morphologically normal; they also exhibit other slight abnormalities such as extra sex-comb teeth and defective wing margins. At 22 all flies die as pharate adults with greatly reduced heads, often with duplicated antennal and palpal structures. No metamor- phosis accompanies development at 25; the eye disc is virtu- ally missing, whereas the wing and haltere discs are severely hyperplastic; disc effects autonomous in transplants. Temperature-shift experiments demonstrate a temperature- sensitive period lasting from the beginning of the second instar until the end of pupation. The 24-hr pulses of 27 dur- ing development reveal that the various phenotypic conse- quences of homozygosity for this allele have different TSP's. l(3)85Ea1 wing discs used to demonstrate that extra cellular proliferation is insufficient to induce transdetermination (Shearn, Martin, Davis, and Hersperger, 1984, Dev. Biol. 106: 135-46). Density of gap junctions in hyperplastic ima- ginal wing discs markedly reduced (Ryerse and Nagel, 1984, Dev. Biol. 105: 396-403); in shift-up experiments, reduc- tion in gap junctions precedes the onset of tissue hyperplasia (Ryerse and Nagel, 1985, Wilhelm Roux's Arch. Dev. Biol. 194: 480-86). Cell death also observed in wing discs as early as twelve hours following application of restrictive temperature (Sedlak, 1986, Dev. Genet 6: 199-212). Mitosis normal (Gatti and Baker, 1989, Genes Dev. 3: 438-53). alleles: In addition to those listed below a series of P- element induced alleles recovered by Cheney. allele origin discoverer synonym ref ( _______________________________________________ l(3)85Ea1 EMS Shearn l(3)C43hs 1, 2 l(3)85Ea2 EMS Shearn l(3)RD222 l(3)85Ea3 EMS Shearn l(3)RE230 l(3)85Ea4 EMS Shearn l(3)SB610 l(3)85Ea5 EMS Shearn l(3)SE924 l(3)85Ea6 EMS Shearn l(3)SJ105 l(3)85Ea7 EMS Shearn l(3)UL163 l(3)85Ea8 EMS Shearn l(3)UO571 l(3)85Ea9 EMS Shearn l(3)VI343 l(3)85Ea10 EMS Shearn l(3)VF202 l(3)85Ea11 EMS Shearn l(3)VX267 l(3)85Ea12 EMS Shearn l(3)VY293 l(3)85Ea13 EMS Shearn l(3)WB123 l(3)85Ea14 EMS Shearn l(3)WC461 *l(3)85Ea15 EMS Matthews l(3)18 *l(3)85Ea16 EMS Matthews l(3)29 *l(3)85Ea17 EMS Matthews l(3)36 *l(3)85Ea18 EMS Matthews l(3)42 *l(3)85Ea19 EMS Matthews l(3)D1A *l(3)85Ea20 EMS Matthews l(3)E5 *l(3)85Ea21 EMS Matthews l(3)E12 *l(3)85Ea22 X ray Maroni l(3)M19 *l(3)85Ea23 X ray Maroni l(3)M20 *l(3)85Ea24 X ray Maroni l(3)M22 *l(3)85Ea25 EMS Maroni l(3)M31 *l(3)85Ea26 EMS Maroni l(3)M39 *l(3)85Ea28 EMS Maroni l(3)M43 *l(3)85Ea29 EMS Maroni l(3)M49 *l(3)85Ea30 EMS Maroni l(3)M52 *l(3)85Ea31 DEB Maroni l(3)M55 *l(3)85Ea32 DEB Maroni l(3)M64 *l(3)85Ea33 DEB Maroni l(3)M68 ( 1 = Martin, Martin, and Shearn, 1977, Dev. Biol. 55: 213-32; 2 = Shearn, Rice, Garen, and Gehring, 1971, Proc. Nat. Acad. Sci. USA 68: 2594-98. # l(3)85Eb phenotype: Lethal at prepupal stage; morphology of all imaginal discs normal. alleles: allele origin discoverer synonym ref ( ___________________________________________ l(3)85Eb1 EMS Shearn l(3)J5 2, 3 l(3)85Eb2 EMS Shearn l(3)J83 2, 3 # l(3)85Ec phenotype: Lethal at prepupal stage; morphology of all imaginal discs normal. alleles: allele origin discoverer synonym ref ( comments ________________________________________________________________ l(3)85Ec1 EMS Shearn l(3)WG89 1 l(3)85Ec2 EMS Matthews l(3)KM12 l(3)85Ec3 DEB Matthews l(3)D1B l(3)85Ed1 EMS Maroni l(3)M36 l(3)85Ed2 EMS Maroni l(3)M56 l(3)85Ed3 EMS Maroni l(3)M58 l(3)85Ed4 EMS Maroni l(3)M63 l(3)85Ee1 EMS Matthews l(3)KM19 l(3)85Ee2 EMS Matthews l(3)104 l(3)85Ee3 EMS Matthews l(3)107 l(3)85Ee4 EMS Matthews l(3)113 l(3)85Ee5 EMS Matthews l(3)117 l(3)85Ee6 DEB Maroni l(3)M62 l(3)85Eh1 l(3)3 l(3)85Ei1 l(3)E43 l(3)85Ej1 l(3)M2 noncomplementing l(3)85Ej2 l(3)M8 complements l(3)M15 l(3)85Ej3 l(3)M15 complements l(3)M8 ( 1 = Shearn, Rice, Garen, and Gehring, 1971, Proc. Nat. Acad. Sci. USA 68: 2594-98. # l(3)85F A group of as many as eight and as few as four lethal com- plementation groups located in the region uncovered by Df(3R)by62 but not Df(3R)by10. Complementation analysis incomplete; l(3)85Fa through l(3)85Fd tested inter se; l(3)85Fe through l(3)85Fh not tested against the first four loci and incompletely tested inter se. genetic cytological locus location location included in excluded from ________________________________________________________ l(3)85Fa 3-{49} 85E15-F6 Df(3R)by62 Df(3R)by10 l(3)85Fb 3-{49} 85E15-F6 Df(3R)by62 Df(3R)by10 l(3)85Fc 3-{49} 85E15-F6 Df(3R)by62 Df(3R)by10 l(3)85Fd 3-{49} 85E15-F6 Df(3R)by62 Df(3R)by10 l(3)85Fe 3-{49} 85E15-F6 Df(3R)by62 Df(3R)by10 l(3)85Ff 3-{49} 85E15-F6 Df(3R)by62 Df(3R)by10 l(3)85Fg 3-{49} 85E15-F6 Df(3R)by62 Df(3R)by10 l(3)85Fh 3-{49} 85E15-F6 Df(3R)by62 Df(3R)by10 alleles: allele origin discoverer synonym comments __________________________________________________________ *l(3)85Fa1 EMS Matthews l(3)1 *l(3)85Fb1 EMS Matthews l(3)11 *l(3)85Fb2 EMS Matthews l(3)26 *l(3)85Fc1 EMS Matthews l(3)15 *l(3)85Fc2 EMS Matthews l(3)16 *l(3)85Fd1 EMS Matthews l(3)35 *l(3)85Fe1 EMS Matthews l(3)40 complements l(3)85Fh *l(3)85Ff1 EMS Matthews l(3)106 complements l(3)85Fg *l(3)85Fg1 EMS Matthews l(3)108 complements l(3)85Ff *l(3)85Fh1 EMS Matthews l(3)111 complements l(3)85Fe # DEFICIENCY MAP OF REGION 85 side breakpoint variant DNA coordinates ( ________________________________________________________ left 84E12-13 Df(3R)CA1 left 84D8-9 Df(3R)dsx11 left 84E6-9 Df(3R)V2 left 84F2-6 Df(3R)CA3 l(3)84Fk l(3)84Fm right 85A1-2 Df(3R)dsx11 left 85A5-7 Df(3R)p25 l(3)85Aa right 85A2-4 Df(3R)D8 -57 kb right 85A4-5 Df(3R)V5 l(3)85Ab left 84A4-5 Df(3R)Dhod-G1 -49 kb l(3)85Ai | Dhod +14 kb right 85A3-5 Df(3R)V2 +19 kb left 85A6-11 Df(3R)CA4B +22 kb left Df(3R)p5 +24 kb left Df(3R)p16 +24 kb left Df(3R)p19 +24 kb l(3)85Aj | p right Df(3R)p5 +29 kb l(3)85Ac right 85A6-11 Df(3R)CA1 +33 kb right 85A6-11 Df(3R)CA3 +33 kb right Df(3R)p19 +33 kb l(3)85Ad right 85A6-11 Df(3R)V8 +37 kb l(3)85Ae l(3)85Af right Df(3R)p16 +45 kb l(3)85Ag right 85A6-11 Df(3R)Dhod-G1 +45 kb hb +60 kb right 85A11 Df(3R)p25 +60 kb right 85C3-6 Df(3R)CA4B left 85D3-5 Df(3R)D8 left 85D8-12 Df(3R)by10 l(3)85Da left 85D11-13 Df(3R)GB104 l(3)85Db left 85D10-12 Df(3R)by416 l(3)85Dc left 85D11-14 Df(3R)by62 l(3)85Dd l(3)85De l(3)85Df l(3)85Dg l(3)85Dh l(3)85Di l(3)85Dj right 85E1-3 Df(3R)by416 l(3)85Ec Scm l(3)85Eb l(3)85Ed l(3)85Ee l(3)85Ea knk ( Tub85E right 85E10 Df(3R)GB104 l(3)85Eg l(3)85Eh l(3)85Ei right 85E7-F1 Df(3R)by10 l(3)85Fa l(3)85Fb l(3)85Fc l(3)85Fd l(3)85Fe l(3)85Ff l(3)85Fg l(3)85Fh right 85F16 Df(3R)by62 ( Approximate coordinates of Jones and Rawls (1988, Genetics 120: 733-42). # l(3)86F Seven lethally mutable loci identified by saturation mutagenesis studies of Gausz, Gyurkovics, Bencze, Awad, Hol- den, and Ish-Horowicz (1981, Genetics 98: 775-89). genetic cytological locus location location included in excluded from synonym _________________________________________________________________________ l(3)86Fa 3-{51} 86F1-7 Df(3R)T07 l(3)ck1 l(3)86Fb 3-{51} 86F1-7 Df(3R)T07 l(3)ck2 l(3)86Fc 3-{51} 86F4-7 Df(3R)T07 l(3)ck3 Df(3R)E229 l(3)86Fd 3-{51} 86F4-7 Df(3R)T07 l(3)ck4 Df(3R)E229 l(3)86Fe 3-{51} 86F6-87A2 Df(3R)E229 Df(3R)kar-H5 l(3)ck5 l(3)86Ff 3-{51} 86F6-87A2 Df(3R)E229 Df(3R)kar-H5 l(3)ck6 l(3)86Fg 3-{51} 86F6-87A2 Df(3R)E229 Df(3R)kar-H5 l(3)ck7 # l(3)86Fa phenotype: Hemizygous lethal; lethal phase in first and second larval instars. Intragenic complementation seen in some heteroallelic combinations; l(3)86Fa1/l(3)86Fa2 survivors exhibit low viability; adults weak with poor cuticular pigmen- tation and abnormal wings. references: Gausz, Gyurkovics, Bencze, Awad, Holden, and Ish- Horowicz, 1981, Genetics 98: 775-89. alleles: allele origin synonym ______________________________ l(3)86Fa1 EMS ck1e70 l(3)86Fa2 EMS ck1e143 l(3)86Fa3 EMS ck1e199 l(3)86Fa4 EMS ck1e264 l(3)86Fa5 EMS ck1nf20 l(3)86Fa6 EMS ck1hs9 # l(3)86Fb phenotype: Hemizygotes die as second or third instar larvae; larvae leave medium and die. references: Gausz, Gyurkovics, Bencze, Awad, Holden, and Ish- Horowicz, 1981, Genetics 98: 775-89. alleles: allele origin synonym comments ________________________________________ l(3)86Fb1 EMS ck2e2 L2 l(3)86Fb2 EMS ck2e144 L2-3 l(3)86Fb3 EMS ck2e202 l(3)86Fb4 EMS ck2e253 l(3)86Fb5 EMS ck2nf38 # l(3)86Fc phenotype: Hemizygotes surviving to adulthood exhibit abnormal morphology. references: Gausz, Gyurkovics, Bencze, Awad, Holden, and Ish- Horowicz, 1981, Genetics 98: 775-89. Reuter, Gausz, Gyurkovics, Friede, Bang, Spierer, Hall, and Spierer, 1987, Mol. Gen. Genet. 210: 429-36. phenotype: Fails to complement lethality of Su(var)3-13; how- ever, l(3)86Fc4 and l(3)86Fc5 have no dominant variegation suppressing effects (Reuter et al.). alleles: allele origin synonym comments _______________________________________ l(3)86Fc1 EMS ck3e27 P l(3)86Fc2 EMS ck3e29 l(3)86Fc3 EMS ck3e51 l(3)86Fc4 EMS ck3e277 P-A l(3)86Fc5 EMS ck3e297 l(3)86Fc6 EMS ck3hs18 l(3)86Fd1 EMS ck4e243 E-L-P l(3)86Fe1 EMS ck5e88 L1-2 l(3)86Fe2 X ray ck5t19 l(3)86Fe3 EMS ck5b221 l(3)86Fe4 EMS ck5b262 l(3)86Ff1 EMS ck6e145 L1-2 l(3)86Ff2 X ray ck6t07 # l(3)86Fg phenotype: Hemizygous larvae have uninflated tracheae. references: Gausz, Gyurkovics, Bencze, Awad, Holden, and Ish- Horowicz, 1981, Genetics 98: 775-89. alleles: allele origin synonym comments _______________________________________ l(3)86Fg1 EMS ck7nf12 L1 l(3)86Fg2 EMS ck7nf16 L1 # DEFICIENCY MAP OF REGION 86F side breakpoint variant ___________________________________ left 86E Df(3R)T45 left 86E2-4 Df(3R)T32 left 86E16-18 Df(3R)kar-D3 left 86F1-2 Df(3R)E079 left 86F1-2 Df(3R)T07 left 86F2-4 (1-2) Df(3R)T10 left 86F1-2 Df(3R)T41 left 86F1-2 Df(3R)T47 86F1-7 l(3)86Fa 86F1-7 l(3)86Fb left 86F1-2 Df(3R)T55 left 86F1-2 Df(3R)T61 left 86F1-2 Df(3R)T63 right 86F4-7 Df(3R)T07 86F4-7 l(3)86Fc 86F4-7 l(3)86Fd left 86F6-7 Df(3R)E229 86F6-87A2 l(3)86Fe 86F6-87A2 l(3)86Ff 86F6-87A2 l(3)86Fg left 87A1-2 Df(3R)kar-H5 # l(3)87 Three different studies have identified forty lethally- mutable loci in 87A-E. 87A and 87B with five and thirteen loci respectively (Gausz, Gyurkovics, Bencze, Awad, Holden, and Ish-Horowicz, 1981, Genetics 98: 775-89); 87C with four loci (Gausz, Bencze, Gyurkovics, Ashburner, Ish-Horowicz, and Holden, 1979, Genetics 93: 917-34); and 87D and E with seven and eleven loci respectively (Hilliker, Clark, and Chovnick, l980, Genetics 95: 95-110). Included among these loci are pic in 87D and Ace in 87E. # l(3)87A genetic cytological locus location location included in excluded from synonym ___________________________________________________________________________ l(3)87Aa 3-{51} 87A1-7 Df(3R)kar-H5 Df(3R)kar1W l(3)ck8 l(3)87Ab 3-{51} 87A1-7 Df(3R)kar-H5 Df(3R)kar1W l(3)ck9 l(3)87Ac 3-{51} 87A7-9 Df(3R)kar-D1 l(3)ck10 Df(3R)T47 l(3)87Ad 3-{51} 87A9-B2 Df(3R)E229 Df(3R)T47 l(3)ck11 l(3)87Ae 3-{51} 87A9-B2 Df(3R)E229 Df(3R)T47 l(3)ck12 # l(3)87Aa-Ab phenotype: Hemizygotes for l(3)87Aa3 form tanned pseudopupae in late third instar. references: Gausz, Gyurkovics, Bencze, Awad, Holden, and Ish- Horowicz, 1981, Genetics 98: 775-89. allele origin synonym comments ___________________________________________ l(3)87Aa1 EMS ck8e210 L3 l(3)87Aa2 EMS ck8e212 l(3)87Aa3 EMS ck8e296 L3 l(3)87Aa4 EMS ck8a1 l(3)87Aa5 EMS ck8a2 l(3)87Aa6 EMS ck8a3 l(3)87Aa7 EMS ck8a6 l(3)87Aa8 EMS ck8nf15 l(3)87Aa9 EMS ck8hs7 l(3)87Aa10 EMS ck8hs15 l(3)87Aa11 EMS ck8hs17 l(3)87Aa12 EMS ck8hs32 l(3)87Ab1 EMS ck9e42 l(3)87Ab2 EMS ck9e47 l(3)87Ab3 EMS ck9e82 E l(3)87Ab4 EMS ck9e110 semilethal l(3)87Ab5 EMS ck9e259 l(3)87Ab6 EMS ck9e260 E l(3)87Ab7 EMS ck9a4 l(3)87Ab8 EMS ck9nf9 l(3)87Ab9 EMS ck9nf11 l(3)87Ab10 EMS ck9hs20 # l(3)87Ac phenotype: Hemizygotes pupate but form longer-than-normal pupae. references: Gausz, Gyurkovics, Bencze, Awad, Holden, and Ish- Horowicz, 1981, Genetics 98: 775-89. allele origin synonym comments __________________________________________ l(3)87Ac1 EMS ck10e132 semilethal l(3)87Ac2 EMS ck10e160 l(3)87Ac3 EMS ck10e170 l(3)87Ac4 EMS ck10e200 LP l(3)87Ac5 EMS ck10e209 LP l(3)87Ac6 EMS ck10hs55 # l(3)87Ad phenotype: Hemizygotes die in late third instar; imaginal discs strongly reduced in size. references: Gausz, Gyurkovics, Bencze, Awad, Holden, and Ish- Horowicz, 1981, Genetics 98: 775-89. allele origin synonym comments _________________________________________ l(3)87Ad1 X ray ck11x02 L3 l(3)87Ad2 EMS ck11b42 l(3)87Ad3 EMS ck11b62 l(3)87Ad4 EMS ck11b284 l(3)87Ad5 EMS ck11b303 # l(3)87Ae phenotype: Hemizygotes die in late pupal stage; Malpighian tubules exhibit abnormal morphology. references: Gausz, Gyurkovics, Bencze, Awad, Holden, and Ish- Horowicz, 1981, Genetics 98: 775-89. allele origin synonym comments _____________________________________________________ l(3)87Ae1 EMS ck12e77 L-LP l(3)87Ae2 EMS ck12e177 LP, semilethal l(3)87Ae3 EMS ck12e294 l(3)87Ae4 EMS ck12nf10 l(3)87Ae5 EMS ck12hs5 l(3)87Ae6 EMS ck12hs28 l(3)87Ae7 EMS ck12hs41 l(3)87Ae8 EMS ck12hs78 temperature sensitive # l(3)87B genetic cytological locus location location included in excluded from synonym _____________________________________________________________________ l(3)87Ba 3-{51} 87B1-4 Df(3R)kar-Sz12 Df(3R)kar3Q l(3)ck13 l(3)87Bb 3-{51} 87B2-4 Df(3)kar3Q Df(3R)kar-H10 l(3)ck14 l(3)87Bc 3-{51} 87B2-4 Df(3)kar3Q Df(3R)kar-H10 l(3)ck15 l(3)87Bd 3-{51} 87B4-6 Df(3R)kar-H10 svp Df(3R)T45 l(3)ck16 l(3)87Be 3-{51} 87B5-9 Df(3R)E079 Df(3R)T45 l(3)ck17 l(3)87Bf 3-{51} 87B5-9 Df(3R)E079 Df(3R)T45 l(3)ck18 l(3)87Bg 3-{51} 87B5-9 Df(3R)E079 Df(3R)T45 l(3)ck19 l(3)87Bh 3-{51} 87B9-13 Df(3R)E079 l(3)ck20 Df(3R)ry615 l(3)87Bi 3-{51} 87B9-13 Df(3R)E079 l(3)ck21 Df(3R)ry615 l(3)87Bj 3-{51} 87B9-13 Df(3R)E079 l(3)ck22 Df(3R)ry615 l(3)87Bk 3-{51} 87B11-C1 Df(3R)ry615 Df(3R)kar3J l(3)ck23 l(3)87Bl 3-{51} 87B11-C1 Df(3R)ry615 Df(3R)kar3J l(3)ck24 l(3)87Bm 3-{51} 87B11-C1 Df(3R)ry615 Df(3R)kar3J l(3)ck25 # l(3)87Ba phenotype: Some heteroallelic combinations survive. references: Gausz, Gyurkovics, Bencze, Awad, Holden, and Ish- Horowicz, 1981, Genetics 98: 775-89. allele origin synonym comments ____________________________________________ l(3)87Ba1 EMS ck13e17 semilethal l(3)87Ba2 EMS ck13e72 l(3)87Ba3 EMS ck13e152 l(3)87Ba4 EMS ck13e233 L1-2 l(3)87Ba5 EMS ck13e248 l(3)87Ba6 EMS ck13e270 L1-2 l(3)87Ba7 EMS ck13nf31 l(3)87Ba8 EMS ck13hs56 l(3)87Bb1 EMS ck14e139 L1-2 l(3)87Bb2 EMS ck14hs2 l(3)87Bc1 EMS ck15e61 L1-2 l(3)87Bc2 EMS ck15e298 L1-2 l(3)87Bc3 EMS ck15nf18 l(3)87Bc4 EMS ck15nf28 l(3)87Bc5 EMS ck15hs11 l(3)87Bc6 EMS ck15hs12 l(3)87Bc7 EMS ck15hs29 l(3)87Bc8 EMS ck15hs38 l(3)87Be1 EMS ck17e8 l(3)87Be2 EMS ck17e26 L1-2 l(3)87Be3 EMS ck17e74 l(3)87Be4 EMS ck17e180 L1-3 l(3)87Be5 EMS ck17e228 l(3)87Be6 EMS ck17e249 l(3)87Be7 EMS ck17e280 l(3)87Be8 EMS ck17e281 l(3)87Be9 EMS ck17nf8 l(3)87Be10 EMS ck17nf14 l(3)87Be11 EMS ck17nf17 l(3)87Be12 EMS ck17nf25 l(3)87Be13 EMS ck17hs6 l(3)87Be14 EMS ck17hs31 # l(3)87Bf phenotype: Young hemizygous pupae undergo autolysis. references: Gausz, Gyurkovics, Bencze, Awad, Holden, and Ish- Horowicz, 1981, Genetics 98: 775-89. allele origin synonym comments ______________________________________________________ l(3)87Bf1 EMS ck18e227 l(3)87Bf2 EMS ck18e290 EP l(3)87Bf3 EMS ck18e312 EP l(3)87Bf4 EMS ck18hs44 l(3)87Bf5 EMS ck18hs71 temperature sensitive # l(3)87Bg phenotype: Hemizygotes for l(3)87Bg2 form fully-pigmented pharate adults. Viability reduced in certain trans heterozy- gotes with Su(var)3-61; several l(3)87Bg/+ genotypes suppress position-effect variegation (Reuter et al.). references: Gausz, Gyurkovics, Bencze, Awad, Holden, and Ish- Horowicz, 1981, Genetics 98: 775-89. Reuter, Gausz, Gyurkovics, Friede, Bang, Spierer, Hall, and Spierer, 1987, Mol. Gen. Genet. 210: 429-36. allele origin synonym comments _____________________________________________________ l(3)87Bg1 EMS ck19e78 dominant suppressor of variegation l(3)87Bg2 EMS ck19e168 LP l(3)87Bg3 EMS ck19e211 L2-3 l(3)87Bg4 EMS ck19e241 semilethal l(3)87Bg5 EMS ck19hs16 l(3)87Bg6 EMS ck19hs46 l(3)87Bh1 EMS ck20e9 L1-2 l(3)87Bh2 EMS ck20e214 L1-2 l(3)87Bi2 EMS ck21hs48 l(3)87Bj1 EMS ck22e186 L2-3 l(3)87Bj2 EMS ck22e293 L1-2 l(3)87Bj3 EMS ck22nf4 l(3)87Bj4 EMS ck22nf19 l(3)87Bj5 EMS ck22nf30 l(3)87Bj6 EMS ck22nf37 l(3)87Bk1 EMS ck23e67 l(3)87Bk2 EMS ck23e115 L1-2 l(3)87Bk3 EMS ck23e158 L1-3 l(3)87Bk4 EMS ck23e162 # l(3)87Bl phenotype: Young hemizygous pupae undergo autolysis. references: Gausz, Gyurkovics, Bencze, Awad, Holden, and Ish- Horowicz, 1981, Genetics 98: 775-89. allele origin synonym comments _________________________________________ l(3)87Bl1 EMS ck24e33 EP l(3)87Bl2 EMS ck24e100 EP l(3)87Bl3 EMS ck24e149 l(3)87Bl4 EMS ck24nf23 l(3)87Bl5 EMS ck24hs23 l(3)87Bl6 EMS ck24hs45 l(3)87Bm1 EMS ck25e11 l(3)87Bm2 EMS ck25e99 L1-3 l(3)87Bm3 EMS ck25e208 l(3)87Bm4 EMS ck25e219 L1-3 l(3)87Bm5 EMS ck25e318 l(3)87Bm6 EMS ck25hs13 l(3)87Bm7 EMS ck25hs25 l(3)87Bm8 EMS ck25hs37 l(3)87Bm9 EMS ck25hs52 # l(3)87C genetic cytological locus location location included in excluded from synonym ______________________________________________________________________ l(3)87Ca 3-51.7 87C4-5 Df(3R)kar-Sz29 Df(3R)kar-Sz3 l(3)SzA l(3)87Cb 3-{52} 87C6 Df(3R)T10 Df(3R)kar-SZ31 l(3)SzB l(3)87Cc 3-{52} 87C8 Df(3R)kar-Sz27 Df(3R)kar-Sz11 l(3)SzC l(3)87Cd 3-{52} 87C9 Df(3R)kar3J Df(3R)kar-Sz21 l(3)SzD # l(3)87Ca phenotype: Most extreme hemizygous phenotype is embryonic lethality, even though homozygous Df(3R)kar3J, which lacks the locus entirely, dies during the first larval instar (Ish- Horowicz, Holden, and Gehring, 1977, Cell 12: 643-52). First instar larvae have transparent Malpighian tubules; autonomous in transplants. Two alleles isolated on the basis of their dominant suppression of ectopic sex-comb teeth in Pc4/+ males (Kennison and Tamkun, 1988, Proc. Nat. Acad. Sci. USA 85: 8136-40). references: Gausz, Bencze, Gyurkovics, Ashburner, Ish-Horowicz, and Holden, 1979, Genetics 93: 917-34. allele origin discoverer synonym ref ( comments __________________________________________________________________ l(3)87Ca1 EMS l(3)SzA1 1 l(3)87Ca2 EMS l(3)SzA2 1 L l(3)87Ca3 EMS l(3)SzA3 1 semilethal l(3)87Ca4 EMS l(3)SzA4 1 l(3)87Ca5 EMS l(3)SzA5 1 E-L l(3)87Ca6 EMS l(3)SzA6 1 l(3)87Ca7 EMS l(3)SzA7 1 E l(3)87Ca8 EMS l(3)SzA8 1 l(3)87Ca9 EMS l(3)SzA9 1 l(3)87Ca10 EMS l(3)SzA10 1 semilethal l(3)87Ca11 EMS l(3)SzA11 1 l(3)87Ca12 EMS l(3)SzA12 1 l(3)87Ca13 EMS l(3)SzA13 1 l(3)87Ca14 Gelbart l(3)m107 1 l(3)87Ca15 / ray Kennison l(3)87CaE1 2 l(3)87Ca16 EMS Kennison l(3)87CaE2 2 ( 1 = Gausz, Bencze, Gyurkovics, Ashburner, Ish-Horowicz, and Holden, 1979, Genetics 93: 917-34; 2 = Kennison and Tamkun, 1988, Proc. Nat. Acad. Sci. USA 85: 8136-40. # l(3)87Cb phenotype: Hemizygotes die during prepupal stage; puparium for- mation normal, but head eversion never occurs. references: Gausz, Bencze, Gyurkovics, Ashburner, Ish-Horowicz, and Holden, 1979, Genetics 93: 917-34. allele origin discoverer synonym comments __________________________________________________________ l(3)87Cb1 EMS l(3)SzB1 l(3)87Cb2 EMS l(3)SzB2 P l(3)87Cb3 EMS l(3)SzB3 l(3)87Cb4 EMS l(3)SzB4 l(3)87Cb5 EMS l(3)SzB5 P l(3)87Cb6 EMS l(3)SzB6 l(3)87Cc1 EMS l(3)SzC1 l(3)87Cc2 EMS l(3)SzC2 L l(3)87Cc3 EMS l(3)SzC3 L l(3)87Cc4 EMS l(3)SzC4 l(3)87Cc5 EMS l(3)SzC5 l(3)87Cc6 Gelbart l(3)c4g l(3)87Cd1 EMS l(3)SzD1 l(3)87Cd2 EMS l(3)SzD2 l(3)87Cd3 EMS l(3)SzD3 l(3)87Cd4 EMS l(3)SzD4 l(3)87Cd5 EMS l(3)SzD5 l(3)87Cd6 EMS l(3)SzD6 L l(3)87Cd7 EMS l(3)SzD7 L l(3)87Cd8 EMS l(3)SzD8 L-P l(3)87Cd9 EMS l(3)SzD9 l(3)87Cd10 EMS l(3)SzD10 semilethal l(3)87Cd11 EMS l(3)SzD11 l(3)87Cd12 EMS l(3)SzD12 l(3)87Cd13 EMS l(3)SzD13 semilethal l(3)87Cd14 EMS l(3)SzD14 l(3)87Cd15 EMS l(3)SzD15 semilethal l(3)87Cd16 Gelbart l(3)m114 # l(3)87D genetic cytological locus location location included in excluded from synonym _______________________________________________________________________ l(3)87Da 3-51.7 87D3-6 Df(3R)kar-G27 Df(3R)ry1608 l(3)S3 l(3)87Db 3-52.1 87D3-6 Df(3R)kar-G27 Df(3R)ry1608 l(3)S5 l(3)87Dc 3-{52} 87D3-6 Df(3R)kar-G27 Df(3R)ry1608 l(3)B-103 l(3)87Dd 3-{52} 87D4-9 Df(3R)ry1608 Df(3R)ry36 l(3)m14 l(3)87De 3-{52} 87D7-12 Df(3R)ry74 l(3)G9 Df(3R)kar-G47 l(3)87Df 3-{52} 87D6-13 Df(3R)ry36 Df(3R)kar-G47 l(3)S12 l(3)87Dg 3-52 87D6-13 Df(3R)ry36 Df(3R)ry506 snk l(3)87Dh 3-52.1 87D11-14 Df(3R)ry75 Df(3R)ry36 pic # l(3)87Da phenotype: Homozygous lethal. l(3)87Da2 and l(3)87Da3 both partially complement l(3)87Da1 (15% and 30% survival respec- tively) and each other (75% survival). Surviving heterozy- gotes with l(3)87Da1 exhibit variation in dorsal central bris- tle number and length, and females greatly outnumber males; sex ratio and bristle morphology normal in l(3)87Da2/ l(3)87Da3 survivors. allele origin discoverer synonym ref ( ________________________________________________________ l(3)87Da1 X ray Schalet l(1)S3 l(3)87Da2 EMS Hilliker, Clark l(1)A34-1 1, 2 l(3)87Da3 EMS Hilliker, Clark l(1)A46-1 1, 2 ( 1 = Hilliker, Clark, and Chovnick, l980, Genetics 95: 95- 110; 2 = Hilliker, Clark, Gelbart, and Chovnick, l981, DIS 56: 65-72. # l(3)87Db-Dd allele origin discoverer synonym ref ( _________________________________________________________ l(3)87Db1 X ray Schalet l(3)S5 l(3)87Db2 X ray Chovnick l(3)C8a 1, 2 l(3)87Db3 X ray Chovnick l(3)E4a 1, 2 l(3)87Db4 EMS Gelbart l(3)G12 1, 2 l(3)87Db5 EMS Hilliker, Clark l(3)9-13 1, 2 l(3)87Dc1 EMS Hilliker, Clark l(3)A6-1 1, 2 l(3)87Dc2 EMS Hilliker, Clark l(3)B103 1, 2 l(3)87Dd1 EMS Deland l(3)m14 1, 2 l(3)87Dd2 EMS Hilliker, Clark l(3)10-194 1, 2 ( 1 = Hilliker, Clark, and Chovnick, l980, Genetics 95: 95- 110; 2 = Hilliker, Clark, Gelbart, and Chovnick, l981, DIS 56: 65-72. # l(3)87De phenotype: Escapers resemble MesB, but without the abdomen effect. Interacts with MesB in trans heterozygotes (Skinner, Cole, and Chovnick). allele origin discoverer synonym ref ( comments _______________________________________________________________________ l(3)87De1 EMS Hilliker, Clark l(3)2-228 1, 2 l(3)87De2 EMS Hilliker, Clark l(3)6-120 1, 2 l(3)87De3 EMS Hilliker, Clark l(3)11-147 1, 2 l(3)87De4 EMS Hilliker, Clark l(3)A39-2 1, 2 l(3)87De5 EMS Hilliker, Clark l(3)B10-1 1, 2 l(3)87De6 EMS Hilliker, Clark l(3)B13-2 1, 2 l(3)87De7 EMS Hilliker, Clark l(3)B13-3 1, 2 l(3)87De8 EMS Hilliker, Clark l(3)B23-1 1, 2 l(3)87De9 EMS Hilliker, Clark l(3)B25-1 1, 2 l(3)87De10 EMS Gelbart l(3)G9 1, 2 l(3)87De11 EMS Gelbart l(3)G15 1, 2 l(3)87De12 EMS Gelbart l(3)G21 1, 2 l(3)87De13 EMS Hilliker, Clark l(3)H2 1, 2 l(3)87De14 EMS Hilliker, Clark l(3)H23 1, 2 semilethal l(3)87De15 EMS Hilliker, Clark l(3)H37 1, 2 l(3)87De16 EMS Hilliker, Clark l(3)H73 1, 2 ( 1 = Hilliker, Clark, and Chovnick, l980, Genetics 95: 95- 110; 2 = Hilliker, Clark, Gelbart, and Chovnick, l981, DIS 56: 65-72. # l(3)87Df (A. Chovnick) location: Maps immediately to the left of, and is contiguous with ry DNA. references: Chovnick, Gelbart, McCarron, Osmond, Candido, and Baillie, 1976, Genetics 84: 233 55. Hilliker, Clark, Chovnick, and Gelbart, 1980, Genetics 95: 95-110. Hilliker, Clark, Gelbart, and Chovnick, 1981, DIS 56: 65-72. Clark and Chovnick, 1986, Genetics 114: 819-40. Dutton and Chovnick, 1990, submitted. phenotype: l(3)87Df1 and l(3)87Df2 hemizygotes completely lethal. l(3)87Df3 cold-sensitive, conditional lethal. Sur- viving cold-sensitive mutants, and underexpression variants generated by P-element transformation, display a phenotypic syndrome that can include delayed development, abnormal bris- tle morphology and female sterility. Using these phenotypes, defects in "early" and "late" l(3)87Df1 expression can be identified. l(3)87Df1 function is required in embryos, early larvae, late pupae, and during oogenesis phenocritical periods, which coincide with peaks of l(3)87Df1 transcript accumulation. Phenotypic and molecular analyses suggest that the l(3)87Df1 gene probably encodes a ribosomal protein. Genetic and molecular mapping place l(3)87Df1 immediately to the left of the rosy locus. allele origin discoverer synonym ref ( ________________________________________________________ l(3)87Df1 X ray Schalet l(3)S12 1 l(3)87Df2 EMS Hilliker, Clark l(3)B21-4 2, 3 l(3)87Df3 EMS Gelbart l(3)G1 2, 3 ( 1 = Chovnick, Gelbart, McCarron, Osmond, Candido, and Bail- lie, 1976, Genetics 84: 233-55; 2 = Hilliker, Clark, and Chovnick, l980, Genetics 95: 95-110; 3 = Hilliker, Clark, Gelbart, and Chovnick, l981, DIS 56: 65-72. # l(3)87E genetic cytological locus location location included in excluded from synonym ______________________________________________________________________________ l(3)87Ea 3-52.2 87D14-E2 Df(3R)ry75 l(3)S8, sim, schm Df(3R)l26c l(3)87Eb 3-{53} 87E1-2 Df(3R)ry1608 l(3)B16 Df(3R)l26c l(3)87Ec 3-{53} 87E1-2 Df(3R)ry1301 Df(3R)ry1608 l(3)C9a l(3)87Ed 3-52.2 87E1-4 Df(3R)ry1607 Df(3R)ry1301 Ace l(3)87Ee 3-{53} 87E2-6 Df(3R)Ace-HD1 Df(3R)ry1607 l(3)G7 l(3)87Ef 3-{53} 87E5 Df(3R)l26d Df(3R)Ace-HD1 l(3)m32 l(3)87Eg 3-{53} 87E5-12 Df(3R)lC4a l(3)m17 l(3)87Eh 3-{53} 87E5-12 Df(3R)lC4a l(3)m116 l(3)87Ei 3-{53} 87E5-12 Df(3R)lC4a l(3)S9 l(3)87Ej 3-{53} 87E5-12 Df(3R)lC4a l(3)G5 l(3)87Ek 3-{53} 87E11-F1 Df(3R)ry619 Df(3R)lC4a l(3)m112 l(3)87El 3-{53} 87E4-6 Df(3R)N78 Df(3R)ry1607 Su(var)3-7 # l(3)87Eb phenotype: Lethal in all homoallelic and heteroallelic combina- tions except two: l(3)87Eb8 shows 4% and 15% survival in com- bination with l(3)87Eb2 and l(3)87Eb5, respectively; pheno- types normal. l(3)87Eb6 allelism inferred from deficiency mapping; allele lost before others recovered. allele origin discoverer synonym ref ( _________________________________________________________ l(3)87Eb1 EMS Hilliker, Clark l(3)B16-1 1, 2 l(3)87Eb2 EMS Hilliker, Clark l(3)B16-4 1, 2 l(3)87Eb3 EMS Hilliker, Clark l(3)B27-2 1, 2 l(3)87Eb4 EMS Hilliker, Clark l(3)H13 1, 2 l(3)87Eb5 EMS Hilliker, Clark l(3)H69 1, 2 *l(3)87Eb6 X ray Schalet l(3)S6 3 ( 1 = Hilliker, Clark, and Chovnick, l980, Genetics 95: 95- 110; 2 = Hilliker, Clark, Gelbart, and Chovnick, l981, DIS 56: 65-72; 3 = Schalet, Kernaghan, and Chovnick, l964, Genetics 50: 1261-68. # l(3)87Ec-Ef references: Hilliker, Clark, and Chovnick, l980, Genetics 95: 95-110. Hilliker, Clark, Gelbart, and Chovnick, l981, DIS 56: 65-72. phenotype: All alleles lethal in the hemizygous condition. alleles: Limited complementation: l(3)87Ec1/ l(3)87Ec2, l(3)87Ec1/ l(3)87Ec3, and l(3)87Ec2/ l(3)87Ec3 give 2%, 8%, and 14% survival, respectively. Surviving progeny somewhat reduced in size relative to wild type. allele origin discoverer synonym ________________________________________________ l(3)87Ec1 EMS Hilliker, Clark l(3)B2-6 l(3)87Ec2 EMS Hilliker, Clark l(3)B26-2 l(3)87Ec3 X ray Chovnick l(3)C9a allele origin discoverer synonym ref ( ________________________________________________________ l(3)87Ee1 EMS Hilliker, Clark l(3)B1-3 1, 2 l(3)87Ee2 EMS Hilliker, Clark l(3)B9-1 1, 2 l(3)87Ee3 EMS Hilliker, Clark l(3)B13-1 1, 2 l(3)87Ee4 EMS Hilliker, Clark l(3)B30-2 1, 2 l(3)87Ee5 EMS Gelbart l(3)G7 1, 2 l(3)87Ee6 / ray Hilliker, Clark l(3)H20 1, 2 l(3)87Ee7 EMS Hilliker, Clark l(3)H34 1, 2 l(3)87Ee8 EMS Hilliker, Clark l(3)H75 1, 2 l(3)87Ee9 EMS Hilliker, Clark l(3)H91 1, 2 l(3)87Ef1 EMS Deland l(3)m32 1, 2 l(3)87Ef2 EMS J. Hall l(3)J38 1, 2 ( 1 = Hilliker, Clark, and Chovnick, l980, Genetics 95: 95- 110; 2 = Hilliker, Clark, Gelbart, and Chovnick, l981, DIS 56: 65-72. # l(3)87Eg references: Hilliker, Clark, and Chovnick, l980, Genetics 95: 95-110. Hilliker, Clark, Gelbart, and Chovnick, l981, DIS 56: 65-72. alleles: Two complementation groups; l(3)87Eg1 is the single member of one; l(3)87Eg2, l(3)87Eg4, and l(3)87Eg6 are members of the other; remaining alleles noncomplementing except for weak viability seen in l(3)87Eg5/ l(3)87Eg6 heterozygotes. allele origin discoverer synonym ref ( comments ___________________________________________________________________________ l(3)87Eg1 EMS Hilliker, Clark l(3)B1-1 1 l(3)87Eg2 EMS Hilliker, Clark l(3)B11-1 1 l(3)87Eg3 EMS Hilliker, Clark l(3)B16-3 1 l(3)87Eg4 EMS Hilliker, Clark l(3)B26-3 1 l(3)87Eg5 EMS Hilliker, Clark l(3)H45 1 l(3)87Eg6 EMS Hilliker, Clark l(3)H77 1 l(3)87Eg7 EMS Deland l(3)m17 1 l(3)87Eg8 EMS Hilliker, Clark l(3)B9-2 2 formally placed in l(3)87Ek l(3)87Eh1 EMS Deland l(3)m116 1 ( 1 = Hilliker, Clark, Gelbart, and Chovnick, 1981, DIS 56: 65-72; 2 = Manseau, Ganetzky, and Craig, 1988, Genetics 119: 407-20. # l(3)87Ei alleles: l(3)87Ei6 complements l(3)87Ei2, l(3)87Ei3, l(3)87Ei5, l(3)87Ei10, l(3)87Ei14, and l(3)87Ei15; partially complements l(3)87Ei4, l(3)87Ei7, and l(3)87Ei8 (14%, 13%, and 22% rela- tive viability, respectively); the remaining allelic combina- tions fail to complement. allele origin discoverer synonym ref ( _________________________________________________________ l(3)87Ei1 X ray Schalet l(3)S9 3 l(3)87Ei2 EMS Hilliker, Clark l(3)B1-2 1, 2 l(3)87Ei3 EMS Hilliker, Clark l(3)B1-5 1, 2 l(3)87Ei4 EMS Hilliker, Clark l(3)B2-3 1, 2 l(3)87Ei5 EMS Hilliker, Clark l(3)B8-1 1, 2 l(3)87Ei6 EMS Hilliker, Clark l(3)B8-4 1, 2 l(3)87Ei7 EMS Hilliker, Clark l(3)B12-2 1, 2 l(3)87Ei8 EMS Hilliker, Clark l(3)B15-1 1, 2 l(3)87Ei9 EMS Hilliker, Clark l(3)B21-3 1, 2 l(3)87Ei10 EMS Hilliker, Clark l(3)B26-4 1, 2 l(3)87Ei11 EMS Hilliker, Clark l(3)B28-1 1, 2 l(3)87Ei12 EMS Hilliker, Clark l(3)H9 1, 2 l(3)87Ei13 EMS Hilliker, Clark l(3)H30 1, 2 l(3)87Ei14 EMS Hilliker, Clark l(3)H32 1, 2 l(3)87Ei15 EMS Hilliker, Clark l(3)H57 1, 2 l(3)87Ei16 EMS Deland l(3)m102 1, 2 l(3)87Ej1 EMS Hilliker, Clark l(3)B4-1 1, 2 l(3)87Ej2 EMS Gelbart l(3)G5 1, 2 ( 1 = Hilliker, Clark, and Chovnick, l980, Genetics 95: 95- 110; 2 = Hilliker, Clark, Gelbart, and Chovnick, l981, DIS 56: 65-72. # l(3)87Ek references: Hilliker, Clark, and Chovnick, l980, Genetics 95: 95-110. Hilliker, Clark, Gelbart, and Chovnick, l981, DIS 56: 65-72. alleles: Three complementation groups, one with l(3)87Ek2 and l(3)87Ek4, one with l(3)87Ek1, and one with l(3)87Ek5 and l(3)87Ek6. l(3)87Ek3 fails to complement mutants in the first two but complements those in the third group. l(3)87Ek7 par- tially complements l(3)87Ek5 and l(3)87Ek6 (40% and 24% rela- tive survival, respectively) but fails to complement all other alleles; unlike other cases of complementation, these two combinations exhibit short, very thin bristles and irregularly arranged ommatidia. allele origin discoverer synonym ref ( comments _________________________________________________________________________________ l(3)87Ek2 EMS Hilliker, Clark l(3)B16-2 1 l(3)87Ek3 EMS Hilliker, Clark l(3)B17-1 1 l(3)87Ek4 EMS Hilliker, Clark l(3)H21 1 partially complements l(3)87Ek7 l(3)87Ek5 / ray Hilliker, Clark l(3)H24 1, 2 not an 87Ek allele? l(3)87Ek6 / ray Hilliker, Clark l(3)H25 1, 2 not an 87Ek allele? l(3)87Ek7 EMS Deland l(3)m112 1, 2 partially complements l(3)87Ek4 l(3)87Ek8 EMS Manseau l(3)E15 2 0.9 kb deletion l(3)87Ek9 EMS Manseau l(3)E99 2 0.9 kb deletion l(3)87Ek10 EMS Manseau l(3)E118 2 l(3)87Ek11 EMS Manseau l(3)E203 2 ( 1 = Hilliker, Clark, Gelbart, and Chovnick, l981, DIS 56: 65-72; 2 = Manseau, Ganetzky, and Craig, 1988, Genetics 119: 407-20. # DEFICIENCY MAP OF REGION 87 side breakpoint variant coordinates ( ____________________________________________________ left 87A1-2 Df(3R)kar-H5 87A1-7 l(3)87Aa 87A1-7 l(3)87A right 87A5-7 Df(3R)T63 right 87A5-7 Df(3R)T55 left 87A6-7 Df(3R)kar1W 87A6-7 Hsp70 left 87A7 Df(3R)kar-D1 87A7-9 l(3)87Ac right 87A9 Df(3R)T47 right 87A9 Df(3R)T61 87A9-B2 l(3)87Ad 87A9-B2 l(3)87Ae left 87B1 Df(3R)kar-H1 right 87B1-2 Df(3R)E229 left 87B1-2 Df(3R)kar-Sz12 left 87B1-2 Df(3R)kar-Sz15 87B1-4 l(3)87Ba left 87B2-4 Df(3R)E307 left 87B2-4 Df(3R)kar3Q 87B2-4 l(3)87Bb 87B2-4 l(3)87Bc left 87B4 Df(3R)kar-H10 left 87B3-5 Df(3R)kar-lG27 87B4-6 l(3)87Bd left 87B5-6 Df(3R)kar-H11 right 87B5-6 Df(3R)T45 87B5-9 l(3)87Be 87B5-9 l(3)87Bf 87B5-9 l(3)87Bg right 87B9 Df(3R)E079 87B9-13 l(3)87Bh 87B9-13 l(3)87Bi 87B9-13 l(3)87Bj left 87B11-13 Dr(3R)ry615 87B11-C1 l(3)87Bk 87B11-C1 l(3)87Bl 87B11-C1 l(3)87Bm left 87B15-C1 Df(3R)kar3J left 87B15-C1 Df(3R)ry1168 Hsp70 right 87C1-2 Df(3R)T41 left 87C1-3 Df(3R)ry81 left 87C2-3 Df(3R)kar3l left 87C3-4 Df(3R)kar-Sz29 87C4-5 l(3)87Ca left 87C5-6 Df(3R)kar-Sz3 right 86C5-7 Df(3R)T10 87C6 l(3)87Cb left 87C6-7 Df(3R)kar-Sz31 right 87C6-7 Df(3R)T10 right 87C6-7 Df(3R)T32 left 87C7 Df(3R)kar-Sz21 left 87C7 Df(3R)kar-Sz27 87C7 l(3)87Cc left 87C7-8 Df(3R)kar-Sz11 87C8 kar right 87C8-9 Df(3R)kar-Sz12 right 87C8-9 Df(3R)kar-Sz21 87C9 l(3)87Cd right 87C9-D1 Df(3R)kar3J right 87C9-D1 Df(3R)kar-Sz29 right 87C9-D3 Df(3R)kar-Sz31 87D1-2 Men right 87D1-2 Df(3R)E307 right 87D1-2 Df(3R)kar3Q left 87D1-2 Df(3R)ry75 left 87D2-4 Df(3R)ry614 left 87D2-4 Df(3R)ry1301 left 87D2-4 Df(3R)ry1402 left 87D3-4 Df(3R)ry1607 right 87D3-4 Df(3R)kar3l right 87D3-4 Df(3R)kar-D1 right 87D3-4 Df(3R)kar-D3 87D3-6 l(3)87Da 87D3-6 l(3)87Db 87D3-6 l(3)87Dc left 87D4-6 Df(3R)ry1608 87D4-9 l(3)87Dd left invisible Df(3R)ry36 -213 to -201 87D4-9 mes-A left Df(3R)ry74 87D4-9 mes-B left 87D7-9 Df(3R)ry619 -213 to -201 87D7-12 l(3)87De right 87D6-12 Df(3R)kar-lG27 -191 to -184 87D6-13 l(3)87Df 87D6-13 ry snk right invisible Df(3R)ry36 ~ -165 Hsc70-2 left 87D11-13 Df(3R)l26d ~ -160 87D11-14 pic right 87D11-14 Df(3R)ry614 -139 to -125 right 87D12-E1 Df(3R)kar-H1 right 87D13-14 Df(3R)kar1W right 87D14-E1 Df(3R)ry75 -139 to -125 87D14-E2 sim right 87D14-E2 Df(3R)ry81 -112 to -100 left 87E1-2 Df(3R)l26C 87E1-2 l(3)87Eb right 87D14-E1 Df(3R)kar-Sz37 right 87D14-E2 Df(3R)ry1402 -50 to -39 right 87E1-2 Df(3R)ry1608 -41 to -17 87E1-2 l(3)87Ec right 87E1-2 Df(3R)kar-Sz15 right 87E1-2 Df(3R)ry1301 +15 to +21.5 3 Ace right 87E2-3 Df(3R)ry1607 +26 to +32 left 87E3-4 Df(3R)Ace-HD1 +49 to +50.5 5 Ace left 87E4 Df(3R)GE41 +56.5 to +58.8 Su(var)3-7 +59 to +63 l(3)87Ee right 87E5-6 Df(3R)Ace-HD1 +72.5 to +77.8 right 87E5-6 Df(3R)kar-Sz11 +82 to +93 l(3)87Ef right 87E4 Df(3R)GE41 right 87E3-5 Df(3R)l26d +79.5 to +90.5 left 87E5-7 Df(3R)lC4a +73 to +85 87E5-12 l(3)87Eg 87E5-12 l(3)87Eh 87E5-12 l(3)87Ei 87E5-12 l(3)87Ej right 87E11-13 Df(3R)ry615 right 87E9-12 Df(3R)ry1168 right 87E11-F1 Df(3R)lC4a Act87E 87E11-F1 l(3)87Ek right 87E12-F1 Df(3R)ry619 right 87F1 Df(3R)kar-Sz27 right 87F11-12 Df(3R)l26c ( Molecular coordinates from Spierer, Bender, and Spierer (1983, J. Mol. Biol. 168: 35-50) and Gausz, Hall, Spierer, and Spierer, 1986, Genetics 112: 65-78). Origin 6.5 kb distal to left breakpoint of In(3R)Cbxrv1 (Bender, Spierer, and Hogness, 1983, J. Mol. Biol. 168: 17-33). # l(3)88Aa location: 3-50.3. origin: Induced by N-methyl-N'-nitro-N-nitrosoguanidine. synonym: l(3)2004. references: Shearn, Rice, Garen, and Gehring, 1971, Proc. Nat. Acad. Sci. 68: 2594-98. phenotype: Homozygous larvae die in third instar; discs reported as missing, probably rudimentary (see Szabad and Bryant, l982, Dev. Biol. 93: 240-56). Mitotic chromosomes fuzzy and swollen; 27% of cells polyploid; chromosome breaks observed (Gatti and Baker, 1989, Genes Dev. 3: 438-53). cytology: Placed in 87F12-88B1 on the basis of inclusion in Df(3R)red31 = Df(3R)87F12-14;88B2-3 but not Df(3R)red-P93 = Df(3R)88A10-B1;88C2-3. # l(3)88Ab location: 3-51.1. origin: Induced by ethyl methanesulfonate. synonym: l(3)K43. references: Shearn, Rice, Garen, and Gehring, 1971, Proc. Nat. Acad. Sci. USA 68: 2594-98. Szabad and Bryant, l982, Dev. Biol. 93: 240-56. phenotype: Homozygous larvae contain rudimentary imaginal discs, but disc primordia do not grow during larval develop- ment; testes and ovaries smaller than normal, and cell number in central nervous system reduced. Mutant gonads do not sur- vive metamorphosis when implanted into wild-type larvae. Homozygous cuticular clones appear to develop normally, but abdominal clones reduced in frequency and size compared to control clones. Mutant larvae support growth of implanted wild-type discs. Normal gene product postulated to be required for cell proliferation; survival of somatic epidermal clones attributed to perdurance. Larval ganglia exhibit extremely low mitotic index; chromosomes irregularly condensed and chro- mosome breakage observed (Gatti and Baker, 1989, Genes Dev. 3: 438-53); salivary chromosomes appear normal. alleles: allele origin discoverer synonym comments __________________________________________________________________ l(3)88Ab1 EMS l(3)K43 l(3)88Ab2 EMS Nusslein-Volhard fs(3)293-19 hypomorph; viable ( l(3)88Ab3 / ray Spradling lab l(3)88Ab4 / ray Spradling lab l(3)88Ab5 / ray Spradling lab l(3)88Ab6 / ray Spradling lab l(3)88Ab7 EMS Mortin ZM43 l(3)88Ab8 EMS Mortin ZM47 ( More detailed description below. cytology: Placed in 88A12-B1 on the basis of its inclusion in Df(3R)red-P52 = Df(3R)88A12-B1;88B4-5 but not Df(3R)red-P93 = Df(3R)88A10-B1;88C2-3. molecular biology: Region of gene contained in a 400 kb cosmid walk; position narrowed to 50 kb between the proximal break- point of Df(3R)red-P52 and the distal breakpoint of an over- lapping more proximal inversion Df(3R)293 = Df(3R)87E;88A. # l(3)88Ab2 phenotype: Homozygous females weakly fertile; produce eggs with grossly defective chorions; thin, missing most appendages and permeable. All chorion proteins reduced in abundance; chorion gene amplification reduced to 10% wild-type level (Snyder, Galanopoulos, and Kafatos, l986, Proc. Nat. Acad. Sci. USA 83: 3341-45). Heterozygotes with lethal alleles more extreme and sterile. # l(3)89A-B Based on fine structure deficiency mapping of Hughes, Nel- son, Yanuk, and Szauter (unpublished). The region of overlap between this study and that of Tiong, Bone, and Whittle in regions 89B-E have not been reconciled; they are treated separately here. genetic cytological locus location location included in excluded from synonym ________________________________________________________________ l(3)89Aa 3-{58} 89A2-5 Df(3R)c3G2 l(3)89B1 3-58 89A11-B4 Df(3R)sbd105 Df(3R)Po4 mor Df(3R)sbd45 l(3)89B2 3-58 89A11-B4 Df(3R)sbd105 Df(3R)Po4 srp Df(3R)sbd45 l(3)89B3 3-58.1 89B4-10 Df(3R)sbd45 Df(3R)sbd26 pnr # l(3)89Aa cytology: Identified as a lethal found in some, and perhaps all, TM3 balancer chromosomes based on the lethality of two different TM3 chromosomes in combination with deficiencies for the region including Df(3R)c3G2 = Df(3R)89A2-3;89A4-5. # l(3)89B-E Results of deficiency and complementation analysis of 62 lethal and eight visible mutations that fail to complement Df(3R)bxd100 = Df(3R)89B5-6;89E2-3 plus 35 lethals and ten viable mutations that fail to complement Df(3R)P15 = Df(3R)D9-E1;89E7-8 (Tiong, Bone, and Whittle, 1985, Mol. Gen. Genet. 200: 335-42) and 39 mutations that fail to complement Df(3R)P115 = Df(3R)D9-E1;89E4-5 [Sanchez-Herrero, Vernos, Marco, and Morata, 1985, Nature (London) 313: 108-13]. genetic cytological locus location location included in excluded from synonym __________________________________________________________________ l(3)89Ba 3-{58} 89B5-8 Df(3R)bxd100 Df(3R)P115 l(3)89Bb 3-{58} 89B7-C2 Df(3R)P115 Df(3R)ss-a l(3)89Bc 3-{58} 89B7-C2 Df(3R)P115 Df(3R)ss-a l(3)89Bd 3-{58} 89B7-C2 Df(3R)ss-a Df(3R)P10 l(3)89Be 3-{58} 89B7-C2 Df(3R)ss-a Df(3R)P10 l(3)89Bf 3-{58} 89B7-C2 Df(3R)ss-a Df(3R)P10 l(3)89Bg 3-{58} 89B7-C2 Df(3R)ss-a Df(3R)P10 l(3)89Bh 3-{58} 89B7-C2 Df(3R)ss-a Df(3R)P10 l(3)89Bi 3-{58} 89B7-C2 Df(3R)ss-a Df(3R)P10 l(3)89Bj 3-{58} 89B7-C2 Df(3R)ss-a Df(3R)P10 l(3)89Bk 3-{58} 89B7-C2 Df(3R)ss-a Df(3R)P10 l(3)89Bl 3-{58} 89B7-C2 Df(3R)ss-a Df(3R)P10 l(3)89Ca 3-{58} 89C Df(3R)P10 Df(3R)sbd104 l(3)89Cb 3-{58} 89C Df(3R)P10 Df(3R)sbd104 l(3)89Cc 3-{58} 89C Df(3R)P10 Df(3R)sbd104 l(3)89Cd 3-{58} 89C Df(3R)ss-a Df(3R)sbd104 l(3)89Da 3-{59} 89D9-E2 Df(3R)P2 Df(3R)Ubx109 l(3)89Db 3-{59} 89D9-E2 Df(3R)Ubx109 Df(3R)P9 l(3)89Dc 3-{59} 89D9-E2 Df(3R)Ubx109 Df(3R)P9 l(3)89Ea 3-{59} 89E1-3 Df(3R)P9 l(3)lb Df(3R)bxd100 l(3)89Eb 3-58.8 89E1-3 Df(3R)P9 Ubx Df(3R)bxd100 l(3)89Ec 3-58.8 89E2-3 Df(3R)Ubx109 Df(3R)bxd100 abdA l(3)89Ed 3-58.8 89E2-5 Df(3R)P9 Df(3R)Ubx109 AbdB l(3)89Ee 3-{59} 89E2-5 Df(3R)P9 Df(3R)Ubx109 l(3)rB l(3)89Ef 3-{59} 89E4-8 Df(3R)P115 Df(3R)P9 l(3)89Eg 3-{59} 89E4-8 Df(3R)P115 Df(3R)P9 l(3)89Eh 3-{59} 89E4-8 Df(3R)P115 Df(3R)P9 l(3)89Ei 3-{59} 89E4-8 Df(3R)P115 Df(3R)P9 l(3)89Ej 3-59.2 89E7-F1 Df(3R)C4 Df(3R)P115 # l(3)89Ba-Dc allele origin discoverer synonym ref ( ___________________________________________ l(3)89Ba1 EMS Tiong l(3)S8 1 l(3)89Ba2 EMS Tiong l(3)S15 1 l(3)89Ba3 EMS Tiong 1 l(3)89Bb1 EMS Tiong l(3)S38 1 l(3)89Bb2 EMS Tiong l(3)S54 1 l(3)89Bc1 EMS Tiong l(3)S78 1 l(3)89Bd1 EMS Tiong l(3)S2 1 l(3)89Bd2 EMS Tiong l(3)S43 1 l(3)89Be1 EMS Tiong l(3)S9 1 l(3)89Bf1 EMS Tiong l(3)S12 1 l(3)89Bf2 EMS Tiong l(3)S26 1 l(3)89Bf3 EMS Tiong 1 l(3)89Bf4 EMS Tiong 1 l(3)89Bf5 EMS Tiong 1 l(3)89Bf6 EMS Tiong 1 l(3)89Bf7 EMS Tiong 1 l(3)89Bg1 / ray Tiong l(3)S4 1 l(3)89Bg2 EMS Tiong l(3)S36 1 l(3)89Bg3 EMS Tiong 1 l(3)89Bh1 EMS Tiong l(3)S37 1 l(3)89Bi1 EMS Tiong l(3)S74 1 l(3)89Bj1 EMS Tiong l(3)S77 1 l(3)89Bj2 EMS Tiong l(3)S81 1 l(3)89Bk1 EMS Tiong l(3)S80 1 l(3)89Bl1 EMS Tiong l(3)S87 1 l(3)89Ca1 EMS Tiong l(3)S40 1 l(3)89Ca2 EMS Tiong l(3)S89 1 l(3)89Ca3 EMS Tiong 1 l(3)89Cb1 EMS Tiong l(3)S53 1 l(3)89Cc1 EMS Tiong l(3)S73 1 l(3)89Cd1 EMS Tiong l(3)S59 1 l(3)89Cd2 EMS Tiong l(3)S88 1 l(3)89Cd3 EMS Tiong l(3)S93 1 l(3)89Da1 EMS Tiong l(3)S22 1 l(3)89Db1 EMS Tiong l(3)S10 1 l(3)89Db2 EMS Tiong l(3)S28 1 l(3)89Db3 EMS Tiong l(3)S 1 l(3)89Db4 EMS Tiong l(3)S 1 l(3)89Db5 EMS Tiong l(3)S 1 l(3)89Db6 EMS Tiong l(3)S 1 l(3)89Db7 EMS Tiong l(3)S 1 l(3)89Dc1 EMS Tiong l(3)S59 1 l(3)89Dc2 EMS Tiong l(3)S88 1 l(3)89Dc3 EMS Tiong l(3)S93 1 ( 1 = Tiong, Bone, and Whittle, 1985, Mol. Gen. Genet. 200: 335-42. # l(3)89Ea phenotype: Embryonic morphology normal. alleles: allele origin discoverer synonym ref ( ____________________________________________ l(3)89Ea1 EMS 1 l(3)89Ea2 EMS 1 l(3)89Ea3 EMS 1 l(3)89Ea4 EMS 1 l(3)89Ea5 EMS 1 l(3)89Ea6 EMS 1 l(3)89Ea7 EMS 1 l(3)89Ea8 EMS 1 l(3)89Ea9 EMS 1 l(3)89Ea10 X ray 1 l(3)89Ea11 EMS Tiong l(3)S3 2 l(3)89Ea12 EMS Tiong l(3)S27 2 l(3)89Ea13 EMS Tiong l(3)47 2 l(3)89Ea14 EMS Tiong 2 l(3)89Ea15 EMS Tiong 2 l(3)89Ea16 EMS Tiong 2 l(3)89Ea17 EMS Tiong 2 l(3)89Ea18 EMS Tiong 2 l(3)89Ea19 EMS Tiong 2 l(3)89Ea20 EMS Tiong 2 l(3)89Ea21 EMS Tiong 2 l(3)89Ea22 EMS Tiong 2 l(3)89Ea23 EMS Tiong 2 l(3)89Ea24 EMS Tiong 2 l(3)89Ea25 EMS Tiong 2 l(3)89Ea26 EMS Tiong 2 l(3)89Ea27 EMS Tiong 2 l(3)89Ea28 EMS Tiong 2 l(3)89Ea29 EMS Tiong 2 l(3)89Ea30 EMS Tiong 2 l(3)89Ea31 EMS Tiong 2 l(3)89Ea32 EMS Tiong 2 l(3)89Ea33 EMS Tiong 2 l(3)89Ea34 EMS Tiong 2 l(3)89Ea35 EMS Tiong 2 l(3)89Ea36 EMS Tiong 2 ( 1 = Sanchez-Herrero, Vernos, Marco, and Morata, 1985, Nature (London) 313: 108-13; 2 = Tiong, Bone, and Whittle, 1985, Mol. Gen. Genet. 200: 335-42. # l(3)89Ee phenotype: Hemizygous embryos normal in morphology. alleles: allele origin discoverer synonym ref ( ___________________________________________ l(3)89Ee1 EMS 1 l(3)89Ee2 EMS 1 l(3)89Ee3 X ray 1 l(3)89Ee4 EMS Tiong l(3)S56 2 l(3)89Ee5 EMS Tiong l(3)S72 2 l(3)89Ee6 EMS Tiong 2 l(3)89Ef1 EMS Tiong l(3)S68 2 l(3)89Ef2 EMS Tiong l(3)S85 2 l(3)89Eg1 EMS Tiong l(3)S79 2 l(3)89Eh1 EMS Tiong l(3)S92 2 l(3)89Eh2 EMS Tiong l(3)S64 2 l(3)89Ei1 / ray Tiong l(3)H4 2 l(3)89Ej1 EMS Ivy ( 1 = Sanchez-Herrero, Vernos, Marco, and Morata, 1985, Nature (London) 313: 108-13; 2 = Tiong, Bone, and Whittle, 1985, Mol. Gen. Genet. 200: 335-42. # l(3)89Ej orgin: Induced by ethyl methanesulfonate. references: Ivy, 1981, Ph.D. Thesis, University of California, San Diego. phenotype: Homozygotes die as embryos; cell lethal in cuticular clones. Heterozygous males display approximately 4% nondis- junction of both sex and fourth chromosomes; diplo-chromosome exceptions more frequent than nullo-chromosome exceptions. Slight evidence for autosomal nondisjunction and second- division sex-chromosome nondisjunction in males and sex- and fourth-chromosome nondisjunction in females. # DEFICIENCY MAP OF REGION 89 side breakpoint variant DNA coordinates _______________________________________________________ cv-c Tm2 left 88F7-89A1 Df(3R)Po4 Act88F left 88F9-89A1 Df(3R)sbd105 left 89A1-2 Df(3R)Po2 left 89A1-2 Df(3R)Po3 Po Aldox1 left 89A2-3 Df(3R)c3G2 c(3)G l(3)89Aa rec1 right 89A4-5 Df(3R)c3G2 right 89A11-13 Df(3R)Po2 right 89A11-13 Df(3R)Po3 right 89A11-13 Df(3R)Po4 mor srp left 89B4 Df(3R)sbd45 pnr left 89B9-10 Df(3R)sbd26 right 89B9-10 Df(3R)sbd105 sbd Sb right 89B10 Df(3R)sbd45 right 89C7-D1 Df(3R)sbd26 left 89B5-6 Df(3R)bxd100 89B5-7 l(3)89Ba left 89B7-8 Df(3R)P115 89B7-C2 l(3)Bb 89B7-C2 l(3)Bc left Df(3R)ss-a 89B7-C2 l(3)Bd 89B7-C2 l(3)Be 89B7-C2 l(3)Bf 89B7-C2 l(3)Bg 89B7-C2 l(3)Bh 89B7-C2 l(3)Bi 89B7-C2 l(3)Bj 89B7-C2 l(3)Bk 89B7-C2 l(3)Bl left 89C1-2 Df(3R)P10 89C l(3)Ca 89C l(3)Cb 89C l(3)Cc 89C ss right 89C Df(3R)sbd104 89C l(3)Cd right Df(3R)ss-a left 89D9-E1 Df(3R)P2 89D9-E1 l(3)89Da left 89D1-2 Df(3R)Ubx109 89E1 Fas1 89D9-E1 l(3)89Db 89D9-E1 l(3)89Dc left 89D9-E1 Df(3R)P9 89D9-E3 l(3)89Ea Ubx left 89E2-3 Df(3R)bxd110 -27 kb right 89E2-3 Df(3R)bxd100 -18 kb left 89E3-4 Df(3R)bxd111 -3 kb abdA right 89E1-2 Df(3R)P10 +35 to +36 kb right 89E2-3 Df(3R)P2 +78 to +81 kb left 89E3-4 Df(3R)Ubx109 +86 to +93 kb left 89E2-3 Df(3R)C4 +133.5 to +137 kb AbdB 89E4-8 l(3)89Ee right 89E4-5 Df(3R)P9 +225 to +230 kb 89E4-8 l(3)89Ef 89E4-8 l(3)89Eg 89E4-8 l(3)89Eh 89E4-8 l(3)89Ei right 89E7-8 Df(3R)P115 l(3)89Ej right 89F2-4 Df(3R)C4 right 90B Df(3R)bxd111 # l(3)91C A series of lethals that fail to complement a deficiency that includes Cha; investigated by Myers and Gelbart (unpub- lished). genetic cytological locus location location included in excluded from synonym ________________________________________________________________ l(3)91Ca 3-{65} 91C2-D1 Df(3R)Cha1 Df(3R)Cha6 l(3)CR1 l(3)91Cb 3-{65} 91C2-D1 Df(3R)Cha6 Df(3R)Cha9 l(3)CR2 l(3)91Cc 3-64.6 91C7-D8 Df(3R)Cha6 Cha Df(3R)Cha9 l(3)91Cd 3-{65} 91C7-D1 Df(3R)5 Df(3R)Cha10 l(3)CR3 allele origin synonym _____________________________ l(3)91Ca1 EMS l(3)CR1M29 l(3)91Ca2 EMS l(3)CR1M73 l(3)91Cb1 EMS l(3)CR2M19 l(3)91Cb2 EMS l(3)CR2M24 l(3)91Cb3 EMS l(3)CR2M33 l(3)91Cb4 EMS l(3)CR2M44 l(3)91Cb5 EMS l(3)CR2M76 l(3)91Cd1 EMS l(3)CR3M43 l(3)91Cd2 EMS l(3)CR3M45 l(3)91Cd3 EMS l(3)CR3M49 # DEFICIENCY MAP OF REGION 91C-92A side breakpoint variant ________________________________ left 91B3 Df(3R)Cha5 left 91C2-3 Df(3R)Cha1 l(3)91Ca left Df(3R)Cha6 l(3)91Cb left 91C7-D1 Df(3R)Cha9 91C7-D1 Cha right Df(3R)Cha6 l(3)91Cd right 91D1 Df(3R)Cha5 right 92A1 Df(3R)Cha1 right 92A2 Df(3R)Cha9 # l(3)91F-92A Two independent saturation studies carried out by groups at Koln and Bloomington, using different deficiencies for both selection and mapping of lethal mutations; the ambiguities resolved by Lehmann using complementation and deficiency map- ping to a common set of deficiencies. The order l(3)91Fa nos l(3)91Fb l(3)91Fe l(3)91Ff l(3)92Aa Dl also determined by recombination. genetic cytological locus location location included in excluded from synonym _______________________________________________________________________ l(3)91Fa 3-{65} 91F11-13 Df(3R)Dl-X43 Df(3R)Dl-A143 C2 l(3)91Fb 3-{65} 91F13 Df(3R)Dl-A143 Df(3R)Dl-HD28 C3 l(3)91Fc 3-{65} 91F13 Df(3R)Dl-A143 Df(3R)Dl-HD28 C5 l(3)91Fe 3-{65} 91F13 Df(3R)Dl-A143 Df(3R)Dl-HD28 l(3)91Ff 3-{65} 91F13-92A2 Df(3R)Dl-HD28 Df(3R)Dl-KX12 l(3)92Aa 3-{66} 92A2 Df(3R)Cha1a C4, l(3)91Fd Df(3R)Dl-KX12 l(3)92Ab 3-66.2 Dl allele origin synonym ref ( ________________________________ l(3)91Fa1 EMS BE40 1 l(3)91Fa2 EMS BE41 1 l(3)91Fa3 EMS BE42 1 l(3)91Fa4 EMS BE43 1 l(3)91Fa5 EMS BE44 1 l(3)91Fa6 EMS C2-8 2 l(3)91Fa7 EMS C2-10 2 l(3)91Fa8 EMS C2-13 2 l(3)91Fa9 EMS C2-14 2 l(3)91Fa10 EMS C2-15 2 l(3)91Fa11 EMS C2-22 2 l(3)91Fa12 EMS C2-23 2 l(3)91Fb1 EMS BE50 1 l(3)91Fb2 EMS BE51 1 l(3)91Fb3 EMS BE52 1 l(3)91Fb4 EMS C3-16 2 l(3)91Fb5 EMS C3-17 2 l(3)91Fb6 EMS C3-19 2 l(3)91Fc1 EMS BE60 1 l(3)91Fc2 EMS BE61 1 l(3)91Fc3 EMS BE62 1 l(3)91Fe1 EMS BE80 1 l(3)91Fe2 EMS BE81 1 l(3)91Fe3 EMS C4-4 2 l(3)91Fe4 EMS C4-4 2 l(3)91Fe5 EMS C4-7 2 l(3)91Fe6 EMS C4-9 2 l(3)91Fe7 EMS C4-18 2 l(3)91Ff1 EMS BE90 1 l(3)91Ff2 EMS BE91 1 l(3)92Aa1 EMS BE70 1 l(3)92Aa2 EMS BE71 1 l(3)92Aa3 EMS BE72 1 l(3)92Aa4 EMS C4-1 2 l(3)92Aa5 EMS C4-2 2 l(3)92Aa6 EMS C4-6 2 l(3)92Aa7 EMS C4-20 2 l(3)92Aa8 EMS C4-21 2 ( 1 = Alton, Fechtel, Terry, Meikle, and Muskavitch, 1988, Genetics 118: 235-45; 2 = Vassin and Campos-Ortega, 1987, Genetics 116: 433-45. # DEFICIENCY MAP OF REGION 91-92 side breakpoint variant ___________________________________ left 91F1-2 Df(3R)Dl-KX12 left 91F11 Df(3R)X43 l(3)91Fa left 91F13 Df(3R)Dl-A143 l(3)91Fb nos l(3)91Fe l(3)91Fc left 91F6-13 Df(3R)Dl-HD28 l(3)91Ff left 92A2 Df(3R)Dl-KX12 l(3)92Aa right 92A2 Df(3R)ChaM1a Dl right 92A2 Df(3R)Bxd110 right 92A2-3 Df(3R)Dl-A143 right 92A2-3 Df(3R)Dl-HD28 right 92A3-6 Df(3R)Dl-BX12 right 92A4 Df(3R)Dl-KX12 right 92A8-10 Df(3R)Dl-X43 # l(3)93 Eighteen loci that have mutated to 60 lethal alleles plus one locus inferred from the lethality of heterozygotes for a pair of overlapping deficiencies. Mutations were induced with a variety of mutagenic agents and selected on the basis of inviability in combination with either Df(3R)e-Gp4 = Df(3R)93B11-13;93D7-9 or Df(3R)e-H4 = Df(3R)93C3-6;93F6-8, and therefore are confined to the region 93B11 to 93F8. The region also contains the locus of ebony and the 93D heat-shock locus; none of the mutants affected the heat-shock gene, but the locus inferred from the inviability of heterozygotes for two overlapping deficiencies, l(3)93De, appears to be respon- sible for the heat-shock puff (Mohler and Pardue, l984, Genetics 106: 249-65). genetic cytological locus location location included in excluded from synonym _________________________________________________________________________ l(3)93Ba 3-{70} 93B11-C6 Df(3R)e-F3 Df(3R)e-F4 l(3)er7 l(3)93Bb 3-{70} 93B11-C6 Df(3R)e-F3 Df(3R)e-F4 l(3)er4 allele origin synonym comments ___________________________________________________ l(3)93Ba1 EMS l(3)er7EC3 l(3)93Ba2 EMS l(3)er7EC4 l(3)93Ba3 EMS l(3)er7EC8 l(3)93Ba4 EMS l(3)er7EC9 l(3)93Ba5 EMS l(3)er7EC10 l(3)93Ba6 EMS l(3)er7EC30 l(3)93Bb1 EMS l(3)er4EC2 l(3)93Bb2 EMS l(3)er4EC16 outspread wings l(3)93Bb3 EMS l(3)er4EC25 l(3)93Bb4 EMS l(3)er4EC27 l(3)93Bb5 EMS l(3)er4EC33 l(3)93Bb6 / ray l(3)er4GC15 l(3)93Bb7 / ray l(3)er4GC16 l(3)93Bb8 / ray l(3)er4GC17 genetic cytological locus location location included in excluded from synonym __________________________________________________________________________ l(3)93Ca 3-{70} 93C3-6 Df(3R)e-F4 Df(3R)e-D7 l(3)er6 l(3)93Cb 3-{70} 93C3-6 Df(3R)e-D7 Df(3R)e-H4 l(3)er5 l(3)93Cc 3-70.5 93C3-D4 Df(3R)e-H4 Df(3R)e-R1 l(3)er14 l(3)93Cd 3-{70} 93C3-D4 Df(3R)e-H4 l(3)er2 allele origin synonym comments __________________________________________________________ l(3)93Ca1 EMS l(3)er6EC7 l(3)93Ca2 EMS l(3)er6EC11 l(3)93Ca3 / ray l(3)er6GC20 l(3)93Cb1 EMS l(3)er5EC1 l(3)93Cb2 EMS l(3)er5EC18 l(3)93Cb3 EMS l(3)er5EC26 l(3)93Cb4 / ray l(3)er5GC18 In(3R)81F;93C l(3)93Cb5 / ray l(3)er5GC19 l(3)93Cb6 / ray l(3)er5GC21 In(3R)91A;93C l(3)93Cc1 DEB l(3)er14DC1 l(3)93Cd1 EMS l(3)er2EC21 l(3)93Cd2 EMS l(3)er2EC24 temperature sensitive l(3)93Cd3 / ray l(3)er2GC11 genetic cytological locus location location included in excluded from synonym ___________________________________________________________________ Df(3R)e-R1 l(3)93Da 3-{70} 93D2-6 Df(3R)e-H5 Df(3R)e-R1 l(3)er1 l(3)93Db 3-{70} 93D4-9 Df(3R)e-Gp4 Df(3R)e-H5 l(3)er8 l(3)93Dc 3-{70} 93D4-9 Df(3R)e-Gp4 Df(3R)e-H5 l(3)er11 l(3)93Dd 3-{70} 93D4-9 Df(3R)e-Gp4 Df(3R)e-H5 l(3)er9 l(3)93De 3-{70} 93D4-9 Df(3R)e-Gp4 l(3)er3 Df(3R)e-GC14 l(3)93Df 3-{70} 93D7-10 Df(3R)e-F2 Df(3R)e-Gp4 l(3)er19 l(3)93Dg 3-{70} 93D7-10 Df(3R)e-F2 Df(3R)e-Gp4 l(3)er13 l(3)93Dh 3-{70} 93D7-10 Df(3R)e-F2 Df(3R)e-Gp4 l(3)er16 l(3)93Di 3-{70} 93D7-10 Df(3R)e-F1 Df(3R)e-GC9 l(3)er12 l(3)93Dj 3-{70} 93D7-E8 Df(3R)e-F3 Df(3R)e-F1 l(3)er10 allele origin synonym comments ____________________________________________________________ l(3)93Da1 EMS l(3)er1EC19 10% survival l(3)93Da2 EMS l(3)er1EC20 l(3)93Da3 DEB l(3)er1DC3 l(3)93Da4 / ray l(3)er1GC8 l(3)93Da5 / ray l(3)er1GC31 l(3)93Db1 EMS l(3)er8EC13 l(3)93Db2 EMS l(3)er8EC17 l(3)93Db3 EMS l(3)er8EC28 l(3)93Db4 EMS l(3)er8EC32 M-like with In(3)GC25 l(3)93Db5 EMS l(3)er8EC37 l(3)93Dc1 EMS l(3)er11EC36 l(3)93Dc2 EMS l(3)er11EC38 warped opaque wings l(3)93Dd1 EMS l(3)er9EC15 viable with l(3)93Dd2 l(3)93Dd2 / ray l(3)er9GC23 In(3)81F;93D; viable with roughened eyes l(3)93De Hsr93D inferred from l(3)er3 deficiency analysis l(3)93Df1 / ray l(3)er19GC30 warped wings; cannot stand or walk; die soon l(3)93Dg1 EMS l(3)er13EC40 l(3)93Dg2 EMS l(3)er13EC43 l(3)93Dh1 EMS l(3)er16EC44 l(3)93Dh2 / ray l(3)er16GC27 # l(3R)93Di All alleles semilethal; survival of different alleles over deficiency varies. allele origin synonym comments __________________________________________________ l(3)93Di1 EMS l(3)er12EC35 l(3)93Di2 EMS l(3)er12EC39 l(3)93Di3 / ray l(3)er12GC32 l(3)93Dj1 EMS l(3)er10EC34 l(3)93Dj2 EMS l(3)er10EC42 l(3)93Dj3 / ray l(3)er10GC24 l(3)93Dj4 / ray l(3)er10GC25 In(3R)93E;94A l(3)93Dj5 / ray l(3)er10GC29 l(3)93Dj6 / ray l(3)er10GC33 genetic cytological locus location location included in excluded from synonym __________________________________________________________________________ l(3)93Fa 3-{73} 93E6-F8 Df(3R)e-D7 Df(3R)e-F3 l(3)er17 l(3)93Fb 3-{73} 93F6-8 Df(3R)e-H4 Df(3R)e-D7 l(3)er15 l(3)93Fc 3-{73} 93F6-8 Df(3R)e-F2 Df(3R)e-Gp4 l(3)er18 allele origin synonym comments ___________________________________________________ l(3)93Fa1 / ray l(3)er17GC28 l(3)93Fa2 DEB l(3)er17DC4 l(3)93Fb1 DEB l(3)er15DC2 l(3)93Fc1 EMS l(3)er18EC29 warped wings; female sterile l(3)93Fc2 / ray l(3)er18GC26 5% survival # DEFICIENCY MAP OF REGION 93B-F side breakpoint variant _____________________________________ left 93A6-B1 Df(3R)e-F2 left 93B3-5 Df(3R)-R1 left 93B8-13 Df(3R)e-F1 left 93B8-13 Df(3R)e-F3 left 93B11-13 Df(3R)e-GC9 left 93B11-13 Df(3R)e-Gp4 left 93B11-13 Df(3R)e-H5 93B11-C6 l(3)93Ba 93B11-C6 l(3)93Bb left 93C3-6 Df(3R)e-F4 93C3-6 l(3)93Ca left 93C In(3R)GC18LGC23R left 93C3-6 Df(3R)e-D7 left 93C3-6 Df(3R)e-GC3 left 93C3-6 Df(3R)e-H6 right 93D7-10 Df(3R)e-F1 93C3-6 l(3)93Cb left 93C3-6 Df(3R)e-H4 93C3-D4 l(3)93Cc 93C3-D4 l(3)93Cd 93D2-6 e right 93D2-4 Df(3R)e-R1 93D2-6 l(3)93Da right 93D4-6 Df(3R)e-H5 93D4-9 l(3)93Db 93D4-9 l(3)93Dc 93D4-9 l(3)93Dd left invisible Df(3R)GC14 right 93D In(3R)GC18LGC23R 93D4-9 Hsr93D ( right 93D7-9 Df(3R)e-Gp4 93D7-10 l(3)93Df 93D7-10 l(3)93Dg 93D7-10 l(3)93Dh right invisible Df(3R)GC14 right 93D7-10 Df(3R)e-F2 right 93D9-10 Df(3R)e-GC9 93D9-10 l(3)93Di right 93D7-10 Df(3R)e-F1 93D7-E8 l(3)93Dj right 93E6-11 Dr(3R)e-F3 93E6-F8 l(3)93Fa right 93F6-8 Df(3R)e-D7 93F6-8 l(3)93Fb 93F6-8 l(3)93Fc right 93F6-8 Df(3R)e-H4 right 94F11-14 Dr(3R)e-GC3 right 94A Dr(3R)e-F4 right 94A Dr(3R)e-H6 ( Inferred from the lethality of Df(3R)e-Gp4/Df(3R)GC14; no mutant alleles recovered. # l(3)96F Four complementation groups encountered in a screen for lethal mutations not complemented by Df(3R)Espl4 = Df(3R)96F8-9;96F12-13 (Ziemer, Tietze, Knust, and Campos- Ortega, 1988, Genetics 119: 63-74). genetic cytological locus location location included in synonym ___________________________________________________ l(3)96Fa 3-{90} 96F8-13 Df(3R)Espl4 l(3)C1 l(3)96Fb 3-{90} 96F8-13 Df(3R)Espl4 l(3)C2 l(3)96Fc 3-{90} 96F8-13 Df(3R)Espl4 l(3)C3 l(3)96Fd 3-{90} 96F8-13 Df(3R)Espl4 E(spl) allele origin synonym __________________________ l(3)96Fa1 EMS l(3)B103 l(3)96Fb1 EMS l(3)A3 l(3)96Fb2 EMS l(3)B17 l(3)96Fc1 EMS l(3)B105 # l(3)99D-E Eleven lethal and one dominant flightless complementation group identified among 29 mutations uncovered by Df(3R)ca124 = Df(3R)99A2-3;99E4-5 but distal to the breakpoint of T(Y;3)B81 = T(Y;3)YL;99D3 (Warmke, Kreuz, and Falkenthal, 1989, Genetics 122: 139-51). genetic cytological locus location location included in ( excluded from ( _____________________________________________________________ l(3)99Da 3-101 99D3-9 Dp(3;1)R10 l(3)99Db 3-101 99D3-9 Dp(3;1)R10 l(3)99Dc 3-101 99D3-9 Dp(3;1)R10 l(3)99Dd 3-101 99D3-9 Dp(3;1)R10 l(3)99De 3-101 99D3-9 Dp(3;1)R10 l(3)99Df 3-101 99D3-9 Dp(3;1)R10 l(3)99Dg 3-101 99D3-9 Dp(3;1)R10 l(3)99Dh 3-101 99D3-9 Dp(3;1)R10 l(3)99Di 3-101 99D3-9 Dp(3;1)R10 Dp(3;1)67A l(3)99Dj 3-101 99D3-9 Dp(3;1)R10 Dp(3;1)67A l(3)99Ea 3-101 99D9-E3 Dp(3;1)67A Dp(3;1)124P ( Deficiency mapping based on the terminal deficiency, 3PYDB81, which is broken in 99D3, partially covered by ter- minal duplications of varying lengths. allele origin synonym __________________________ l(3)99Da1 EMS l(3)S5 l(3)99Db1 EMS l(3)J2 l(3)99Db2 EMS l(3)SF1 l(3)99Db3 EMS l(3)S l(3)99Dc1 EMS l(3)L1 l(3)99Dc2 EMS l(3)SF5 l(3)99Dd1 EMS l(3)J4 l(3)99Dd2 EMS l(3)SF6 l(3)99De1 EMS l(3)J6 l(3)99Df1 EMS l(3)E38 l(3)99Dg1 EMS l(3)L6 l(3)99Dg2 EMS l(3)L7 l(3)99Dg3 EMS l(3)SF3 l(3)99Dg4 EMS l(3)SF8 l(3)99Dh1 EMS l(3)L5 l(3)99Di1 EMS l(3)J5 l(3)99Di2 EMS l(3)L4 l(3)99Di3 EMS l(3)SF4 l(3)99Di4 EMS l(3)SF7 l(3)99Di5 EMS l(3)SF9 l(3)99Dj1 EMS l(3)J7 l(3)99Dj2 EMS l(3)L3 l(3)99Dj3 EMS l(3)L7 l(3)99Dj4 EMS l(3)S1 l(3)99Dj5 EMS l(3)S3 l(3)99Ea1 EMS l(3)J1 l(3)99Ea2 EMS l(3)J3 l(3)99Ea3 EMS l(3)L9 l(3)99Ea4 EMS l(3)S4 # DEFICIENCY MAP OF REGION 99D-E side breakpoint variant __________________________________ 99D3 T(Y;3)B81 l(3)99Da l(3)99Db l(3)99Dc l(3)99Dd l(3)99De l(3)99Df l(3)99Dg l(3)99Dh right 99D6-9 Dp(3;1)ca-R10 l(3)99Di l(3)99Dj right 99D9-E1 Dp(3;1)ca67A l(3)99Ea Mlc2 right 99E2-3 Dp(3;1)ca124P # l(3)109 location: 3-36.5. origin: Induced by ethyl methanesulfonate. references: Ferrus and Kankel, 1981, Dev. Biol. 85: 485-504. phenotype: Homozygous lethal; cell viable; homozygous cells 2-3 times normal size. # l(3)1215 location: 3-50.6. origin: Induced by ethyl methanesulfonate. discoverer: Shearn. references: Bryant, Girton, and Martin, 1980, Insect Biology in the Future (M. Locke and D.S. Smith, eds.). Academic Press, New York, pp. 517-42 (fig.). Held, Duarte, and Derakhshanian, 1986, Wihelm Roux's Arch. Dev. Biol. 195: 145-57. phenotype: Homozygotes die as pharate adults. Discs giving rise to segmented appendages develop abnormally; legs much shorter than normal; normal numbers of foreshortened segments with reduced numbers of bristles. Tibias of all legs show mirror-image duplication of distal elements with inverted polarity with indications of incipient joint development at the plane of symmetry; other segments not so affected although some pattern deficiencies and bristles with reversed polarity are observed. Tarsi unsegmented. Antennal joints either abnormal or absent; second segment with reduced number of bristles. # l(3)a location: 3-81.6. origin: Spontaneous in In(3R)C. discoverer: Morgan, 11l. synonym: l(3)1. references: Muller, 1918, Genetics 3: 422-99. phenotype: Lethal homozygous. Reduced recovery of M(3)95A- bearing daughters from In(3R)C, l(3)a/M(3)95A females (Schultz). RK3. other information: Results of Bridges interpreted to show allelism to M(3)95A3 (3-79.7); may have been related to mater- nal effect described by Schultz. Position based on crosses by Muller (1918), in which he used l(3)a separated from In(3R)C. # l(3)ac: lethal (3) accessory location: 3- (midregion). discoverer: Schultz, 25g. phenotype: Enhances maternal effect of In(3R)C, l(3)a on recovery of M(3)95A daughters from M(3)95A/In(3R)C, l(3)a mothers (Schultz). RK3. # l(3)AFA location: 3-72 [l(3)AFA7]. origin: Induced by ethyl methanesulfonate in In(3R)AFA. references: Caggese, Caizzi, Morea, Scalenghe, and Ritossa, 1979, Proc. Nat. Acad. Sci. USA 76: 2385-89. cytology: Placed in 93C3-E2 based on inclusion in Df(3R)e-D7 and Df(3R)e-F1. other information: Two lethals l(3)AFA7 and l(3)AFA17; allelism not ascertained; also not tested against l(3)93 lethals of Mohler and Pardue. # l(3)AM1 origin: Induced by ethyl methanesulfonate. references: Seecof, 1977, Am. Zool. 17: 577. phenotype: Nearly dominant lethal; only 4% of l/l plus l/+ genotypes survive. Defective in myogenesis; embryo homogen- ates in culture display normal axon growth but reduced nucleus; axon ratio suggests myogenesis reduced. #*l(3)blo-l: lethal (3) bloated larvae location: 3- (to the left of p). discoverer: Bridges, 25k7. references: Chen, 1929, J. Morphol. 47: 135-99. phenotype: Larvae become very large and transparent, die in the prepupal stage. Growth of imaginal disks irregular. RK2. # l(3)bt: lethal (3) brain tumor references: Gateff, 1981, 7th European Drosophila Research Conference Abstracts, p. 42. phenotype: Heat sensitive; at 29 third-instar larvae develop brain tumors and die either before or after pupation. Optic neuroblasts and their derivatives, the ganglion mother cells, proliferate. Brain enlarged and malformed; grow in malignant fashion when transplanted into normal hosts. TSP 0-12 hours of embryonic life. # l(3)ds: lethal (3) discs small A series of late-larval, early-pupal lethals characterized by having small imaginal discs; isolated by Shearn and Garren (1974, Proc. Nat. Acad. Sci. USA 71: 1393-97). Originally designated l(3)B, but renamed ds to conform to the terminology for the same types of mutants recovered on the X chromosome. genetic can can support locus location origin synonym differentiate ( differentiation | _____________________________________________________________________ l(3)ds1 68.0 EMS l(3)B1 no l(3)ds21 42.8 EMS l(3)B2 l(3)ds22 EMS l(3)B7 l(3)ds3 81.4 EMS l(3)B3 l(3)ds4 50.9 EMS l(3)B4 l(3)ds5 47.0 EMS l(3)B5 yes no l(3)ds6 49.3 EMS l(3)B6 l(3)ds8 53.6 NG l(3)B8 l(3)ds9 50.8 NG l(3)B9 l(3)ds10 35.7 NG l(3)B10 l(3)ds11 19.6 NG l(3)B11 l(3)ds12 30.9 NG l(3)B12 l(3)ds13 74.0 NG l(3)B13 l(3)ds14 48.7 ICR l(3)B14 l(3)ds151 81.7 ICR l(3)B15 yes l(3)ds152 / l(3)A11 l(3)ds16 49.0 ICR l(3)B16 l(3)ds17 44.1 ICR l(3)B17 ( Test of the ability of suspensions of embryonic cells tran- splanted first into adult hosts for proliferation and then into larval hosts for metamorphosis to differentiate into adult cuticular structures. | Test of ability of mutant larvae to act as hosts for the differentiation of wild-type imaginal discs. Wild-type discs transplanted into l(3)ds5 hosts, but not into l(3)ds1 hosts, can grow and differentiate when subsequently transplanted back into wild-type third-instar larvae. / Discless. # l(3)dsl: lethal (3) discless A series of late-larval, early-pupal lethals characterized by the absence of imaginal discs; isolated by Shearn and Gar- ren (1974, Proc. Nat. Acad. Sci. USA 71: 1393-97). Origi- nally designated l(3)A, but renamed dsl to conform to the ter- minology for the same types of mutants recovered on the X chromosome. genetic can can support locus location origin synonym differentiate ( differentiation | ___________________________________________________________________ l(3)dsl1 3-25.9 EMS l(3)A1 l(3)dsl2 3-82.7 EMS l(3)A2 l(3)dsl3 3-50.3 EMS l(3)A3 no l(3)dsl4 3-0.0 EMS l(3)A4 l(3)dsl5 3-51.1 EMS l(3)A5 no yes l(3)dsl6 3-50.3 NG l(3)A6 l(3)dsl7 3-70.4 ICR170 l(3)A7 l(3)dsl8 3-29.7 ICR170 l(3)A8 l(3)dsl9 3-74.3 ICR170 l(3)A9 l(3)dsl10 3- l(3)A10 no yes ( Test of the ability of suspensions of embryonic cells tran- splanted first into adult hosts for proliferation and then into larval hosts for metamorphosis to differentiate into adult cuticular structures. | Test of ability of mutant larvae to act as hosts for the differentiation of wild-type imaginal discs. # l(3)DTS: lethal (3) Dominant Temperature Sensitive A group of ten ethyl-methanesulfonate-induced dominant- temperature-sensitive mutations on the third chromosome; heterozygotes are lethal when raised at 29, but survive rear- ing at 22. Only l(3)DTS2 viable as homozygote at 22 (Holden and Suzuki, 1973, Genetics 73: 445-58). Only l(3)DTS4 expressed dominant lethality in one dose in triploids. genetic locus location phenotype lethal phase at 29 _______________________________________________________________ l(3)DTS1 3-78 Minute-like at 22 LP-A l(3)DTS2 3-33.4 EP l(3)DTS3 ( 3-84.5 L3 l(3)DTS4 3-24.5 E-L1 l(3)DTS5 | 3-44.3 P(hfw-like) l(3)DTS6 st-pp Minute-like at 22 P l(3)DTS7 3-42.3 P *l(3)DTS8 3-55.5 *l(3)DTS9 dominant female sterile *l(3)DTS10 dominant female sterile ( More detailed description follows. | See l(3)73Ai. # l(3)DTS3 Heterozygous larvae raised at 29 arrested at the third lar- val instar for up to two weeks; exhibit grossly hypertrophied ring glands due to the growth of the prothoracic gland cells. The nuclei possess polytene chromosomes which are as large as those of salivary gland nuclei; their banding pattern is simi- lar but not identical to that of salivary gland polytene chro- mosomes, but the puffing patterns are quite different. Salivary gland chromosomes also hypertrophy and lack the nor- mal ecdysone-induced puffs. Chromosomes in both tissues respond to adminstration of ecdysone by producing the charac- teristic set of puffs (Holden and Ashburner, 1978, Chromosoma 68: 205-27). At 29 imaginal discs unable to evert in situ; however evert normally if cultured in the presence of ecdys- terone or in wild-type hosts. Implantation of a single wild- type ring gland rescues lethality (Holden, Walker, Maroy, Wat- son, White, and Gausz, 1986, Dev. Genet. 6: 153-62). # l(3)DTS-I165 origin: Induced by ethyl methanesulfonate in TM2. discoverer: Suzuki. references: Falke and Wright, 1972, DIS 48: 89-91. phenotype: Among progeny of TM2, l(3)DTS-I165/Sb by Oregon R crosses raised at 30 no lethal-bearing progeny survive when lethal inherited from father, but survival of lethal hetero- zyotes is 4% when lethal inherited from mother. #*l(3)e: lethal (3) with ebony location: 3- (not located). origin: Spontaneous in In(3R)C, e. discoverer: Schultz. phenotype: Dies as fully-developed, normal-appearing imago unable to eclose. RK3A. # l(3)ET: lethal (3) Elaine Tasaka A series of ethyl-methanesulfonate-induced temperature-sen- sitive mutations induced by Tasaka and Suzuki (1973, Genetics 74: 509-20). Genetically mapped, but individual positions not given; most clustered between st and Sb. Heat-sensitive and cold-sensitive mutants as well as alleles sensitive to both high and low temperatures reported. genetic locus location ref ( type of allele phenotype ____________________________________________________________________________ l(3)ET2 2 cold sensitive l(3)ET4 1 heat and adult males die on shift to 28 cold sensitive l(3)ET5 1, 2 heat and males sterile at 22 cold sensitive l(3)ET6 1 heat sensitive males sterile at 28 l(3)ET7 1 heat and males sterile at 22 cold sensitive l(3)ET8 1 heat sensitive males sterile at 28; motile sperm l(3)ET9 | 3-47.9 2 heat sensitive does not complement l(3)ET23 l(3)ET10 2 heat sensitive tergites deranged l(3)ET13 1 heat sensitive males sterile at 28; no motile sperm l(3)ET15 1 heat sensitive males sterile at 28; motile sperm l(3)ET16 3-71.5 2 heat sensitive wings wrinkled longitudinally l(3)ET18 2 heat sensitive half-sized flies at 29 l(3)ET23 2 heat sensitive does not complement l(3)ET9 l(3)ET26 2 cold sensitive ( 1 = Shellenbarger and Cross, 1979, Dev. Biol. 71: 308-22; 2 = Tasaka and Suzuki, 1973, Genetics 74: 509-20. | See Splts. # l(3)F: lethal (3) Ferrus A series of mutants selected by virtue of their abnormal phenotypes in homozygous clones; in all cases homozygous indi- viduals turned out to be lethal. origin: Induced with ethyl-methanesulfonate. references: Ferrus, 1979, Dev. Biol. 68: 16-28 (fig.). locus location lethal phase phenotype in clones ____________________________________________________________________ l(3)F12 3-18.2 L2 whorls and bulges of cells in wing l(3)F13 3-21 L2 large clones show late loss of cells l(3)F19 3-4.6 L1-L2 large clones show late loss of cells l(3)F23 3-22.5 L2 large clones show late loss of cells l(3)F24 3-76.7 L3 swollen cells and long hairs in wing l(3)F31 ( 3-62 L3 in wing and abdomen invaginate producing no hairs or bristles l(3)F34 3-10.6 L1 wing clones small and narrow l(3)F55 3-14.7 L1 wing clones small and narrow l(3)F60 3-35 L2-L3 wing and notum clones distorted ( Placed in 90C1-91A2 based on inclusion in Df(3R)sr. # l(3)gl: lethal (3) giant larvae origin: Induced with ethyl-methanesulfonate. references: Gateff, 1977, DIS 52: 4. 1978, Biol. Rev. 53: 123-42. 1978, Science 200: 1448-59. phenotype: Late larval lethal; larvae bloated, enlarged; tran- sparent owing to reduced fat body. Third larval instar may be prolonged for up to one week. Imaginal discs represent tran- splantable benign and lethal neoplasms; brain develops a malignant neuroblastoma. Penetrance incomplete. #*l(3)hd: lethal (3) head defect location: 3- (not located). discoverer: Bridges, 1924. references: Morgan, Bridges, and Sturtevant, 1925, Bibliog. Genet. 2: 230. phenotype: Dies in pupal stage with black, tumor-like growth in head. RK3. # l(3)Lh: see l(3)80F # l(3)LVML: lethal (3) L.V. Morgan Left # l(3)LVMR: lethal (3) L.V. Morgan Right Recessive lethal alleles associated with In(3L)P and In(3R)P respectively in the LVM balancer (Craymer, 1980, DIS 55: 197-204). # l(3)mbn: lethal (3) malignant blood neoplasm origin: Induced by ethyl-methanesulfonate. references: Gateff, 1977, DIS 52: 4. 1978, Biol. Rev. 53: 123-42. 1978, Science 200: 1448-59. phenotype: Lethal at pupariation; larvae appear bloated owing to having 150 times as many free hematocytes as normal; these can encapsulate and melanize larval tissue. # l(3)nc99Eb location: 3-54.2. references: Warmke, Krevz, and Falkenthal, 1989, Genetics 122: 139-51. phenotype: Homozygous lethal; heterozygous flightless; interacts semilethally with heterozygous deficiency for Mlc2, i.e., Df(3R)99D3-E3. # l(3)PL: l (3) Payne Left location: 3- (left arm). origin: Spontaneous in 3L carrying In(3L)P. # l(3)PR: l (3) Payne Right location: 3-90.2. origin: Spontaneous in In(3R)P. phenotype: Homozygous lethal; lethal in combination with M(3)96CF. RK3. # l(3)QIII: see M(3)80 # l(3)R A series of late larval lethal mutations that complement one another in all pairwise combinations; not mapped; screened for antigens with 16 different antisera on double diffusion plates (Roberts and Evans-Roberts, 1976, Mol. Gen. Genet. 148: 57- 64). locus comments ________________________________________________ l(3)R4 L1, may live to 5 days; polyphasic l(3)R15 P, monophasic l(3)R18 L3, may live to 13 days; polyphasic l(3)R26 L-P, polyphasic l(3)R33 L-P, polyphasic l(3)R45 L-P, polyphasic l(3)R52 L-P, polyphasic l(3)R70 L3, may live to 10 days; polyphasic l(3)R73 L1-2, polyphasic l(3)R76 see l(3)68Am l(3)R78 L3, may live to 10 days; polyphasic l(3)R88 l(3)R102 L-P, polyphasic l(3)R112 L-P, polyphasic l(3)R115 L3, may live to 14 days; monophasic l(3)R138 L3, may live to 30+ days; lack larval serum proteins, monophasic l(3)R142 L-P, polyphasic l(3)R159 L-P, polyphasic l(3)R200 L3, may live to 12 days; monophasic l(3)R260 L1, may live to 7 days; monophasic l(3)R340 L1, may live to 5 days; monophasic l(3)R350 L-P, polyphasic # l(3)R12 location: 3-{51}. origin: Induced by ethyl methanesulfonate. references: Caggese, Caizzi, Morea, Scalenghe, and Ritossa, 1979, Proc. Nat. Acad. Sci. USA 76: 2385-89. cytology: Placed in 87A6-D5 based on its failure to complement Df(3R)kar-D2 = Df(3R)87A6-7;87D4-5. Not checked for complemen- tation with known l(3)87 mutants. # l(3)Rh: see l(3)81F # l(3)S1: lethal (3) of Schalet location: 3-51 (to the left of kar). origin: X ray induced in a kar2 chromosome. discoverer: Schalet. other information: Placed to the left of l(3)S2 on the basis of its exclusion from Df(3R)ry76, which is deficient for l(3)S2 and loci to the right. # l(3)S1a origin: X ray induced in a kar2 chromosome. discoverer: Schalet. other information: Allelism with l(3)S1 tentative and based on similarity in interaction with Df(3R)ry76. # l(3)S2 location: 3-51.5 [between l(3)S1 and kar]. origin: X ray induced in a kar2 chromosome. discoverer: Schalet. references: Schalet, Kernaghan, and Chovnick, 1964, Genetics 50: 1261-68. other information: Placed between l(3)S1 and kar on the basis of its inclusion in Df(3R)ry76 but not Df(3R)ry29, Df(3R)ry33, or Df(3R)ry36. None of these deficiencies includes l(3)S1 and all include kar and genes to its right. # l(3)S3: see l(3)87Da # l(3)S4 location: 3-52.1 (to the right of pic). origin: X ray induced in a kar2 chromosome. discoverer: Schalet. references: Schalet, Kernaghan, and Chovnick, 1964, Genetics 50: 1261-68. phenotype: Homozygous lethal, but there are a few, relatively normal-appearing survivors that are mostly females. RK3. other information: Placed to the right of ry by recombination and to the right of pic on the basis of its survival in combi- nation with ry35, which behaves as though it were deficient for ry and pic. Placed to the left of l(3)S5 by recombina- tion. # l(3)S5: see l(3)87Db # l(3)S6: see l(3)87Eb # l(3)S7 location: 3-53 [to the right of l(3)26]. origin: X ray induced in a kar2 chromosome. discoverer: Schalet. references: Schalet, Kernaghan, and Chovnick, 1964, Genetics 50: 1261-68. alleles: Five alleles recovered; l(3)S72 - l(3)S75 originally designated l(3)S7a - l(3)S7d. l(3)S71 but not l(3)S72 or l(3)S73 complemented by an undescribed red deficiency. other information: Placed to the right of l(3)26 on the basis of its exclusion from Df(3R)ry66, which includes l(3)26 and loci to its left. # l(3)SG: lethal (3) of Shearn and Garen Recessive lethal third-chromosome mutations in ninety-four loci isolated by Shearn and Garen (or occasionally by Shearn: SG4, SG5, SG6, SG16, SG28, SG30, SG35, SG44, SG64, SG68, SG70) mostly selected to be late larval or prepupal lethals. For simplicity they are designated numerically in their genetic map order; those that are unmapped continue the list at the end according to isolation number. As these loci become cyto- logically mapped or otherwise named, their SG designations will sink to synonomy. locus synonym location origin ref ( phenotype _______________________________________________________________________________________________ l(3)SG1 G60L 3-0.0 EMS 9 L3-EP; discs missing l(3)SG2 13m237 3-2.4 EMS 2, 6 L3; discs small; mitotic index normal l(3)SG3 M47 3-4.3 EMS 2, 9 EP; eye-antenna and leg discs differentiate abnormally; wing and haltere discs normal; mitosis normal l(3)SG4 XII-10L 3-10.7 ICR170 9 discs normal; mitosis normal l(3)SG5 MS332 3-12.1 EMS L2; discs normal l(3)SG6 2813 3-12.4 NNG 5, 9 P; discs normal l(3)SG7 J16 3-15.6 EMS L3-EP; eye-antennal disc and wing disc small; haltere and leg discs missing; mitosis normal l(3)SG8 | 1602 3-19.6 NNG 8, 9 L2; discs small l(3)SG9 17m28 3-22.2 EMS 6 discs small l(3)SG10 m27 3-23.3 EMS 2, 9 L3; discs normal; mitosis normal l(3)SG11 15m33 3-24.0 EMS 2, 6 discs small; mitosis normal l(3)SG12 J51 3-25.5 EMS 2, 9 EP-P; discs normal; mitosis normal l(3)SG13 | E20 3-25.9 EMS 2, 9 L3-EP; discs missing; abnormal mitoses l(3)SG14 13m281 3-26.6 EMS 2, 6 discs small; highly polyploid, endoreduplicated cells; very low mitotic index l(3)SG15 VII-3 3-29.2 ICR170 9 EP-P; haltere disc normal; other discs differentiate abnormally l(3)SG16 1509 3-29.3 NNG 5, 9 L3-EP; discs normal l(3)SG17 E(z), pco, l(3)67Fa 3-30.9 NNG 2, 7, 8, 9 L3-EP; discs small; low 1902 mitotic index l(3)SG18 8m100 3-31.9 EMS 6 L3; discs small l(3)SG19 605 3-34.0 NNG7 L3-EP; eye-antenna disc develops abnormally; other discs normal; mitosis normal l(3)SG20 l(3)68Ad 3-35.7 NNG 2, 6 L3-EP; discs small; mitosis 517 normal l(3)SG21 7m62 3-36.8 EMS 2, 6 discs small; 77% highly polypolid cells; no mitotic block l(3)SG22 15m15 3-37.8 EMS 2, 6 discs small; mitosis normal l(3)SG23 G49 3-39.4 EMS 2, 9 L3-EP; discs differentiate abnormally; mitosis normal l(3)SG24 V-1 3-41 ICR170 9 L3; eye-antenna, wing, and third-leg discs differentiate abnormally; other discs normal l(3)SG25 | G30L 3-41.4 EMS 9, 10 L3; discs missing l(3)SG26 G26 3-42.9 EMS 6 L3; discs small l(3)SG27 IX-19 3-44.1 ICR170 9 L2-3; discs small l(3)SG28 8m12 3-46.4 EMS 2, 6 discs missing; swollen fuzzy chromosomes; low mitotic index l(3)SG29 | O52 3-47.0 EMS 8, 9 EP; discs small l(3)SG29a l(3)III-10 3-46.6 ICR170 5 l(3)SG30 Q13 3-47.2 EMS 9 EP; eye-antenna disc differentiates abnormally; other discs normal l(3)SG31 2612 3-48.7 NNR 2, 9 L3; discs small; unevenly condensed, swollen chromosomes; 10% polyploid cells; low mitotic index l(3)SG32 C21L 3-48.7 EMS 2, 9 discs normal; mitoses normal l(3)SG33 l(3)85Ea 3-49.0 EMS 2, 3, 9 PP; eye-antennal disc small; C43 wing and haltere discs large; leg discs abnormal; genital disc normal; heat sensitive; mitosis normal l(3)SG34 IX-14 3-49.0 ICR170 2, 9 L2-3; discs small; fuzzy, swollen chromosomes; chromosome breaks l(3)SG35 l(1)85Eb 3-49.2 EMS 5, 9 EP; discs normal J5 l(3)SG36 11m254 3-49.3 EMS 2, 6 discs missing; weak effect on chromosome condensation; low mitotic index l(3)SG37 P4 3-49.3 EMS 9 L3; discs small l(3)SG38 m45 3-49.5 EMS 2, 9 L3-EP; discs differentiate abnormally; mitosis normal l(3)SG39 l(1)85Ec 3-49.8 EMS 9 discs normal WG89 l(3)SG40 l(3)88Aa 3-50.3 NNG 2, 9 L3; discs missing; fuzzy, 2004 swollen chromosomes; 27% polyploid cells (Gatti) l(3)SG41 507 3-50.8 NNG 9 L3, discs small; swollen unevenly condensed chromosomes l(3)SG42 N61 3-50.9 EMS 9 L3; discs small l(3)SG43 GA55 3-51.0 gamma discs missing l(3)SG44 l(3)88Ab 3-51.1 EMS 2, 9, 10 EP; discs missing; extremely low K43 mitotic index; irregular chromosome condensation; chromosome breaks l(3)SG45 7m68 3-51.8 EMS 2, 6 L3; discs small; mitosis normal; low mitotic index l(3)SG46 G21 3-52.1 EMS 2, 9 L2-3; leg discs differentiate abnormally; other discs normal l(3)SG47 7m141 3-53.2 EMS 6 discs small l(3)SG48 7m70 3-53.4 EMS 6 discs small l(3)SG49 427 3-53.6 EMS 9 L3-EP; discs small l(3)SG50 7m75 3-53.8 EMS 2, 6 discs small; weakly affects chromosome condensation; some chromosome brokage l(3)SG51 13m112 3-55.0 EMS 6 L3; discs small l(3)SG52 15m25 3-58 EMS 2, 6 discs missing; elongated, fuzzy, unevenly condensed chromosomes; chromosome brokage l(3)SG53 1803L 3-59.3 EMS 2, 9 E; discs normal; mitosis normal l(3)SG54 1803X 3-59.3 EMS E; discs normal; heat sensitive l(3)SG55 L36 3-62.4 EMS 2, 9 EP-P; discs normal; mitosis normal l(3)SG56 | C21R 3-62.5 EMS 1, 2, 4, 9 L3; discs small; mitosis normal l(3)SG57 7m147 3-68.7 EMS 2, 6 discs missing; mitosis normal l(3)SG58 IIB1 3-70.4 ICR170 2, 9 L3; discs missing; low mitotic index; condensation irregular l(3)SG59 13m133 3-71 EMS 6 discs missing l(3)SG60 2306 3-74.0 NNG 2, 9 L3-EP; discs small; mitosis normal l(3)SG61 XI-2 3-76.6 ICR170 9 L3; discs missing l(3)SG62 XII-10R 3-76.6 ICR170 2, 9 L3; discs small; weak effect on chromosome condensation- chromosome breakage; 4% polyploid cells l(3)SG63 7M124 3-78.2 EMS 6 discs missing l(3)SG64 G30R 3-79.8 EMS 2, 5, 9 discs normal; mitosis normal l(3)SG65 703 3-78.6 NNG 5 transforms arista to tarsus, haltere to wing, genital disc to leg l(3)SG66 G60A 3-81.4 EMS 2, 6, 9 L3-EP; discs small; chromosomes elongated, unevenly condensed; some chromosome breakage l(3)SG67 | IX-11 3-81.7 ICR170 2, 8, 9 EP; discs small; extremely low mitotic index; thin, elongated chromosomes l(3)SG68 F26 3-82.7 EMS 9 L3; discs missing l(3)SG69 L6B20 3-84.5 EMS 9 discs normal, mitosis normal l(3)SG70 | 12m137 3-106 EMS 2, 6 discs missing; weak effect on chromosome condensation l(3)SG71 903 3-110.9 NNG 9 L3; discs differentiate abnormally l(3)SG72 4m109 EMS E-L1; discs normal l(3)SG73 5m216 EMS 6 discs normal l(3)SG74 5m276 EMS E-L1; discs normal l(3)SG75 5m323 EMS discs normal l(3)SG76 7m177 EMS discs normal; heat sensitive l(3)SG77 9m228 EMS 6 L3; discs normal l(3)SG78 12m86 EMS 6 discs normal l(3)SG79 609 NNG P-A; discs normal; heat sensitive l(3)SG80 1117 NNG L3-EP; discs normal l(3)SG81 1403 NNG P; discs normal l(3)SG82 1708 NNG L3-EP; discs normal; heat sensitive l(3)SG83 1711 NNG 9 L3-EP; eye-antenna and genital discs develop abnormally; other discs normal; mitosis normal l(3)SG84 2614 NNG 2, 9 EP; eye-antenna disc develops abnormally; other discs normal; mitosis normal l(3)SG85 C12 EMS E; discs normal; heat sensitive; TSP = E-EP l(3)SG86 C35 EMS L3; discs normal; heat sensitive; TSP = L3 l(3)SG87 E26R EMS 9 discs normal; mitosis normal l(3)SG88 H2J3 EMS E-L1; discs normal l(3)SG89 H3J79 EMS discs normal; heat sensitive l(3)SG90 K60 EMS 2, 9 EP-P; leg discs differentiate abnormally; other discs normal; mitosis normal l(3)SG91 K64 EMS L1-2; discs normal; heat sensitive; TSP = E-L2 l(3)SG92 M38 EMS discs normal l(3)SG93 V-13 ICR170 2, 9 L3-EP; discs differentiate abnormally; mitosis normal l(3)SG94 R12 EMS EP-P; discs normal ( 1 = Cheney, Miller, Lang, and Shearn, 1984, Proc. Nat. Acad. Sci. 81: 6422-26; 2 = Gatti and Baker, 1989, Genes Dev. 3: 438-53; 3 = Martin, Martin, and Shearn, 1977, Dev. Biol. 55: 213-32; 4 = Pentz and Shearn, 1979, Dev. Biol. 70: 149-70; 5 = Shearn, 1974, Genetics 77: 115-25; 6 = Shearn and Garen, 1974, Proc. Nat. Acad. Sci. USA 71: 1393-97; 7 = Shearn, Hersperger, and Hersperger, 1978, Genetics 89: 341-53; 8 = Shearn, Hersperger, Hersperger, Pentz, and Denker, 1978, Genetics 89: 355-70; 9 = Shearn, Rice, Garen, and Gehring, 1971, Proc. Nat. Acad. Sci. USA 68: 2594-98; 10 = Szabad and Bryant, l982, Dev. Biol. 93: 240-56. | Additional information below. allele synonym ______________________ l(3)SG51 l(3)MS332 l(3)SG52 l(3)NW1127 l(3)SG61 l(3)2813 l(3)SG62 l(3)1307 l(3)SG71 l(3)J16 l(3)SG72 l(3)RE620 l(3)SG73 l(3)RG502 l(3)SG74 l(3)RI506 l(3)SG75 l(3)RJ022 l(3)SG76 l(3)RT119 l(3)SG77 l(3)SJ015 l(3)SG78 l(3)SN423 l(3)SG79 l(3)UM110 l(3)SG710 l(3)UO321 l(3)SG711 l(3)VC266 l(3)SG712 l(3)VF287 l(3)SG713 l(3)UK14 l(3)SG714 l(3)VL476 l(3)SG715 l(3)VQ350 l(3)SG716 l(3)VQ441 l(3)SG717 l(3)VR414 l(3)SG718 l(3)VS300 l(3)SG720 l(3)VX266 l(3)SG721 l(3)VZ292 # l(3)SG8 phenotype: Homozygous larvae never form puparia; imaginal discs never exceed size seen in late second instar, neither do they grow when transplanted into normal adult female abdomens nor differentiate when transplanted back into wild-type larval hosts for metamorphosis (Shearn, Hersperger, Hersperger, Pentz, and Denker, 1978, Genetics 89: 355-70). alleles: All alleles noncomplementing. allele synonym _______________________ l(3)SG81 l(3)GTK512 l(3)SG82 l(3)MP120 l(3)SG83 l(3)MS023 l(3)SG84 l(3)MZ121 l(3)SG85 l(3)NC502 l(3)SG86 l(3)NF022 l(3)SG87 l(3)NS040 l(3)SG88 l(3)OG019 l(3)SG89 l(3)OI233 l(3)SG810 l(3)ON1235 l(3)SG811 l(3)OR1505 l(3)SG812 l(3)OS1236 l(3)SG813 l(3)OU1115 l(3)SG814 l(3)PA037 l(3)SG815 l(3)PB1131 l(3)SG816 l(3)PC914 l(3)SG817 l(3)PD1001 l(3)SG818 l(3)PD1138 l(3)SG819 l(3)PF834 l(3)SG820 l(3)PJ323 l(3)SG821 l(3)PO432 l(3)SG822 l(3)PU927 l(3)SG823 l(3)JPW1029 l(3)SG824 l(3)PZ913 l(3)SG825 l(3)QG1026 l(3)SG826 l(3)QI125 l(3)SG827 l(3)QL1136 l(3)SG828 l(3)QM509 l(3)SG829 l(3)QM629 l(3)SG830 l(3)QO022 l(3)SG831 l(3)RG509 l(3)SG832 l(3)RM329 l(3)SG833 l(3)RN330 l(3)SG834 l(3)VI307 l(3)SG835 l(3)VL469 l(3)SG836 l(3)VQ314 l(3)SG837 l(3)VX242 # l(3)SG13 phenotype: Homozygous larvae contain rudimentary imaginal discs, but disc primordia do not grow during larval develop- ment; testes and ovaries smaller than normal, and cell number in central nervous system reduced. Mutant gonads do not sur- vive metamorphosis when implanted into wild-type larvae. Homozygous cuticular clones appear to develop normally. Mutant larvae support growth of implanted wild-type discs. Normal gene product postulated to be required for cell proli- feration; survival of somatic epidermal clones attributed to perdurance. Larval ganglia exhibit extremely low mitotic index; chromosomes irregularly condensed; extensive chromosome fragmentation observed frequently (Gatti and Baker, 1989, Genes Dev. 3: 438-53); salivary chromosomes appear normal. allele synonym ____________________ l(3)SG161 l(3)1509 l(3)SG162 l(3)1905 l(3)SG231 l(3)G49 l(3)SG232 l(3)m75 # l(3)SG25 phenotype: Homozygous larvae contain rudimentary imaginal discs, but disc primordia do not grow during larval develop- ment; testes and ovaries smaller than normal, and cell number in central nervous system reduced; mitotic abnormalities observed but salivary chromosomes appear normal. Mutant gonads do not survive metamorphosis when implanted into wild-type larvae. Homozygous cuticular clones appear to develop nor- mally. Mutant larvae support growth of implanted wild-type discs. Normal gene product postulated to be required for cell proliferation; survival of somatic epidermal clones attributed to perdurance. allele synonym ______________________ l(3)SG261 l(3)G26 l(3)SG262 l(3)13m115 l(3)SG263 l(3)E26 # l(3)SG29 phenotype: Homozygous larvae do not form puparia; imaginal discs never attain size of those in young third-instar larvae. Mutant discs transplanted into wild-type female abdomens decrease in size and disappear during the first three days; however, in transplanted mixtures of wild-type and mutant embryonic cells allowed to pass through metamorphosis, mutant cells appear in cuticular derivatives from all discs. Wild- type discs transplanted into mutant larvae are capable of reduced growth and of differentiation upon retransplantation into wild-type larvae. Alleles with more extreme effects (i.e., larval death in early second instar) and less severe effects (pharate adults that do not eclose) noted (Shearn, Hersperger, Hersperger, Pentz, and Denker, 1978, Genetics 89: 355-70). alleles: Interallelic complementation not observed; heteroal- lelic combinations exhibit phenotypes intermediate between those of the two homozygotes. allele synonym _______________________ l(3)SG291 l(3)O52 l(3)SG292 l(3)MJ727 l(3)SG293 l(3)MV1424 l(3)SG294 l(3)MZ416 l(3)SG295 l(3)NI428 l(3)SG296 l(3)ON1212 l(3)SG297 l(3)OS218 l(3)SG298 l(3)OU902 l(3)SG299 l(3)OY933 l(3)SG2910 l(3)OZ831 l(3)SG2911 l(3)PE414 l(3)SG2912 l(3)PF123 l(3)SG2913 l(3)PL1117 l(3)SG2914 l(3)PO610 l(3)SG2915 l(3)PX837 l(3)SG2916 l(3)PX929 l(3)SG2917 l(3)PZ227 l(3)SG2918 l(3)QB212 l(3)SG2919 l(3)QE1103 l(3)SG2920 l(3)QM709 l(3)SG2921 l(3)RO022 l(3)SG2922 l(3)SE508 l(3)SG2923 l(3)VL51 l(3)SG2924 l(3)VL250 l(3)SG2925 l(3)VP305 l(3)SG2926 l(3)VP339 l(3)SG2927 l(3)VX340 l(3)SG2928 l(3)VY53 l(3)SG2929 l(3)VZ412 l(3)SG2930 l(3)VZ160 l(3)SG2931 l(3)WD545 l(3)SG29a1 l(3)III-10 l(3)SG29a2 l(3)XVI-18 l(3)SG551 l(3)L23 l(3)SG552 l(3)L36 # l(3)SG56 references: Shearn, Hersperger, Hersperger, Pentz, and Denker, 1978, Genetics 89: 355-70. Pentz and Shearn, 1979, Dev. Biol. 70: 149-70 (fig.). Cheney, Miller, Lang, and Shearn, l984, Proc. Nat. Acad. Sci. USA 81: 6422-26. phenotype: 78% of mutant larvae reach third instar; development delayed, and larvae never pupariate; rather they remain alive on surface of food for up to 22 days. Larvae form melanotic masses. Imaginal disc growth retarded and development abnor- mal, with substantial cell death; growth rate of mutant discs, but not their ability to differentiate, partially restored when transplanted into normal larval host; mutant larvae defective in support of growth of implanted wild-type discs, but do not prevent their subsequent differentiation upon retransplantation into normal larvae. Homozygous mutant clones in a wild-type background were induced at control fre- quencies; however, sizes of mutant clones produced earlier, but not those produced later, were smaller than control clones; differentiation of cuticular elements normal in small clones, but in large thoracic clones produced in a M back- ground cuticular development abnormal (Pentz and Shearn). Ganglion mitosis normal according to Gatti and Baker (1989, Genes Dev. 3: 438-53), disturbed according to Pentz. l(3)SG5626 homozygotes lethal when raised at 27 but survive as fertile adults when reared at 20; shifting such adult females to 27 demonstrates that l(3)SG56 is a maternal-effect lethal and a female sterile; egg production decreases with time, and those eggs that are produced exhibit abnormal cellularization and fail to hatch; temperature effect reversable by shift down. Two-dimensional gel electrophoresis analysis of pro- teins from mutant tissue at restrictive vs. permissive tem- peratures shows reduction in levels of three proteins and a concommitant increase of three related proteins; two other proteins are absent from mutant tissue at restrictive tempera- tures; mutant postulated to be defective in post-translational modification of a small subset of proteins crucial to normal cell division, cell motility, and formation of adult hairs and bristles (Cheney, et al.). alleles: No complementation between alleles observed. l(3)SG566 hypomorphic; completes metamorphosis but dies as pharate adult without striking morphological defects. l(3)SG5626 heat sen- sitive. allele synonym ________________________ l(3)SG561 l(3)C21R l(3)SG562 l(3)CR12 l(3)SG563 l(3)CR125 l(3)SG564 l(3)MW416 l(3)SG565 l(3)NB215 l(3)SG566 l(3)NC806R2 l(3)SG567 l(3)NZ806 l(3)SG568 l(3)OI1015 l(3)SG569 l(3)OL1112 l(3)SG5610 l(3)OL1116 l(3)SG5611 l(3)OM901 l(3)SG5612 l(3)OX502 l(3)SG5613 l(3)PA734 l(3)SG5614 l(3)PB427 l(3)SG5615 l(3)PD432 l(3)SG5616 l(3)PY910 l(3)SG5617 l(3)PZ007 l(3)SG5618 l(3)QB1001 l(3)SG5619 l(3)QE1321 l(3)SG5620 l(3)QE1332 l(3)SG5621 l(3)QG1329 l(3)SG5622 l(3)QN407 l(3)SG5623 l(3)QR233 l(3)SG5624 l(3)QU1040 l(3)SG5625 l(3)RN323 l(3)SG5626 l(3)RW630 l(3)SG5627 l(3)UQ295 l(3)SG5628 l(3)UQ335 l(3)SG5629 l(3)VL475 l(3)SG591 l(3)13m133 l(3)SG592 l(3)7M63B l(3)SG641 l(3)e21R l(3)SG642 l(3)g30R l(3)SG643 l(3)g60R l(3)SG644 l(3)g131 l(3)SG645 l(3)n3 l(3)SG646 l(3)o51r l(3)SG647 l(3)g6 l(3)SG651 l(3)703 l(3)SG652 l(3)1803R # l(3)SG67 phenotype: Homozygotes pupariate, but do not metamorphose; ima- ginal discs never exceed in size those of late second-instar larvae. Mutant eye-antennal and wing discs transplanted into adult wild-type female abdomens are never recovered after seven days in culture; they decrease in size and disappear during first three days. Mutant larvae permit reduced growth of implanted wild-type discs and do not interfere with their subsequent development in normal hosts (Shearn, Hersperger, Hersperger, Pentz, and Denker, 1978, Genetics 89: 355-70). Larval ganglion cells exhibit extremely low mitotic index and weak effects on chromosome condensation; chromosomes thin and elongated (Gatti and Baker, 1989, Genes Dev. 3: 438-53). alleles: All alleles noncomplementing. allele synonym _______________________ l(3)SG671 l(3)IX-11 l(3)SG672 l(3)GSS408 l(3)SG673 l(3)NH812 l(3)SG674 l(3)NL522 l(3)SG675 l(3)NL920 l(3)SG676 l(3)NR821 l(3)SG677 l(3)NV1101 l(3)SG678 l(3)OF840 l(3)SG679 l(3)OH633 l(3)SG6710 l(3)ON1227 l(3)SG6711 l(3)OS334 l(3)SG6712 l(3)OS335 l(3)SG6713 l(3)PC914 l(3)SG6714 l(3)PK829 l(3)SG6715 l(3)QA1001 l(3)SG6716 l(3)QB201 l(3)SG6717 l(3)QB427 l(3)SG6718 l(3)QL827 l(3)SG6719 l(3)RS109 l(3)SG6720 l(3)SD715 l(3)SG6721 l(3)VC180 l(3)SG6722 l(3)VJ121 l(3)SG6723 l(3)VS384 l(3)SG6724 l(3)XVI-3 # l(3)SG70 phenotype: Homozygous larvae contain rudimentary imaginal discs, but disc primordia do not grow during larval develop- ment; testes and ovaries smaller than normal, and cell number in central nervous system reduced. Mutant gonads do not sur- vive metamorphosis when implanted into wild-type larvae. Homozygous cuticular clones appear to develop normally, but with reduced frequency and size compared to control clones. Mutant larvae support growth of implanted wild-type discs. Normal gene product postulated to be required for cell proli- feration; survival of somatic epidermal clones attributed to perdurance. Larval ganglion mitoses exhibit weak effect on chromosome condensation as well as chromosome breakage (Gatti and Baker, 1989, Genes Dev. 3: 438-53); salivary chromosomes appear normal. # l(3)Sp: lethal (3) of Spiess A series of recessive lethal mutations extracted from a long term (170 generations) laboratory population. references: Spiess, Helling, and Capenos, 1963, Genetics 48: 1377-88. genetic locus location __________________ *l(3)Sp1 3-33.8 *l(3)Sp2 3-79.3 *l(3)Sp3 3-41.0 *l(3)Sp6 3-40.4 *l(3)Sp9 3-101.1 *l(3)Sp10 3-41.7 *l(3)Sp17 3-38.4 *l(3)Sp19 3-100.9 # l(3)tl: lethal (3) tumorous larvae location: 3- to the left of R (3-1.4). origin: Spontaneous. references: Peterson and Gardner, 1965, Genetics 52: 465-66. Kobel and Breugel, 1967, Genetica 38: 305-27. Zhimulev and Lychev, 1972, Genetika (Moscow) 8(6): 51-55. Zhimulev, Belyaeva, and Lychev, 1974, Genetika (Moscow) 10(10): 73-79 (fig.). Zhimulev, Belyaeva, and Lychev, 1976, Chromosoma 55: 121-26. phenotype: Homozygous larvae fail to pupate and live beyond normal time of pupation. Hemolymph contains an overabundance of blood cells as well as melanotic pseudotumors. Fat bodies and parts of gut disintegrate. Salivary nuclei contain nucleolus-like bodies six to seven times normal size; polytene chromosomes short, thick, and diffuse, especially the male X; bands appear to fuse. Mutant eye-antennal discs allowed to metamorphose in normal larvae produce some normal adult struc- tures. # l(3)tr: lethal (3) translucida location: 3-20 (18.1 to 22.0). origin: Spontaneous. discoverer: Hadorn, 40l16. references: 1947, Expt. Biol. Symp., Vol. 2: 177-95, Cambridge Univ. Press. 1947, DIS 21: 68. 1956, Cold Spring Harbor Symp. Quant. Biol. 21: 363-73 (fig.). phenotype: Larvae become bloated and transparent from accumula- tion of abnormal amount of hemolymph. Concentration of amino acids in hemolymph higher than normal; concentration of pro- teins reduced. Pupation delayed one day (25); dwarfed pupae formed in inflated puparia; death follows pupation or comple- tion of imaginal differentiation of head and thorax; abdomen never metamorphoses. After transplantation into normal hosts, imaginal disks develop normally; ovaries also develop normally and are fully capable of producing viable eggs [Sobels, 1950, Experientia 6: 139-40 (fig.)]. In pure oxygen, frequency and extent of imaginal differentiation strongly increased [Sobels and Nijenhuis, 1953, Z. Indukt. Abstamm. Vererbungsl. 85: 579-92 (fig.)]. RK3. cytology: Salivary chromosomes normal (Rosin). # l(3)W location: 3- (right arm). origin: Spontaneous in 3R carrying In(3R)P. # l(3)XaR location: 3-91.8. other information: Used to balance T(2;3)apXa. # l(4)102 The following represents the results of extensive searches for mutations on chromosome 4, largely carried out by Hochman. Mutants can be examined for their ability to complement Df(4)M4 and Df(4)G; those that complement both deficiencies are assumed to be located between them, although it is possi- ble that some are located proximal to Df(4)M4. references: Hochman, Gloor, and Green, 1964, Genetica 35: 109-26. Hochman, 1971, Genetics 67: 235-52. Hochman, 1973, Cold Spring Harbor Symp. Quant. Biol. 38: 581-89. Hochman, 1976, Genetics and Biology of Drosophila (Ashburner and Novitski, eds.). Academic Press, London, New York, and San Francisco, Vol. 1b, pp. 903-24. cytological lethal locus location included in excluded from synonym phase _____________________________________________________________________ l(4)102ABa 102A1-2 Df(4)M101-63a M(4)101 L l(4)102ABb 102B2-17 Df(4)M101-1 Df(4)M101-63a l(4)13 l(4)102ABc 102B2-17 Df(4)M101-1 Df(4)M101-63a Ce, l(4)17 E/L l(4)102ABd 102B2-17 Df(4)M101-1 Df(4)M101-63a l(4)1 L l(4)102ABe 102B2-17 Df(4)M101-1 Df(4)M101-63a l(4)18 A l(4)102ABf 102B2-17 Df(4)M101-1 Df(4)M101-63a l(4)20 P l(4)102ABg 102B2-17 Df(4)M101-1 Df(4)M101-63a l(4)24 L-P l(4)102ABh 102B2-17 Df(4)M101-1 Df(4)M101-63a l(4)25 L l(4)102ABi 102B2-17 Df(4)M101-1 Df(4)M101-63a l(4)26 L l(4)102CDa ( 102B6-E10 Df(4)M101-1 l(4)2 E Df(4)G l(4)102CDb 102B6-E10 Df(4)M l(4)23 E Df(4)G l(4)102CDc 102B6-E10 Df(4)M l(4)4 L Df(4)G l(4)102CDd 102B6-E10 Df(4)M l(4)5 E-L Df(4)G l(4)102CDe 102B6-E10 Df(4)M l(4)6 P Df(4)G l(4)102CDf 102B6-E10 Df(4)M l(4)7 E Df(4)G l(4)102CDg 102B6-E10 Df(4)M l(4)8 L-P Df(4)G l(4)102CDh 102B6-E10 Df(4)M l(4)10 E Df(4)G l(4)102CDi 102B6-E10 Df(4)M l(4)14 L Df(4)G l(4)102CDj 102B6-E10 Df(4)M l(4)15 P Df(4)G l(4)102CDk 102B6-E10 Df(4)M l(4)21 P Df(4)G l(4)102CDl 102B6-E10 Df(4)M l(4)22 P Df(4)G l(4)102CDm 102B6-E10 Df(4)M l(4)27 L Df(4)G l(4)102CDn 102B6-E10 Df(4)M l(4)28 L Df(4)G l(4)102CDo 102B6-E10 Df(4)M l(4)30 L Df(4)G l(4)102CDp 102B6-E10 Df(4)M l(4)31 P Df(4)G l(4)102CDq 102B6-E10 Df(4)M l(4)32 P Df(4)G l(4)102CDr | 102B6-E10 Df(4)M ey P Df(4)G l(4)33 l(4)102CDs 102B6-E10 Df(4)M l(4)34 A Df(4)G l(4)102CDt 102B6-E10 Df(4)M l(4)35 L Df(4)G l(4)102CDu 102B6-E10 Df(4)M l(4)36 P Df(4)G l(4)102CDv 102B6-E10 Df(4)M l(4)37 L Df(4)G l(4)102EFa 102E2-F10 Df(4)G l(4)9 P l(4)102EFb 102E2-F10 Df(4)G l(4)16 E-L l(4)102EFc ( 102E2-F10 Df(4)G l(4)29 P l(4)102EFd 102E2-F10 Df(4)G l(4)39 E-L l(4)102EFe | 102E2-F10 Df(4)G sv L l(4)40 l(4)102EFf 102F2-end Df(4)G l(4)19 P ( More detailed description below. | Genetic location as measured in diplo-4 triploids for l(4)102CDr: 4-2.0, l(4)102EFe: 4-3.0 (Sturtevant, 1951, Proc. Nat. Acad. Sci. USA 37: 405-07). alleles: origin of alleles ____________________ locus spont X ray EMS ICR-170 Melphalan _______________________________________________________ M(4) 1 l(4)102ABb 1 1 l(4)102ABc 2 l(4)102ABd 2 6 3 l(4)102ABe 1 l(4)102ABf 1 3 l(4)102ABg 10 l(4)102ABh 1 3 1 l(4)102ABi 1 1 l(4)102CDa 3 6 23 3 l(4)102CDb 1 6 1 l(4)102CDc 2 3 9 1 l(4)102CDd 1 1 9 l(4)102CDe 1 3 3 l(4)102CDf 1 3 l(4)102CDg 3 l(4)102CDh 1 1 1 l(4)102CDi 1 2 4 l(4)102CDj 3 l(4)102CDk 1 4 l(4)102CDl 1 l(4)102CDm 1 l(4)102CDn 3 l(4)102CDo 1 l(4)102CDp 1 l(4)102CDq 1 l(4)102CDs 1 l(4)102CDt 1 l(4)102CDu 4 l(4)102CDv 4 l(4)102EFa 2 2 l(4)102EFb 4 4 1 l(4)102EFc 4 l(4)102EFd 1 l(4)102EFf 2 4 2 # l(4)102CDa alleles: A highly mutable locus. The 35 alleles designated a through hh by Hochman; alleles b, k, and ii die in the larval stage and are mutually partially complementing; a fourth com- plementation group comprises alleles f, h, and t, which are larval lethals. The remaining 29 alleles are embryonic lethals and are noncomplementing. Allele c fails to comple- ment l(4)102CDb alleles as well. # l(4)102EFc (R. Denell) references: Hochman, Gloor, and Green, 1964, Genetica 35: 109-26. Gehring, 1970 DIS 45: 103. Hochman, 1971, Genetics 67: 235-52. Duncan, 1982, Genetics 102: 49-70. Sato, Russell, and Denell, 1983, Genetics 105: 357-70. phenotype: Homozygotes from heterozygous mothers die as pupae (Hochman). Those that reach the pharate-adult stage show par- tial homeotic transformations of first and second antennal segments into proximal leg structures, meso- and metathoracic legs into prothoracic legs, as well as posteriorly directed transformations of features of the abdominal hypoderm and of parovaria into spermathecae in females. All three pairs of legs distorted, with tarsal segments swollen and sometimes fused with missing claws; some abnormalities of derivatives of the antennal disc and of the dorsal prothorax also present (Gehring; Duncan). Heterozygous adults normal, except that males also heterozygous for a deficiency or mutation of E(Pc) occasionally develop sex-comb teeth on meso- and metathoracic legs (Sato et al.). Heterozygous and homozygous larvae from heterozygous mothers normal; homozygotes from transplanted homozygous ovaries die as late embryos with a complex homeotic syndrome. Head involution incomplete, and portions of head develop abdominal-like denticles. All thoracic segments par- tially transformed to resemble the first abdominal segment, and more posterior segments may develop cuticular features characteristic of the eighth abdominal segment. Heterozygtoes from homozygous ovaries sometimes die as late embryos display- ing relatively mild homeotic effects of the head and mesothorax or slightly incomplete head involution or both, but often hatch and die during larval or pupal stages. Rarely, adults eclose, often with appendages that are crippled or are missing owing to failure of imaginal-disc evagination (Denell). Most embryos produced by oocytes hemizygous for l(4)102EFc3 and l(4)102EFc4, achieved by pole-cell transplan- tation, fail to form cuticle, even with a wild-type paternal complement; a few of the latter genotype produce enough cuti- cle to reveal extensive defects in segmentation; setal belts usually missing or transformed; head involution fails; ante- rior hole present in most embryos (Breen and Duncan, 1986, Dev. Biol. 118: 442-45). alleles: allele origin discoverer synonym ref ( comments _________________________________________________________________________ l(4)102EFc1 spont Hochman, 62k l(4)BU-2 1, 2, 3, 4 l(4)29 l(4)102EFc2 spont Kidwell, 62l l(4)OC-1 4 l(4)29a l(4)102EFc3 spont Hochman, 63 l(4)29b 1, 2, 4 l(4)102EFc4 spont Duncan l(4)29c 1 hypomorphic allele ( 1 = Duncan, 1982, Genetics 102: 49-70; 2 = Gehring, 1970, DIS 45: 103; 3 = Hochman, 1971, Genetics 67: 235-52; 4 = Hochman, Gloor, and Green, 1964, Genetica 35: 109-26. DEFICIENCY MAP OF REGION 102 CHROMOSOME 4 side breakpoint variant ______________________________________ left 101E-F Df(4)M101-1 left 101E-F Df(4)M101-62e left 101E-F Df(4)M101-62f left 101F2-102A1 Df(4)M101-63a 102A1-2 M(4)101 102A1-2 ci right 102A2-5 Df(4)M101-63a right 102B2-5 Df(4)M101-62f left ciD ? l(4)102ABb Ce right ciD ? gvl ar l(4)102ABd l(4)102ABe l(4)102ABf l(4)102ABg l(4)102ABh l(4)102ABi right 102B6-17 Df(4)M101-1 left Df(4)btD ? left Df(4)2c ? l(4)102CDa l(4)102CDb right Df(4)btD right Df(4)2c l(4)102CDc l(4)102CDd l(4)102CDe l(4)102CDf l(4)102CDg l(4)102CDh l(4)102CDi l(4)102CDj l(4)102CDk l(4)102CDl l(4)102CDm l(4)102CDn l(4)102CDo l(4)102CDp l(4)102CDq ey l(4)102CDs l(4)102CDt l(4)102CDu l(4)102CDv right 102D13-E1 Df(4)M101-62e left 102E2-10 Df(4)11 left 102E2-10 Df(4)G left Df(4)3 ? left Df(4)38 ? left Df(4)Cat ? l(4)102EFa l(4)102EFb l(4)102EFc right Df(4)38 ? l(4)102EFd left Df(4)40 ? left l(4)14-310 sv right Df(4)Cat ? right Df(4)3 ? right l(4)14-310 spa right Df(4)40 ? right 102F2-10 Df(4)11 l(4)102EFf